个人信息
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文本框:Education Background：


Institute of Forensic Medicine, 2011.09 – 2014.06

Soochow University;

        Ph.D. in Department of Forensic Medicine.

lInstitute of Forensic Medicine, 2006.09 - 2009.07

China Medical University;

Masters in Department of Forensic Medicine.

文本框:Professional Experience:


Department of Forensic Medicine, Soochow University, 2015.01- present

Jiangsu Province,  China

Associate Professor


Department of Cell Biology and Neuroscience, Rutgers University, 2017.04- 2018.10

Piscataway, NJ

Postdoctoral Associate


College of Pharmaceutical Sciences, Soochow University, 2015.01- 2017.01

Jiangsu Province,  China

Postdoctoral Associate

文本框:Awards and Scholarship::


lThe annual Outstanding Paper Award for 2012-2013 (Suzhou government)2015

lIBRO/APRC perfect attendance award (IBRO/APRC School)2014

lThe eighth annual Outstanding Paper Award (Nantong government)2014


文本框:Publications and Conference:resentations::


lPublication:

(1)     Zhang Jiaxin, Li Sunao, Yang Zhenbei, Liu Chao, Chen Xueshi, Zhang Yuqi, Zhang Feng, Shi Haibin, Chen Xiping, Tao Luyang, Shan Haiyan and Zhang Mingyang. Implantation of injectable SF hydrogel with sustained hydrogen sulfide delivery reduces neuronal pyroptosis and enhances functional recovery after severe intracerebral hemorrhage. Biomaterials Advances 2022: 212743. （Corresponding Author，Top Journal）

(2)     Zhu Mingrui, Huang Xinqi, Shan Haiyan, Zhang Mingyang. Silk Fibroin Hydrogels Could be Therapeutic Biomaterials for Neurological Diseases. Oxid Med Cell Longev. 2022, 2076680. （Corresponding Author）

(3)     Zhang Yuqi, Fang Jing, Ye Shuyue, Zhao Yan, Wang Anna, Mao Qiulian, Cui Chaoxiang, Feng Yali, Li Jiachen, Li Sunao, Zhang Mingyang, Shi Haibin. A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy. Nat Commun. 2022 Mar 30;13(1):1685. （Top Journal）

(4)     Jeong Yu Young, Han Sinsuk, Jia Nuo, Zhang Mingyang#, Sheshadri Preethi, Tammineni Prasad, Cheung Jasmine, Nissenbaum Marialaina, Baskar Sindhuja S, Kwan Kelvin, Margolis David J, Jiang Peng, Kusnecov Alexander, Cai Qian. Broad activation of the Parkin pathway induces synaptic mitochondrial deficits in early tauopathy. Brain. 2022, 29;145(1):305-323.. （Top Journal）

(5)     Han Sinsuk, Zhang Mingyang#, Jeong Yu Young, Margolis David J, Cai Qian. The role of mitophagy in the regulation of mitochondrial energetic status in neurons. Autophagy. 2021, 5:1-20.（Top Journal）

(6)     Li Sunao, Zhang Jiaxin, Liu Chao, Wang Qianliang, Yan Jun, Hui Li, Jia Qiufang, Shan Haiyan, Tao Luyang, Zhang Mingyang#. The Role of Mitophagy in Regulating Cell Death. Oxidative Medicine and Cellular Longevity. 2021（Corresponding Author）

(7)     Zhang Jiaxin, Zhang Shaoyi, Shan Haiyan, Zhang Mingyang#, Biologic Effect of Hydrogen Sulfide and Its Role in Traumatic Brain Injury. Oxidative Medicine and Cellular Longevity. 2020, 2020: 10.（Corresponding Author）

(8)     Zhang Jiaxin, Shan Haiyan, Tao Luyang, Zhang Mingyang. Biological Effects of Hydrogen Sulfide and Its Protective Role in Intracerebral Hemorrhage. J Mol Neurosci. 2020, 70, 2020–2030. （Corresponding Author）

(9)     Zhang Jiaxin, Shi Chaoqun, Wang Haochen, Gao Cheng, Chang Pan, Chen Xiping, Shan Haiyan, Zhang Mingyang, Tao Luyang. Protective Effects of Hydrogen Sulfide on a Cell Culture Model of Traumatic Scratch Injury involving Suppression of Oxidative Stress and Upregulation of Nrf-2. Int J Biochem Cell Biol. 2019, 117:105636. （Corresponding Author）

(10)  Shan Haiyan, Qiu Jiping, Chang Pan, Chu Yang, Gao Cheng, Wang Haocheng, Chen Guang, Luo Chengliang, Wang Tao, Chen Xiping, Zhang Mingyang, Tao Luyang. Exogenous Hydrogen Sulfide Offers Neuroprotection on Intracerebral Hemorrhage Injury Through Modulating Endogenous H2S Metabolism in Mice. Front. Cell. Neurosci. 2019, 13: 349. （Corresponding Author）

(11)  Cheng Gao, Chang Pan, Yang Lijun, Wang Yi, Zhu Shaoua, Shan Haiyan, Zhang Mingyang, Tao Luyang. Neuroprotective Effects Of Hydrogen Sulfide On Sodium Azide-Induced Oxidative Stress In PC12 Cells. Int J Mol Med. 2018, 41(1):242-250. （Corresponding Author）

(12)  Zhang Mingyang, Shan Haiyan, Chang Pan,Ma Lu, Chu Yang, Shen Xi, Wu Qiong, Wang Zufeng, Luo Chengliang, Wang Tao, Chen Xiping, Tao Luyang,Upregulation of 3-MST Relates to Neuronal Autophagy After Traumatic Brain Injury in Mice, Cell Mol Neurobiol, 2017, 37(2):291-302.（Corresponding Author）

(13)  Shan Haiyan, ChuYang, Chang Pan, Wu Qiong, Wang Zufeng, Luo chengliang, Wang Tao, Zhu Shaoua, Zhang Mingyang, Tao Luyang. Neuroprotective Effects of Hydrogen Sulfide on Sodium Azide-Induced autophagic cell death in PC12 Cells, Molecular Medicine Reports, 2017, 16(5):5938-5946. （Corresponding Author）

(14)  Zhang Mingyang, Chen Xiping*, Tao Luyang*. Hydrogen sulfide offers neuroprotection on traumatic brain injury in mice through modulation of apoptosis- and autophagy-regulating molecules. Nitric Oxide, 2015,47:S21.

(15)  Zhang Mingyang, Chen Xiping*, Tao Luyang*. Hydrogen sulfide reduces histopathology and improves functional outcome after traumatic brain injury in mice. Nitric Oxide, 2015,47:S21.

(16)  Zhang Mingyang, Shan Haiyan, Chang Pan, Wang Tao, Dong Wenwen, Chen Xiping, Tao Luyang. Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in parallel with reduced apoptosis and autophagy in Mice. Plos one. 2014, 9(1):e87241.

(17)  Zhang Mingyang, Shan Haiyan, Wang Yaoqi, Wang Tao, Liu Weili, Wang Long, Zhang Lu, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. The expression changes of cystathionine-beta-synthase in brain cortex after traumatic brain injury. J Mol Neurosci. 2013, 511:57-67.

(18)  Zhang Mingyang, Shan Haiyan, Wang Tao, Liu Weili, Wang Yaoqi, Wang Long, Zhang Lu, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. Dynamic change of hydrogen sulfide after traumatic brain injury and its effect in mice. Neurochemical research. 2013, 384:714-25.

(19)  Zhang Mingyang, Shan Haiyan, Gu Zhenyong, Wang Donglin, Wang Tao, Wang Zhiwei, Tao Luyang. Increased expression of Calcium/calmodulin-dependent protein kinase type II subunit delta after rat traumatic brain injury [J]. J Mol Neurosci ,2012, 46:631-643.

(20)  Chang Pan, Zhang Mingyang*, Zhang Xiaomeng, et al. B-type natriuretic peptide attenuates endoplasmic reticulum stress in H9c2 cardiomyocytes underwent hypoxia/reoxygenation injury under high glucose/high fat conditions. Peptides. 2019 111:103-111. Co-author

(21)  Gao Yuan, Zhang Mingyang*, Wang Tao, Fan Yanyan, Yu Linshe, Ye Guanghua, Wang Zufeng Gao Cheng, Wang Haochen Luo Chengliang and Tao Luyang. IL-33/ST2L Signaling Provides Neuroprotection Through Inhibiting Autophagy, Endoplasmic Reticulum Stress, and Apoptosis in a Mouse Model of Traumatic Brain Injury. Front. Cell. Neurosci. 12:95. 2018, doi: 10.3389/fncel.2018.00095  Co-first author

(22)  Wang Tao, Huang Ya, Zhang Mingyang*, Wang Long, Wang Yaoqi, Zhang Lu, Dong Wenwen, Chang Pan, Wang Zufeng, Chen Xiping, Tao Luyang. [Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3β inhibition in a mouse model of intracerebral hemorrhage. Behavioural brain research. 2013, 247:132-139. Co-first author

(23)  Chang Pan, Dong Wenwen, Zhang Mingyang*, Wang Zufeng, Wang Yaoqi, Wang Tao, Gao Yuan, Meng Huanhuan, Luo Bing, Luo Chenliang, Chen Xiping, Tao Luyang. Anti-Necroptosis Chemical Necrostatin-1 Can Also Suppress Apoptotic and Autophagic Pathway to Exert Neuroprotective Effect in Mice Intracerebral Hemorrhage Model. J Mol Neurosci.2014, 52(2):242-249. Co-first author

(24)  Shan Haiyan, Guo Xiaofeng, Zhang Mingyang*.Effect of LPS on expressions of TNF-α, CD11b and IL-1β in BV_2 cells .Jiangsu Medical Journal. 2012, 38(20):2373-2375. [Article in Chinese]

(25)  Zhang Mingyang, Shan Haiyan, Xu Dongdong.The analysis of mtDNA polymorphisms using the PCR-RFLP technique[J]. Chinese Journal of Forensic Medicine.2011,26(1):49-51. [Article in Chinese]

(26)  Zhang Mingyang, Shan Haiyan, Xu Dongdong. The analysis of mitochondrial DNA polymorphism by PCR-SSCP and its application in forensic medicine. Journal of China Medical University. 2011, 40(4): 334-336. [Article in Chinese]

文本框:Received research grants::


(1)2018/04-2020/04 Shanghai Key Lab of Forensic Medicine Funded Project (Grant No. KF1801)

(2)2017/01-2019/12 The protecting role and mechanisms of hydrogen sulfide on neurons damage after intracerebral hemorrhage injury in severe pre-eclampsia mice, supported by National Natural Science Foundation of China (Grant No. 81601306)

(3)2016/04-2018/04 Key Laboratory of Evidence Science(China University of Political Science and Law)，Ministry of Education (Grant No. 2016KFKT05)

(4)2015/04-2017/04 Shanghai Key Lab of Forensic Medicine Funded Project (Grant No. KF1502)

(5)2015/01-2017/01 China Postdoctoral Science Foundation Funded Project (Grant No.2015M570476)

(6)2014/01-2016/12 The Protecting Role and Mechanisms of Hydrogen Sulfide on Neurons Damage after Traumatic Brain Injury, supported by National Natural Science Foundation of China (Grant No. 81301039)


研究领域
基本信息
头像




Mingyang Zhang

职称：Professor

院部/部门：Institute of Forensic medicine

学历：PhD, MD

学位：

毕业学校：Soochow University

毕业专业：Forensic medicine

联系方式

通讯地址：178 Ganjiang East Road, Suzhou, China.

邮政编码： 215021

电子邮箱：mingyangzhang@suda.edu.cn

联系电话：

传真号码：

办公地点：

科学研究
科研团队
论文

  1. Gao Cheng, Wang Haochen, Wang Tao, Luo Chengliang, Wang Zufeng, Zhang Mingyang, Chen Xiping and Tao Luyang. Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury. J Neurochem. 2020, doi: 10.1111/jnc.14983.

  2. Chang Pan, Zhang Xiaomeng, Zhang Mingyang, Li Guohua, Hu Lang, Zhao Huishou, Zhu Xiaoxing, Wu Juan, Wang Xihui, Wang Kaiyan, Zhang Jing, Ren Minggang, Chen Baoying, Zhu Xiaoling, Zhu Miaozhang and Yu Jun. Swimming exercise inhibits myocardial ER stress in the hearts of aged mice by enhancing cGMPPKG signaling. Mol Med Rep. 2020, 21(2): 549-556.

  3. Zhang Jiaxin, Shi Chaoqun, Wang Haochen, Gao Cheng, Chang Pan, Chen Xiping, Shan Haiyan, Zhang Mingyang, Tao Luyang. Hydrogen sulfide protects against cell damage through modulation of PI3K/Akt/Nrf2 signaling. Int J Biochem Cell Biol. 2019,117:105636. （Corresponding Author）

  4. Shan Haiyan, Qiu Jiping, Chang Pan, Chu Yang, Gao Cheng, Wang Haocheng, Chen Guang, Luo Chengliang, Wang Tao, Chen Xiping, Zhang Mingyang, Tao Luyang. Exogenous Hydrogen Sulfide Offers Neuroprotection on Intracerebral Hemorrhage Injury Through Modulating Endogenous H2S Metabolism in Mice. Front. Cell. Neurosci. 2019,13:349. （Corresponding Author）

  5. Chang Pan, Zhang Mingyang, Zhang Xiaomeng, et al. B-type natriuretic peptide attenuates endoplasmic reticulum stress in H9c2 cardiomyocytes underwent hypoxia/reoxygenation injury under high glucose/high fat conditions. Peptides. 2019,111:103-111. (Co-first author)

  6. Gao Yuan, Zhang Mingyang, Wang Tao, Fan Yanan, Yu Linse, Ye Gehua, Wang Zufeng, Gao Cheng, Wang Haocheng, Luo Chengliang and Tao Luyang. IL-33/ST2L Signaling Provides Neuroprotection Through Inhibiting Autophagy, Endoplasmic Reticulum Stress, and Apoptosis in a Mouse Model of Traumatic Brain Injury. Front. Cell. Neurosci. 2018, 12:95. (Co-first author)

  7. Cheng Gao, Chang Pan, Yang Lijun, Wang Yi, Zhu Shaoua, Shan Haiyan, Zhang Mingyang, Tao Luyang. Neuroprotective effects of hydrogen sulfide on sodium azide-induced oxidative stress in PC12 cells. Int J Mol Med. 2018, 41(1):242-250.(Corresponding Author)

  8. Shan Haiyan, Chu Yang, Wu Qiong, Wang Zufeng, Luo Chengliang, Wang Tao, Zhu Shaohua, Zhang Mingyang, Tao Lulang. Neuroprotective Effects of Hydrogen Sulfide on Sodium Azide-Induced autophagic cell death in PC12 Cells, Molecular Medicine Report. 2017, 16(5):5938-5946.(Corresponding Author)

  9. Zhang Mingyang, Shan Haiyan, Chang Pan, Ma Lu, Chu Yang, Shen Xi, Wu Qiong, Wang Zufeng, Luo Chengliang, Wang Tao, Chen Xiping, Tao Lulang* Upregulation of 3-MST Relates to Neuronal Autophagy After Traumatic Brain Injury in Mice. Cell Mol Neurobiol. 2017, 37(2):291-302. (Corresponding Author)

  10. Zhang Mingyang, Chen Xiping, Tao Luyang. Hydrogen sulfide offers neuroprotection on traumatic brain injury in mice through modulation of apoptosisand autophagy-regulating molecules. Nitric Oxide, 2015,47:S21.

  11. Zhang Mingyang, Chen Xiping, Tao Luyang. Hydrogen sulfide reduces histopathology and improves functional outcome after traumatic brain injury in mice. Nitric Oxide, 2015,47:S21.

  12. Zhang Mingyang, Shan Haiyan, Chang Pan, Wang Tao, Dong Wenwen, Chen Xiping, Tao Luyang. Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in parallel with reduced apoptosis and autophagy in Mice. Plos one. 2014, 9(1): e87241.

  13. Chang Pan, Dong Wenwen, Zhang Mingyang*, Wang Zufeng, Wang Yaoqi, Wang Tao, Gao Yuan, Meng Huanhuan, Luo Bing, Luo Chenliang, Chen Xiping, Tao Luyang. Anti-Necroptosis Chemical Necrostatin-1 Can Also Suppress Apoptotic and Autophagic Pathway to Exert Neuroprotective Effect in Mice Intracerebral Hemorrhage Model. J Mol Neurosci.2014, 52(2):242-249. (Co-first author)

  14. Zhang Mingyang, Shan Haiyan, Wang Tao, Liu Weili, Wang Yaoqi, Wang Long, Zhang Lu, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. Dynamic change of hydrogen sulfide after traumatic brain injury and its effect in mice. Neurochemical research. 2013, 38(4):714-25.

  15. Zhang Mingyang, Shan Haiyan, Wang Yaoqi, Wang Tao, Liu Weili, Wang Long, Zhang Lu, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. The expression changes of cystathionine-beta-synthase in brain cortex after traumatic brain injury. J Mol Neurosci. 2013, 51(1):57-67.

  16. Wang Tao, Huang Ya, Zhang Mingyang*, Wang Long, Wang Yaoqi, Zhang Lu, Dong Wenwen, Chang Pan, Wang Zufeng, Chen Xiping, Tao Luyang. [Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3β inhibition in a mouse model of intracerebral hemorrhage. Behavioural brain research. 2013, 247:132-139. (Co-first author)

  17. Zhang Mingyang, Shan Haiyan, Gu Zhenyong, Wang Donglin, Wang Tao, Wang Zhiwei, Tao Luyang. Increased expression of Calcium/calmodulin-dependent protein kinase type II subunit delta after rat traumatic brain injury [J]. J Mol Neurosci, 2012, 46:631– 643.                        

  18. Wang Tao, Zhang Lu, Zhang Mingyang, Bao Haijun, Liu Weili, Wang Yaoqi, Wang Long, Dai Dingkun, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. [Gly14]-Humanin reduces histopathology and improves functional outcome after traumatic brain injury in mice. Neuroscience. 2013, 12;231:70-81.

  19. Bao Haijun, Wang Tao, Zhang Mingyang, Liu Rui, Dai Dingkun, Wang Yaoqi, Wang Long, Zhang Lu, Gao Yuzhen, Qin, Zhenhong, Chen Xiping, Tao Luyang. Poloxamer-188 attenuates TBI-induced blood-brain barrier damage leading to decreased brain edema and reduced cellular death. Neurochemical research. 2012, 37(12):2856-67.

  20. Wang Yaoqi, Wang Long, Zhang Mingyang, Wang Tao,Bao Haijun,Liu Weili, Dai Dingkun, Zhang Lu, Chang Pan, Dong Wenwen, Chen Xiping, Tao Luyang. Necrostatin-1 suppresses autophagy and apoptosis in mice traumatic brain injury model. Neurochemical research. 2012, 37(9), 1849-1858.

  21. Shan Haiyan, Guo Xiaofeng, Zhang Mingyang*.Effect of LPS on expressions of TNF-α, CD11b and IL-1β in BV_2 cells .Jiangsu Medical Journal. 2012, 38(20):2373-2375. [Article in Chinese]

  22. Zhang Mingyang, Shan Haiyan, Xu Dongdong.The analysis of mtDNA polymorphisms using the PCR-RFLP technique[J]. Chinese Journal of Forensic Medicine.2011,26(1):49-51. [Article in Chinese]

  23. Zhang Mingyang, Shan Haiyan, Xu Dongdong. The analysis of mitochondrial DNA polymorphism by PCR-SSCP and its application in forensic medicine. Journal of China Medical University. 2011, 40(4): 334-336. [Article in Chinese]


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