2015年6月加入苏州大学后的研究论文(*:通讯作者):
Chen JLong F. mTORC1 signaling promotes osteoblast differentiation from preosteoblasts. . 2015 Jun 19;10(6):e0130627.
Jng MF, g HLong, en J. TOJ Cell Biochem3. Huang Z, Wang W, Ma J, Li B, , Yang H. mTOR signaling pathway differently regulates central and peripheral axon regeneration. . 2017 Jun; 28:1-7.
*Chen J.Pharmacological inhibition of S6K1 impairs self-renewac differentiation of bone marrow stromal cells. . .
MaYX, Wang XL, , Li B, Hur EM,Saijilafu. Front Mol Neurosci2017 Nov 28;10:391.
Chen J*. mTOR signaling in skeletal development and disease. Bone Research, 2018 Jan 30;6:1. doi: 10.1038/s41413-017-0004-5.
7 Zheng Y, Liu C, Ni L,Liu Z, Mirando A, Lin J, Saijilafu, Chen D, Chen J2018 Jul;233(7):5431-5440.
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Osteocyte-intrinsic mTORC1 signaling restrains trabecular bone accrual in mice. J Cell Biochem. 2018 Nov;119(11):8743-8749.9. A dual role of cholesterol in osteogenic differentiation of bone marrow stromal cells. Li K, Xiu C, Zhou Q, Ni L, Du J, Gong T, Li M, Saijilafu, Yang H, Chen J*. J Cell Physiol. 2018 Oct 14. doi: 10.1002/jcp.27635. [Epub ahead of print]
10. Proinflammatory macrophages promote degenerative phenotypes in rat nucleus pulpous cells partly through ERK and JNK signaling.Ni L, Zheng Y, Gong T, Xiu C, Li K, Saijilafu, Li B, Yang H*, Chen J*. J Cell Physiol. 2018 Oct 26. doi: 10.1002/jcp.27507. [Epub ahead of print]
加入苏州大学前的研究论文:
1. Shi Y, Chen J, Karner CM, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc atl Acad Sci U S A. 2015; 112(15):4678-83.
2. Dong Y, Long T, Wang C, Mirando AJ, Chen J, O’Keefe RJ, Hilton, MJ. NOTCH-mediated maintenance and expansion of human bone marrow stromal/stem cells: A technology designed for orthopaedic regenerative medicine. Stem Cells Transl Med. 2014; 3(12):1456-66.
3. Chen J, Holguin N, Shi Y, Silva M, Long F. mTORC2 signaling promotes skeletal growth and bone formation in mice. J Bone Miner Res. 2015; 30(2):369-78.
4. Gu S, Wu W, Liu C, Yang L, Sun C, Ye W, Li X, Chen J, Long F, Chen Y. BMPRIA mediated signaling is essential for temporomandibular joint development in mice. PLoS One. 2014 Aug 5; 9(8):e101000.
5. Chen J, Long F. mTORC1 signaling critically controls skeletal growth through stimulation of protein synthesis. Development. 2014 Jul; 141(14):2848-54.
6. Chen J, Tu X, Esen E, Joeng K, Lin C, Arbeit J, Rüegg M, Hall M, Ma L, Long F. WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014; 10(1): e1004145.
7. Chen J, Shi Y, Regan J, Karuppaiah K, Ornitz DM, Long F. Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice. PLoS One. 2014 Jan 15;9(1):e85161.
8: Esen E, Chen J, Karner CM, Okunade AL, Patterson BW, Long F. WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. Cell Metab. 2013 May 7;17(5):745-55.
9. Zheng D, Decker KF, Zhou T, Chen J, Qi Z, Jacobs K, Weilbaecher KN, Corey E, Long F, Jia L. Role of WNT7B-induced noncanonical pathway in advanced prostate cancer. Mol Cancer Res. 2013 May;11(5):482-93.
10. Chen J, Long F. β-catenin promotes bone formation and suppresses bone resorption in postnatal growing mice. J Bone Miner Res. 2013 May;28(5):1160-9.
11. Tu X, Chen J, Lim J, Karner CM, Lee SY, Heisig J, Wiese C, Surendran K, Kopan R, Gessler M, Long F. Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1. PLoS Genet.
2012;8(3):e1002577.
12. Chen J, Lan Y, Baek JA, Gao Y, Jiang R. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol. 2009 Oct 1;334(1):174-85
13. Chen J, Bush JO, Ovitt CE, Lan Y, Jiang R. The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival.Genesis. 2007 Aug;45(8):482-6.
14. Chen JQ, Dong Y, Wang YJ, Liu Q, Zhang JS, Chen SY. An AP2/EREBP-type transcription-factor gene from rice is cold-inducible and encodes a nuclear-localized protein. Theor Appl Genet. 2003 Oct;107(6):972-9.
15. He X, Chen J, Zhang Z, Zhang J, Chen S. Identification of salt-stress responsive genes in rice (Oryza sativa L.) by cDNA array. Sci China C Life Sci. 2002 Oct;45(5):477-84.
16. Karuppaiah K, Yu K, Lim J, Chen J, Smith C, Long F, Ornitz DM. FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth. Development. 2016 May 15;143(10):1811-22.
17. Liu Z, Chen J, Mirando AJ, Wang C, Zuscik MJ,O'Keefe RJ, Hilton MJ.A dual role for NOTCHsignaling in joint cartilage maintenance andosteoarthritis. Sci Signal . 2015 Jul 21;8(386):ra71.