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n Xu, C., Zhang, L., Wang, W., Tang, Y., Wang, Q., An, J., ... & Li, H. (2023). Improving the Circularization Efficiency, Stability and Translatability of Circular RNA by circDesign. bioRxiv, 2023-07. |
n Fan T#, Xu C# (co-first author), Wu J#, Cai Y, Cao W, Shen H, Zhang M, Zhu H, Yang J, Zhu Z, Ma X, Ren J, Huang L, Li Q, Tang Y, Yu B, Chen C, Xu M, Wang Q, Xu Z, Chen F, Liang S, Zhong Z, Jamroze A, Tang DG, Li H, Dong C. Lipopolyplex-formulated mRNA cancer vaccine elicits strong neoantigen-specific T cell responses and antitumor activity. Sci Adv. 2024 Oct 11;10(41):eadn9961. doi: 10.1126/sciadv.adn9961. |
n Cui G, Shao Y, Wang J, Xu C*, Jinping Zhang*, Zhiyuan Zhong*, Polymersome-mediated Cbl-b silencing activates T cells against solid tumors. Biomater. Sci., 2025, doi:10.1039/D5BM00001G |
n Xu C, Yin H, Yudhistira T, Li Z, Binzel D,*Guo P*, Conversion of Chemical Drugs into Targeting Ligands on RNA Nanoparticles and Assessing Payload Stoichiometry for Optimal Biodistribution in Cancer Treatment. RNA NanoMed, 2024, (1) 109-123.doi:10.59566/ISRNN.2024.0101109. |
n Zhang, H.#, Zhang, L.#, Lin, A. #, Xu, C. # (co-first author), Li, Z., Liu, K., ... & Huang, L. (2023). Algorithm for optimized mRNA design improves stability and immunogenicity. Nature, 1-3. |
n Yi Fang, Jing-Xin Li, Davone Duangdany, Yang Li, Xi-Lin Guo, Chanthala Phamisith, Ming-Yun Shen, Bo Yu, Bin Luo, Yu-Zhu Wang, Si-Jun Liu, Fan-Fan Zhao, Cong-Cong Xu, Xu-Hui Qiu, Rong-Juan Pei, Jie Wang, Haifa Shen, Wu-Xiang Guan, Hang-Wen Li, Mayfong Mayxay, Safety, immunogenicity and efficacy of a modified COVID-19 mRNA vaccine, SW-BIC-213, in healthy people aged 18 years and above: interim report of a Phase 3 double-blinded, randomized, parallel controlled clinical trial in Lao PDR (Laos). EClinicalMedicine. 2023 Dec 13;67:102372. doi: 10.1016/j.eclinm.2023.102372. |
n Carcache PJ, Guo S, Li H, Zhang K, Xu C, Chiu W, Guo P. Regulation of reversible conformational change, size switching, and immunomodulation of RNA nanocubes. RNA. 2021 Sep 1;27(9):971-80. |
n Guo S., Xu C., Yin H., Hill J., Pi F., Guo P. (2019). Tuning the size, shape and structure of RNA nanoparticles for favorable cancer targeting and immunostimulation. WIREs Nanomedicine and Nanobiotechnology, 2019 Aug 27:e1582. doi: 10.1002/wnan.1582 |
n Xu, C., Zhang, K., Yin, H., Li, Z., Krasnoslobodtsev, A., Zheng, Z., Ji, Z., Guo, S., Li, S., Chiu, W. and Guo, P., 2020. 3D RNA nanocage for encapsulation and shielding of hydrophobic biomolecules to improve the in vivo biodistribution. Nano Research, 13(12), pp.3241-3247. |
n Xu C., Yin H., Lingren H., Li Z., Guo P. 2022. Controlling the Multivalency of Methotrexate on RNA Nanoparticles for Optimized Cancer Targeting and Therapeutic Effect, Under Submission. |
n Xu C., Wang H., Yin H., Sechi M., Li Z., Kumar K., Tweedle M., Knopp M., Guo P. 2022. Small Molecule Conjugated RNA Nanoparticles for PET Imaging-guided Prostate Cancer Therapy, Under Submission. |
n Ghimire C, Wang H, Li H, Vieweger M, Xu C, Guo P. RNA nanoparticles as rubber for compelling vessel extravasation to enhance tumor targeting and for fast renal excretion to reduce toxicity. ACS Nano. 2020 Sep 9;14(10):13180-91. |
n Li H., Wang S., Ji Z., Xu C., Shlyakhtenko L.S. and Guo P., Construction of RNA nanotubes. 2019. Nano Research, 12(8), pp.1952-1958. |
n Zheng Z, Li Z, Xu C, Guo B, Guo P. Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping. J Control Release. 2019 Aug 22;. doi: 10.1016/j.jconrel.2019.08.021. |
n Yin H, Xiong G, Guo S, Xu C, Xu R, Guo P, Shu D. Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133. Mol Ther. 2019 Jul 3;27(7):1252-1261. doi: 10.1016/j.ymthe.2019.04.018. |
n Xu Y, Pang L, Wang H, Xu C, Shah H, Guo P, Shu D, Qian SY. Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo-γ-linolenic acid for colon cancer suppression. Redox Biol. 2019 Feb;21:101085. doi: 10.1016/j.redox.2018.101085. |
n Xu C, Li H, Zhang K, Binzel DW, Yin H, Chiu W, Guo P. Photo-controlled release of paclitaxel and model drugs from RNA pyramids. Nano Res. 2019 Jan;12(1):41-48. doi: 10.1007/s12274-018-2174-x. |
n Xu C, Haque F, Jasinski DL, Binzel DW, Shu D, Guo P. Favorable biodistribution, specific targeting and conditional endosomal escape of RNA nanoparticles in cancer therapy. Cancer Lett. 2018 Feb 1;414:57-70. doi: 10.1016/j.canlet.2017.09.043. |
n Li W, Yang X, He L, Wang K, Wang Q, Huang J, Liu J, Wu B, Xu C. Self-Assembled DNA Nanocentipede as Multivalent Drug Carrier for Targeted Delivery. ACS Appl Mater Interfaces. 2016 Oct 5;8(39):25733-25740. doi: 10.1021/acsami.6b08210. |
n Haque F†, Xu C†, Jasinski DL, Li H, Guo P. († Contributed equally) Using Planar Phi29 pRNA Three-Way Junction to Control Size and Shape of RNA Nanoparticles for Biodistribution Profiling in Mice. Methods Mol Biol. 2017;1632:359-380. doi: 10.1007/978-1-4939-7138-1_23. |
n Guo S, Xu C, Yin H, Guo P, Hill J, and Pi F. 2022. Tuning the Size, Shape, and Structure of RNA Nanoparticles for Favorable Cancer Targeting and Immunostimulation. RNA Nanotechnology and Therapeutics, pp.543-562. |
n 徐聪聪;唐钰莹;胡群;王纬云;李航文;一种新型环状RNA 及其制备方法以及治疗苯丙酮尿症的环状RNA 药物,申请号:2023103518562 |
n 方熠;王海丽;徐聪聪;王纬云;李航文;水痘-带状疱疹RNA 疫苗,申请号:202310351636X |
n 羊小海;李文山;何磊良;王青;王柯敏;黄晋;刘剑波;吴斌;徐聪聪;靶向载体,靶向药物及靶向药物的应用,靶向探针及靶向探针的应用,CN106267219B,2019 |
n Peixuan Guo; Daniel Jasinski; Hui Li; Emil Khisamutdinov; Congcong Xu; Self-assembled 3D RNA Cage Nanoparticles, PCT/US2017/032001 |
n Peixuan Guo; Satheesh Ellipilli; Hongzhi Wang; Congcong Xu; Xin Li; RNA Nanoparticle for Liver Cancer Treatment, 2020, PCT/US2020/065621 |