个人资料
- 直属机构:苏州医学院基础医学院
- 联系电话:
- 性别:男
- 电子邮箱:chaohong@suda.edu.cn
- 专业技术职务:
- 办公地址:403-3416
- 毕业院校:
- 通讯地址:
- 学位:
- 邮编:
- 学历:
- 传真:
教育经历
- 2000.9-2005.6,临床医学,郑州大学,本科
- 2005.9-2010.6,免疫学,北京大学医学部,博士
工作经历
- 2010.8-2013.6,苏州大学生物医学研究院,讲师
- 2013.7-2024.9,苏州大学生物医学研究院,副教授
- 2024.10-至今,苏州大学基础医学院,副教授
个人简历
洪超,免疫学博士,苏州大学基础医学院副教授。担任中国免疫学会临床免疫分会委员会委员,自身免疫分会委员会委员。十余年来主要从事自身免疫病,干细胞治疗等领域的科学研究,致力于促进基础研究成果向临床进行科研转化。
基金项目:
1.单倍体相合造血干细胞移植后免疫耐受及重建的机制研究。(科技部国家重点研发计划项目干细胞及转化研究专项,2017-2021,参与)
2.重组钙网蛋白激活调节性B细胞及机制研究。(国家自然科学基金青年项目,2012-2014,主持)
3.重组钙网蛋白抑制小鼠实验型自身反应性脑脊髓炎的研究。(江苏省属高校自然科学研究面上项目,2011-2013,主持)
4.类风湿性关节炎患者血液及关节液中可溶性钙网蛋白的纯化及免疫生物学活性研究。(国家自然科学基金青年项目,2013-2015,参与)
5.MMP3入核激活NFkB:MMP3抗登革病毒感染的新机制(国家自然科学基金青年项目,2013-2015,参与)
代表性论文(*第一作者,#通讯作者):
1. Hong C#, Lu H, Huang X, Chen M, Jin R, Dai X, Gong F, Dong H, Wang H, Gao X#. Neutrophils as regulators of macrophage-induced inflammation in a setting of allogeneic bone marrow transplantation. Stem Cell Reports. 2022, 17: 1561-1575.
2. Hong C#, Lu H, Jin R, Huang X, Chen M, Dai X, Gong F, Dong H, Wang H, Gao X#. Cytokine cocktail promotes alveolar macrophage reconstitution and functional maturation in a murine model of haploidentical bone marrow transplantation. Front Immunol.2021, 12:719727.
3. Pan L*, Hong C*, Chan LN*, Xiao G, Malvi P, Robinson ME, Geng H, Reddy ST, Lee J, Khairnar V, Cosgun KN, Xu L, Kume K, Sadras T, Wang S, Wajapeyee N, Muschen M. PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis. Proc Natl Acad Sci U S A. 2021,118:e2016553118.
4. Hong C#, Jin R, Dai X, Gao X#. Functional Contributions of Antigen Presenting Cells in Chronic Graft-Versus-Host Disease. Front Immunol.2021, 12:614183.
5. Dong H, Yang Y, Gao C, Sun H, Wang H, Hong C, Wang J, Gong F, Gao X.Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype.J Immunother Cancer. 2020, 8: e000339.
6. Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, Hong C, Polonen P, Nix MA, Chen Z, Chen CW, Chen J, Vogt A, Heinaniemi M, Lohi O, Wiita AP, Izraeli S, Geng H, Weinstock DM, Muschen M.Signalling input from divergent pathways subverts B cell transformation. Nature. 2020, 583:845-851.
7. Gong FY, Gong Z, Duo CC, Wang J, Hong C, Gao X.Aberrant Glycosylation Augments the Immuno-Stimulatory Activities of Soluble Calreticulin. Molecules. 2018, 23:E523.
8. Zhang T, Xia Y, Zhang L, Bao W, Hong C#, Gao X#.CD1d(hi)CD5(+) B cells differentiate into antibody-secreting cells under the stimulation with calreticulin fragment.Protein Cell. 2013, 4:872-881.
9. Hong C, Zhang T, Gao XM.Recombinant murine calreticulin fragment 39-272 expands CD1d(hi)CD5+ IL-10-secreting B cells that modulate experimental autoimmune encephalomyelitis in C57BL/6 mice. Mol Immunol. 2013, 55:237-246.
10. Qiu X*, Hong C*, Zhong Z, Li Y, Zhang T, Bao W, Xiong S, Gao X. Modulation of cellular immunity by antibodies against calreticulin. Eur J Immunol.2012, 42:2419-2430.
11. Qiu X, Hong C, Li Y, Bao W, Gao X.Calreticulin as a hydrophilic chimeric molecular adjuvant enhances IgG responses to the spike protein of severe acute respiratory syndrome coronavirus. Microbiol Immunol. 2012, 56:554-561.
12. Cui YR, Hong C, Zhou YL, Li Y, Gao X, Zhang X.Synthesis of orientedly bioconjugated core/shell Fe3O4@Au magnetic nanoparticles for cell separation. Talanta. 2011, 85:1246-1252.
13. Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, Liu X, Sun L, Lv P, Gao X.Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol. 2010, 185:4561-4569.