论文发表：
https://publons.com/researcher/3076578/hua-wu/
一、代表性学术成果：
1、Wu H*, Yang TY, Li Y, Ye W, Liu F, He XS, Wang JR, Gan WJ, Li XM, Zhang S, Zhao YY, Li JM*. TRAF6 promotes hepatocarcinogenesis by interacting with HDAC3 to enhance c-Myc gene expression and protein stability. Hepatology. 2019.（第一作者/共同通讯作者，IF: 14.971）
2、Wu H, Lu XX, Wang JR, Yang TY,Li XM, He XS,Li Y, Ye WL,Wu Y, Gan WJ, Guo PD, Li JM*. TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation. Autophagy. 2019 Feb 26. (第一作者，IF: 11.059)
3、Ye XH#, Wu H#, Sheng LY, Liu YX, Ye F, Wang M, Zhou H, Su Y, Zhang XK*, Oncogenic potential of truncated RXR during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling. Nature Communications. 2019 Apr 1;10(1):1463.(共同第一作者，IF: 11.878）
4、Wu H#, Yao S#, Zhang S, Wang JR, Guo PD, Li XM, Gan WJ, Mei L, Gao TM*, Li JM*. Elevated expression of Erbin destabilizes ERα protein and promotes tumorigenesis of hepatocellular carcinoma. Journal of Hepatology. 2017Jun;66(6):1193-1204. (第一作者，IF : 18.946）
5、Guo PD#, Lu XX#, Gan WJ#, Li XM#, He XS, Zhang S, Ji QH, Zhou F, Cao Y, Wang JR, Li JM*, Wu H*.RARγ downregulation contributes to colorectal tumorigenesis and metastasis by de-repressing the Hippo-Yap pathway. Cancer Research.2016 Jul 1;76(13):3813-25. (通讯作者，IF:8.378）
6、Gan WJ#, Wang JR#, Zhu XL#, He XS, Guo PD, Zhang S, Li XM, Li JM*, Wu H*. RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis. J Exp Clin Cancer Res. 2016 Oct 19;35(1):164. (通讯作者，IF:5.646）
7、Wu H#, Li XM#, Wang JR, Gan WJ, Jiang FQ, Liu Y, Zhang XD, He XS, Zhao YY, Lu XX, Guo YB, Zhang XK*, Li JM*.NUR77 exerts a protective effect against inflammatory bowel disease by negatively regulating the TRAF6/TLR-IL-1R signalling axis. Journal of pathology. 2016 Feb;238(3):457-69.(第一作者，IF:5.942）
8、Xing C, Lu XX, Guo PD, Shen T, Zhang S, He XS, Gan WJ, Li XM, Wang JR, Zhao YY, Wu H*, Li JM*.Ubiquitin Specific Protease 4 (USP4)-mediated Deubiquitination and Stabilization of PRL-3 is Required for Potentiating Colorectal Oncogenesis.Cancer Research. 2016 Jan 1;76(1):83-95. (共同通讯作者，IF : 8.378）
9、Yao S#, Zheng P#, Wu H#, Song L, Ying X, Xing C, Li Y, Xiao Z, Zhou X, Shen T, Chen L, Liu Y, Lai M, Mei L, Gao T*, Li J*.Erbin interacts with c-Cbl and promotes tumourigenesis and tumour growth in colorectal cancer by preventing c-Cbl mediated ubiquitination and down-regulation of EGFR. Journal of pathology. 2015 May;236(1):65-77. (共同第一作者，IF:5.942）
10、Wang JR#, Gan WJ#, Li XM#, Zhao YY, Li Y, Lu XX,Li JM*,Wu H*.Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin. Carcinogenesis.2014 Nov;35(11):2474-84. (通讯作者，IF:4.004）
11、Wu H, Lin YY, Li WG, Sun Z, Gao WW, Zhang HP, Xie L, Jiang FQ, Qin B, Yan TD, Chen LQ, Zhao Y, Cao X, Wu Y, Lin BZ, Zhou H, Wong AS,, Zhang XK*, Zeng JZ*. Regulation of Nur77 Expression by b-catenin and Its Mitogenic Effect in Colon Cancer Cells. FASEB J. 2011 Jan;25(1):192-205. (第一作者，IF:5.391）
12、Yan TD#, Wu H#, Zhang HP#, Lu N, Ye P, Yu FH, Zhou H, Li WG, Cao X, LinYY, He JY, Gao WW, Zhao Y, Xie L, Chen JB, Zhang XK*，Zeng JZ*. Oncogenic potential of retinoic acid receptor-gamma in hepatocellular carcinoma. Cancer Research. 2010 Mar 15;70(6):2285-95. (共同第一作者，IF:8.378）
二、近些年发表的其他学术论文：
1、Xu Y, Xu H, Li M, Wu H, Guo Y, Chen J, Shan J, Chen X, Shen J, Ma Q, Liu J, Wang M, Zhao W, Hong J, Qi Y, Yao C, Zhang Q, Yang Z, Qian C, Li J.KIAA1199 promotes sorafenib tolerance and the metastasis of hepatocellular carcinoma by activating the EGF/EGFR-dependent epithelial-mesenchymal transition program. Cancer Lett. 2019 Jul 10;454:78-89.
2、He XS#, Guo LC#, Du MZ#, Huang S, Huang RP, Zhan SH, Gu DM, Liu WS, Wang XM, Wu H*, Gan WJ*. The Long Non-coding RNA NONHSAT062994 Inhibits Colorectal Cancer by Inactivating Akt Signaling. Oncotarget. 2017 Aug 2;8(40):68696-68706. (通讯作者)
3、Li XM#, Yang TY#, He XS#, Wang JR, Gan WJ, Zhang S, Li JM*, Wu H*. Orphan nuclear receptor Nur77 inhibits Poly (I:C)-triggered acute liver inflammation by inducing the ubiquitin-editing enzyme A20. Oncotarget. 2017 May 9;8(37):61025-61035.(通讯作者)
4、Li XM#, Wang JR#, Shen T#, Gao SS, He XS, Li JN, Yang TY, Zhang S, Gan WJ, Li JM*, Wu H*. Nur77 deficiency in mice accelerates tumor invasion and metastasis by facilitating TNFα secretion and lowering CSF-1R expression. PLoS One. 2017 Feb 7;12(2):e0171347. (通讯作者)
5、Li XM#, Zhang S#, He XS#, Guo PD, Lu XX, Wang JR, Li JM, Wu H*. Nur77-mediated TRAF6 signalling protects against LPS-induced sepsis in mice. J Inflamm (Lond). 2016 Feb 2;13:4. (通讯作者)
6、Li XM#, Lu XX#, Xu Q, Wang JR, Zhang S, Guo PD, Li JM, Wu H*. Nur77 deficiency leads to systemic inflammation in elderly mice. J Inflamm (Lond). 2015 Jun 26;12:40. (通讯作者)
7、 Sun Z, Cao X, Jiang MM, Qiu Y, Zhou H, Chen L, Qin B, Wu H, Jiang F, Chen J, Liu J, Dai Y, Chen HF, Hu QY, Wu Z, Zeng JZ, Yao XS, Zhang XK*.Inhibition ofβ-catenin Signaling by Nongenomic Action of Orphan Nuclear Receptor Nur77.Oncogene, 2012 May 24;31(21):2653-67 .
8、 Lu N, Liu J, Liu J, Zhang C, Jiang F, Wu H, Cao X, Yan T, Wang G, Zhou H, Lin BZ, Yan XM, Zhang XK*, Zeng JZ*. Antagonist Effect of Triptolide on AKT Activation by Truncated Retinoid X Receptor-alpha. PLOS One. 2012;7(4):e35722.
9、 Zhou H#, Liu W#, Su Y, Wei Z, Liu J, Kolluri SK, Wu H, Cao Y, Chen J, Wu Y, Yan T, Cao X, Gao W, Molotkov A, Jiang F, Li W-G, Lin B, Zhang H-P, Yu J, Luo S-P, Zeng J-Z, Duester G, Huang P-Q, ZhangXK*.NSAID Sulindac and Its Analogs Bind RXRalpha and Inhibit RXRalpha-dependent AKT Signaling. Cancer Cell , 2010 Jun 15;17(6):560-73.
10、Han YH, Zhou H, Kim JH, Yan TD, Lee KH, Wu H, Lin F, Lu N, Liu J, Zeng JZ, Zhang XK.A unique cytoplasmic localization of retinoic acid receptor-gamma and its regulations.J Biol Chem. 2009 Jul 3;284(27):18503-14.
