Yingbin Zhong Associate professor

2006-2011  Ph.D., Pharmaceutical Chemistry

                   School of Medicine and Pharmacy, Ocean University of China

2007-2009  Visiting Scholar

                    Department of Molecular, Cellular, and Developmental Biology

                     University of Michigan

2003-2006  M.S., Marine Biology

                    Department of Marine Biology

                    College of Marine Life Science, Ocean University of China

1998-2002  B.S., Aquiculture

                    Department of Aquiculture

2012- present   Associate Professor

                         Department of Genetics

                         School of Biology & Basic Medical Sciences, Soochow University

2010-2012        Lecturer

                         College of Fisheries and Life Science, Shanghai Ocean University

Circadian Rhythms

Metabolism

Disease model

Development

Medical Genetics

Biochemistry

Basic Biological Experiment

Biological Safety

NSFC (31871186), 01/01/2019 -12/31/2020

 “Mechanistic study of Grouch1 and Grouch2 on the zebrafish circadian clock”

NSFC (31200877), 01/01/2013 -12/31/2015

 “IGF-independent action of proteolytic fragments 1-98 and 1-212 of IGFBP-3 and its effect on BMP signaling”

1.  Miao Yang, Yan Liu, Zhilin Zhong, Yue Ou1, Mingyong Wang*, Yingbin Zhong*, Chao Liu*. Direct regulation of Per2 by Roraa: insights into circadian and metabolic interplay in zebrafish. Cell. Mol. Life Sci. 2025, 82:195. https://doi.org/10.1007/s00018-025-05696-8. (SCI, IF=6.259)

2.  Hao-yi Zhang, Ke-yun Li, Yi-li Wang, Chun-Jiao Wei, Yu-Xuan Gao, Ren-Zhoua, Ying-bin Zhong, Zong-jun Yin, Da-long Ren*. ROS regulates circadian rhythms by modulating Ezh2 interactions with clock proteins. Redox Biology, 2025, 81:103526. (SCI, IF=10.723)

3.  Yan Zhuang, Yantong Zhang, Chao Liu*, and Yingbin Zhong*. Interplay Between the Circadian Clock and Sirtuins. International Journal of Molecular Sciences, 2024, 25(21), 11469 (SCI, IF=4.932)

4.  Xuanxuan Bai#, Jianxin Jia#; Qi Kang, Yadong Fu, You Zhou, Yingbin Zhong*; Chao Zhang*, Mingyu Li*. Integrated metabolomics and lipidomics analysis reveal remodeling of amino acid metabolism and lipid metabolism in glucagon receptor deficient zebrafish. Frontiers in Cell and Developmental Biology, 2021, 8: 605979. (SCI, IF=6.684)

5.  Zeshan Lin#, Lei Chen#, Xianqing Chen#, Yingbin Zhong#, Yue Yang#, Wenhao Xia#, Chang Liu, Wenbo Zhu, Han Wang, Biyao Yan, Yifeng Yang, Xing Liu, Kjersti Sternang Kvie, Knut Håkon Røed, Kun Wang, Wuhan Xiao, Haijun Wei, Guangyu Li, Rasmus Heller, M. Thomas P. Gilbert, Qiang Qiu*, Wen Wang*, Zhipeng Li*.  Biological adaptations in the Arctic cervid, the reindeer (Rangifer tarandus). Science. 2019, 364(6446). doi: 10.1126/science.aav6312. (SCI, IF=41.846)

6.  Yunfeng Zhang, Haitang Qin, Yongjie Feng, Peng Gao, Yingbin Zhong, Yicheng Tan, Han Wang, Ying Xu, Joseph S. Takahashi, Guocun Huang*. CNOT1 mediates phosphorylation via Protein kinase A on the circadian clock. BioRxiv 630897. May 08, 2019. doi: https://doi.org/10.1101/630897.

7.  Yingbin Zhong, Qiang Ye, Chengyan Chen, Mingyong Wang, and Han Wang*.  Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish. Nucleic Acids Research. 2018, 46:7. 2282-2299. (SCI, IF=11.561).

8.  Yingbin Zhong and Cunming Duan*.  Lamprey IGF-Binding Protein-3 has IGF-Dependent and -Independent actions. Frontiers in Endocrinology. 2017, 7:174. doi: 10.3389/fendo.2016.00174. (SCI, IF=3.675).

9.  Bo Xiao, Tian-Ming Chen, Yingbin Zhong*.  Possible molecular mechanism underlying cadmium-induced circadian rhythms disruption in zebrafish. Biochemical and Biophysical Research Communications. 2016, 481:201-205. (SCI, IF=2.466).

10.  Lin Bo, Zhichun Liu, Yingbin Zhong, Jian Huang, Bin Chen, Han Wang*, Youjia Xu*.  Iron deficiency anemia’s effect on bone formation in zebrafish mutant. Biochemical and Biophysical Research Communications. 2016, 475:271-276. (SCI, IF=2.371).

11.  Mingyong Wang, Zhaomin Zhong, Yingbin Zhong, Wei Zhang and Han Wang*. The zebrafish Period2 protein positively regulates the circadian clock through mediation of RAR-related orphan receptor alpha (Rorα). Journal of Biological Chemistry. 2015, 290(7):4367-82. (SCI, IF=4.573).

12.  Fei Wang#, Guo-dong Huang#, Hui Tian, Ying-bin Zhong, Hui-juan Shi, Zheng Li, Xian-sheng Zhang, Han Wang*, Fei Sun*. Point mutations in KAL1 and the mitochondrial gene MT-tRNAcys synergize to produce Kallmann syndrome phenotype. Scientific Reports. 2015 Aug 17; 5:13050. doi: 10.1038/srep13050. (SCI, IF=5.228).

13. Yingbin Zhong, Ling Lu, Jianfeng Zhou, Yun Li, and Cunming Duan*. IGF binding protein-3 exerts its ligand-independent action by antagonizing BMP action in zebrafish embryos. Journal of Cell Science. 2011, 124:1925-1935. (SCI, IF=6.289).

14.  Boguang Sun, Xiao-Hua Zhang*, Xuexi Tang, Shushan Wang, Yingbin Zhong, Jixiang Chen, and Brian Austin. A Single Residue Change in Vibrio harveyi Hemolysin Results in the Loss of Phospholipase and Hemolytic Activities and Pathogenicity for Turbot (Scophthalmus maximus). Journal of Bacteriology. 2007, 189:2575-2579. (SCI, IF=4.013)

15. Yingbin Zhong, Xiao-Hua Zhang*, Jixiang Chen, Zhenghao Chi, Boguang Sun, Yun Li, and Brian Austin. Overexpression, purification, characterization and pathogenicity of Vibrio harveyi hemolysin VHH. Infection and Immunity. 2006, 74:6001-6005. (SCI, IF=4.004).

16.  L. Pang, X.-H. Zhang*, Y. Zhong, J. Chen, Y. Li, and B. Austin. Identification of Vibrio harveyi using PCR amplication of the toxR gene. Letters in Applied microbiology. 2006, 43:249-255. (SCI, IF=1.593)