1.Hali S, Kim K*, Zhang L*, Han DW* et al., Differentiation defect into GABAergic neurons in cerebral organoids from autism patients. CNS Neurosci Ther. 2025 Jun;31(6):e70449.

2.Cui J, Zhao G, Xie W, Yang Y, Fu X, Meng H, Liu H, Tan M, Chen D, Rong C, Wang Y, Wang Y*, Zhang L*. Exacerbated hepatotoxicity in in vivo and in vitro non-alcoholic fatty liver models by biomineralized copper sulfide nanoparticles. Biomater Adv. 2025 Mar;168:214117.

3.Yang Y, Tan M, Cui J, Liu H, Meng H, Cheng X, Wang Y, Wang Y, Zhang L*. Endocytic pathways and metabolic fate of colloidal bismuth subcitrate in human renal cells. Chem Biol Interact. 2024 Nov 1;403:111256.

4.Gu Y, Xu P, Wu Y, Li C, Shen J, Cheng X, Wang Y, Zhang L, Wang Y*, Gao M*. Mechanotransduction-Piloted Whole-Cell Vaccines for Spatiotemporal Modulation of Postoperative Antitumor Immunity. ACS Nano. 2024 Oct 22;18(42):28675-28690.

5.Zu H, Wu Y, Meng H, Cheng X, Wang Y, Zhang L*, Wang Y*. Tumor Metabolism Aiming Cu2-xS Nanoagents Mediate Photothermal-Derived Cuproptosis and Immune Activation. ACS Nano. 2024 Sep 3;18(35):23941-23957.

6.Yu H, Liu Z, Guo H, Hu X, Wang Y, Cheng X, Zhang L*, Wang Y*. Mechanoimmune-Driven Backpack Sustains Dendritic Cell Maturation for Synergistic Tumor Radiotherapy. ACS Nano. 2024 Aug 27;18(34):23741-23756.

7.Zhu W, Cheng X, Xu P, Gu Y, Xu H, Xu J, Wang Y, Zhang L, Wang Y. Radiotherapy-Driven Nanoprobes Targeting for Visualizing Tumor Infiltration Dynamics and Inducing Ferroptosis in Myeloid-Derived Suppressor Cells. J Am Chem Soc. 2024 Aug 14;146(32):22455-22468.

8.Xu P, Gu Y, Li C, Shen J, Cheng X, Zhang L, Wang Y, Wang Y. Radioactive Hydroxyapatite Microspheres Empower Sustainable In Situ Tumor Vaccination. ACS Nano. 2024 Jul 16;18(28):18425-18443.

9.Yu H, Wu Y, Xu J, Wang Y, Cheng X, Zhang L, Qin J, Wang Y. Neutrophils-mediated bioinspired nanoagents for noninvasive monitoring of inflammatory recruitment dynamics and navigating phototherapy in rheumatoid arthritis. Biomater Adv. 2024;158:213764.

10.Wu Y, Qin J, Gu Y, Zhao G, Xu P, Lin S, Cheng X, Zhang L, Wang Y, Wang Y. Radioresponsive Delivery of Toll-like Receptor 7/8 Agonist for Tumor Radioimmunotherapy Enabled by Core-Cross-Linked Diselenide Nanoparticles. ACS Nano. 2024;18(4):2800-2814.

11.Pang G, Chen P, Cao X, Yu H, Zhang L, Zhao J, Wang FJ. Improving combination cancer immunotherapy by manipulating dual immunomodulatory signals with enzyme-triggered, cell-penetrating peptide-mediated biomodulators. Biomater Sci. 2024;12(3):776-789.

12.Yang S, Wu Y, Cheng X, Zhang L, Yu Y, Wang Y, Wang Y. Harnessing astaxanthin-loaded diselenium cross-linked apotransferrin nanoparticles for the treatment of secretory otitis media. J Control Release. 2024;365:398-411.

13.Wang Y, Wu Y, Li L, Ma C, Zhang S, Lin S, Zhang L, Wang Y, Gao M. Chemotherapy-Sensitized In Situ Vaccination for Malignant Osteosarcoma Enabled by Bioinspired Calcium Phosphonate Nanoagents. ACS Nano. 2023;17(7):6247-6260.

14.Gu Y, Lin S, Wu Y, Xu P, Zhu W, Wang Y, Cheng X, Zhang L, Stauber RH, Wang Y, Gao M. Targeting STING Activation by Antigen-Inspired MnO2 Nanovaccines Optimizes Tumor Radiotherapy. Adv Healthc Mater. 2023;12(12):e2300028.

15.Guo H, Yu H, Zu H, Cui J, Ding H, Xia Y, Chen D, Zeng Y, Wang Y, Wang Y, Zhang L*. Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method. Toxicol Lett. 2023;383:64-74.

16.Gu Y, Lin S, Wu Y, Xu P, Zhu W, Wang Y, Cheng X, Zhang L, Stauber RH, Wang Y, Gao M. Targeting STING Activation by Antigen-Inspired MnO2 Nanovaccines Optimizes Tumor Radiotherapy. Adv Healthc Mater. 2023;12(12):e2300028.

17.Wang Y, Wu Y, Li L, Ma C, Zhang S, Lin S, Zhang L, Wang Y*, Gao M*. Chemotherapy-Sensitized In Situ Vaccination for Malignant Osteosarcoma Enabled by Bioinspired Calcium Phosphonate Nanoagents. ACS Nano. 2023;17(7):6247-6260.

18.Hao P, Wang Y, Sun X, Wang J, Zhang L*. Derivation of the toxicological threshold of silicon element in the extractables and leachables from the pharmaceutical packaging and process components. Toxicol Ind Health. 2022;38(12):819-834.

19.Yang L, Afshari MJ, Ge J, Kou D, Chen L, Zhou D, Li C, Wu S, Zhang L, Zeng J, Zhong J, Stauber RH, Gao M. Functionalized Ultrasmall Iron Oxide Nanoparticles for T1-Weighted Magnetic Resonance Imaging of Tumor Hypoxia. Molecules. 2022;27(20):6929.

20.Yu H, Guo H, Wang Y, Wang Y, Zhang L*. Bismuth nanomaterials as contrast agents for radiography and computed tomography imaging and their quality/safety considerations. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2022;14(6):e1801.

21.Zhang S, Wu Y, Yu J, Ma C, Wang Y, Wang Y, Li L*, Zhang L*. Gadolinium-Bisphosphonate Nanoparticle-Based Low-Dose Radioimmunotherapy for Osteosarcoma. ACS Biomater Sci Eng. 2022;8(12):5329-5337.

22.Gu J, Zhao G, Yu J, Xu P, Yan J, Jin Z, Chen S*, Wang Y, Zhang L, Wang Y*. Injectable pH-responsive hydrogel for combinatorial chemoimmunotherapy tailored to the tumor microenvironment. J Nanobiotechnology. 2022;20(1):372.

23.Xia YN, Zu H, Guo H, Jiang T, Yang S, Yu H, Zhang S, Ding H, Li X, Wang Y, Wang Y*, Zhang L*. Preclinical safety and hepatotoxicity evaluation of biomineralized copper sulfide nanoagents. Journal of Nanobiotechnology. 2022;20(1):185.

24.Yu H, Guo H, Ding H, Lin S, Wang Y, Zhang L*. Yong Wang*. Therapeutic Dendritic Cell Vaccines Engineered with Antigen-biomineralized Bi2S3 Nanoparticles for Personalized Tumor Radioimmunotherapy. Aggregate. 2022; 3(5): e194.

25.Klionsky DJ, Abdel-Aziz AK, Zhang L et al (over 2800 authors). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition,). Autophagy. 2021;17(1):1-382.

26.Pang G, Liu Y, Wang Y, Wang Y, Wang F, Zhao J, Zhang L*. Endotoxin contamination in ovalbumin as viewed from a nano-immunotherapy perspective. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021:e1747.

27.Jiang T, Guo H, Xia YN, Liu Y, Chen D, Pang G, Feng Y, Yu H, Wu Y, Zhang S, Wang Y, Wang Y, Wen H*, Zhang L*. Hepatotoxicity of copper sulfide nanoparticles towards hepatocyte spheroids using a novel multi-concave agarose chip method. Nanomedicine (Lond). 2021;16(17):1487-1504.

28.Wu Y, Gu J, Zhang S, Gu Y, Ma J, Wang Y*, Zhang L, Wang Y*. Iodinated BSA Nanoparticles for Macrophage-Mediated CT Imaging and Repair of Gastritis. Anal Chem. 2021;93(16):6414-6420.

29.Zhang X, Jiang T, Chen D, Wang Q, Zhang L*. Three-dimensional liver models: state of the art and their application for hepatotoxicity evaluation. Crit Rev Toxicol. 2020;50(4):279-309. 二区，

30.Pang G, Chen C, Liu Y, Jiang T, Yu H, Wu Y, Wang Y, Wang FJ*, Liu Z*, Zhang L*. Bioactive Polysaccharide Nanoparticles Improve Radiation-Induced Abscopal Effect through Manipulation of Dendritic Cells. ACS Appl Mater Interfaces. 2019;11(45):42661-42670.

31.Wang J, Chen XY, Zhao Y, Yang Y, Wang W, Wu C, Yang B, Zhang Z, Zhang L, Liu Y, Du X, Li W, Qiu L, Jiang P, Mou XZ, Li YQ*. pH-Switchable Antimicrobial Nanofiber Networks of Hydrogel Eradicate Biofilm and Rescue Stalled Healing in Chronic Wounds. ACS Nano. 2019;13(10):11686-11697.

32.Yu H, Yang Y, Jiang T, Zhang X, Zhao Y, Pang G, Feng Y, Zhang S, Wang F, Wang Y, Wang Y*, Zhang L*. Effective Radiotherapy in Tumor Assisted by Ganoderma lucidum Polysaccharide-Conjugated Bismuth Sulfide Nanoparticles through Radiosensitization and Dendritic Cell Activation. ACS Appl Mater Interfaces. 2019;11(31):27536-27547.

33.Cao Y, Huang H, Chen L, Du H, Cui J, Zhang L*, Lee B, Cao Q*. 2019. Enhanced Lysosomal Escape of pH-Responsive PEI-Betaine Functionalized Carbon Nanotube for the Co-delivery of Survivin siRNA and Doxorubicin. ACS Applied Materials & Interfaces 11(10):9763-9776.

34.Pang G, Zhang S, Yu H, Wu Y, Jiang T, Wang F*, Wang Y*, Zhang L*. 2019. Immunoactive Astragalus Polysaccharide Functionalized Gold Nanocomposites Promote Dendritic Cell Stimulation and Anti-tumor Effect with Elicited Memory T-cell Responses. Nanomedicine 14(10):1291-1306.

35.Zhang S, Pang G, Chen C, Qin J, Yu H, Liu Y, Zhang X, Song G, Zhao J, Wang F*, Wang Y*, Zhang L*. 2019. Effective Cancer Immunotherapy by Ganoderma Lucidum Polysaccharide-Gold Nanocomposites through Dendritic Cell Activation and Memory T cell Response. Carbohydrate Polymer 205:192-202.

36.Yan R, Chen J, Wang J, Rao J, Du X, Liu Y, Zhang L, Qiu L, Liu B, Zhao YD, Jiang P, Chen C, Li YQ. 2018. A NanoFlare-Based Strategy for In Situ Tumor Margin Demarcation and Neoadjuvant Gene/Photothermal Therapy. Small. e1802745.

37.Zhang L*, Monteiro-Riviere NA Toxicity Assessment of Six Titanium Dioxide Nanoparticles in Human Epidermal Keratinocytes. 2018. Cutaneous and Ocular Toxicology. 2018:1-29.

38.Song ZT, Zhang L, Fan LQ, Kong JW, Mao JH, Zhao J, Wang FJ. 2018. Enhanced anticancer effect of MAP30-S3 by cyclosproin A through endosomal escape. Anti-cancer Drugs 29(8):736-747.

39.Pang G, Wang F*, Zhang L*. 2018. Direct Killing or Immunoregulatory Effects of Natural Polysaccharides in Cancer Treatment. Carbohydrate Polymer 195: 243–256.

40.Liu Y, Yu H, Zhang X, Wang Y, Zhao J, Shi H, Li R, Wang Y*, Zhang L*. 2018. The Protective Role of Autophagy in Nephrotoxicity Induced by Bismuth Nanoparticles Through AMPK/mTOR Pathway. Nanotoxicology 6:1-16.

41.Zhang X, Yang L, Liu Y, Song Z, Zhao J, Chen D, Yu Huan, Li R, Wang Y, Yang K, Chen Y, Xia M, Zhang L*. 2018. Detection of Nanocarrier Potentiation on Drug Induced Phospholipidosis in Cultured Cells and Primary Hepatocyte Spheroids by High Content Imaging and Analysis. Toxicology and Applied Pharmacology 348: 54–66.

42.Chen D, Yang L, Chen X, Zhang X, Liu Y, Guo Z*, Zhang L*. 2018. Automated contour analysis of multi-cellular spheroids spreading through high content imaging. Physical Biology 24: 15:026006

43.Liu Y, Shen C, Zhang X, Yu H, Wang F, Wang Y*, Zhang L*. 2018. Exposure and Nephrotoxicity Concern of Bismuth with the Occurrence of Autophagy. Toxicology and Industrial Health 34:188–199

44.Yue C, Ji C, Zhang H, Zhang L, Tong J, Jiang Y, Chen T*. 2017. Protective effects of folic acid on PM2.5-induced cardiac developmental toxicity in zebrafish embryos by targeting AhR and Wnt/β-catenin signal pathways. Environmental Toxicology. 32:2316-2322.

45.Pei W, Tao L, Zhang L, Zhang S, Cao J, Jiao Y, Tong J* and Nie J*. 2017. Circular RNA profiles in mouse lung tissue induced by radon. Environmental Health and Preventive Medicine 22:36.

46.Li J, He X, Zou Y, Chen D, Yang L, Rao J, Chen H, Chan M CW, Guo Z*, Zhang L*, Chen C. 2017. Mitochondria-Targeted Platinum(II) Complex: Dual Inhibitory Activities on Tumor Cell Proliferation and Migration/Invasion via Intracellular Trafficking of β-catenin. Metallomics 9:726-733.

47.Liu Y, Zhuang J, Zhang X, Le C, Zhu N, Yang L, Wang Y, Chen T, Wang Y*, Zhang L* 2017. Autophagy Associated Cytotoxicity and Cellular Uptake Mechanisms of Bismuth Nanoparticles in Human Kidney Cells. Toxicology Letters 275: 39-48.

48.Chen D, Monteiro-Riviere NA, Zhang L*. 2017. Intracellular imaging of quantum dots, gold, and iron oxide nanoparticles with associated endocytic pathways. WIREs Nanomedicine and Nanobiotechnology 9(2).

49.Yang L, Zhong X, Li Q, Zhang X, Wang Y, Yang K, Zhang L*. 2017. From the Cover: Potentiation of Drug-Induced Phospholipidosis In Vitro through PEGlyated Graphene Oxide as the Nanocarrier. Toxicological Sciences 156:39–53.

50.Wang Y, Liu Y, Wu Y, Shen J, Lv L, Li L, Yang L, Zeng J, Wang Y,Zhang L*, Li Z*, Gao M*, Chai Z. 2016. BSA-Mediated Synthesis of Bismuth Sulfide Nanotheranostic Agents for Tumor Multimodal Imaging and Thermoradiotherapy. Advanced Functional Materials 26: 5335–5344.

51.Zhu N, Lv X, Wang Y, Li J, Liu Y, Lu W, Yang L, Zhao J, Wang F, Zhang L*. 2016. Comparison of immunoregulatory effects of polysaccharides from three natural herbs and cellular uptake in dendritic cells. International Journal of Biological Macromolecules 93:940–951.

52.Wang Y*, Zhu L, Wang Y, Li L, Lu Y, Shen L*, Zhang L*. 2016. Ultrasensitive GSH-Responsive Ditelluride-Containing Poly(ether-urethane) Nanoparticles for Controlled Drug Release. ACS Applied Materials & Interfaces 8: 35106–35113

53.Lv X, Chen D, Yang L, Zhu N, Li J, Zhao J, Hu Z, Wang F*,Zhang L*. 2016. Comparative Studies on the Immunoregulatory Effects of Three Polysaccharides Using High Content Imaging System. International Journal of Biological Macromolecules 86:28–42.

54.Xin L, Wang J, Zhang L, Che B, Dong G, Fan G, Cheng K. 2016. Development of HSPA1A promoter-driven luciferase reporter gene assays in human cells for assessing the oxidative damage induced by silver nanoparticles. Toxicology and Applied Pharmacology 304:9–17.

55.Zhang L, Koci J, Brett J, Riviere JE, Monteiro-Riviere NA. 2015. Safety Assessment of Potential Food Ingredients in Canine Hepatocytes. Food and Chemical Toxicology 78:105–15.

56.Rouse RL, Zhang L, Shea K, Zhou H, Xu L, Sharron S, Rosenzweig B, Zhang J. 2014. Extended Exenatide Administration Enhances Lipid Metabolism and Exacerbates Pancreatic Injury in Mice on a High Fat, High Carbohydrate Diet. PLOS ONE. 9(10):e109477

57.Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, González C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL. 2014. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicologic Pathology 42(4):709–24.

58.Zhang L, Shea KI, Xu L, Stewart S, Zhang J, Rouse RL. 2014. Autophagy in pancreatic acinar cells in caerulein treated mice: Immunolocalization of related proteins and their potential as markers of pancreatitis. Toxicologic Pathology 42, 435–457.

59.Zhang L, Monteiro-Riviere NA. 2013. Use of confocal microscopy for nanoparticle drug delivery through skin. Journal of Biomedical Optics. 18(6):061214

60.Zhang L, McMahon Tobin GA, Rouse RL. 2012. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line. Toxicology and Applied Pharmacology 264: 274–283.

61.Zhang L, Bäumer W, Monteiro-Riviere NA. 2011. Cellular uptake mechanisms and toxicity of quantum dots in dendritic cells. Nanomedicine. 6: 777–791.

62.Zhang L, Monteiro-Riviere NA. 2010. Lectins modulate multi-walled carbon nanotubes cellular uptake in human epidermal keratinocytes. Toxicology In Vitro 24: 546–555.

63.Zhang L, Yang J, Barron AR, Monteiro-Riviere NA. 2009.Endocytic mechanisms and toxicity of a functionalized fullerene in human cells. Toxicology Letters 191: 149–157.

64.Zhang L, Monteiro-Riviere NA. 2009. Mechanisms of quantum dot nanoparticle cellular uptake. Toxicological Sciences. 110: 138–155.

65.Chen T, Li M, Ding Y, Zhang L, Xi Y, Pan WJ, Tao DL, Wang JY, Li L. 2009. Identification of zinc-finger bed domain containing 3 (ZBED3) as a novel axin-interacting protein that activates WNT/beta –catenin signalling. The Journal of Biological Chemistry 284: 6683–6689.

66.Monteiro-Riviere NA, Inman Al, Zhang L. 2009. Limitations and relative utility of screening assays to assess nanoparticle toxicity in a human cell line. Toxicology and Applied Pharmacology 234: 222–235.

67.Zhang L, Monteiro-Riviere NA. 2008. Assessment of quantum dot penetration into intact, tape-stripped, abraded and flexed rat skin. Skin Pharmacology and Physiology 21:166 –180.

68.Zhang L, Yu WW, Colvin VL, Monteiro-Riviere NA. 2008. Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes. Toxicology and Applied Pharmacology 228:200–211.

69.Zhang L, Zeng L, Barron AR, Monteiro-Riviere NA. 2007. Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. International Journal of Toxicology 26:103–113.

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73.汪祺,王曼虹,王亚丹,张乐帅,马双成*,文海若*.不同企业雷公藤多苷片及其主要单体成分药效作用评价[J/OL].中国现代中药:2021, 23(8)

74.汪祺,张茜蕙,文海若,郭浩翔,张乐帅*,马双成*. 基于肝微组织考察何首乌主要单体潜在肝毒性[J].中国中药杂志,2020,45(12):2954-2959.

75.李菁玲,曹建平,陈春英,郭正清,张乐帅*.新型铂配合物Mor-platin导致细胞凋亡及抑制细胞迁移[J].科学通报,2017,62(04):270-278.

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