姓名：郝宗兵

郝宗兵，副教授，硕士生导师，苏州大学优秀青年学者。2019年于苏州大学获得药理学博士学位，2020-2023在苏州大学神经科学研究所进行博士后研究。2023年3月入职苏州大学药学院，主要从事肌萎缩侧索硬化症的致病分子机制研究，作为通讯作者/第一作者在Nature Communications（2019，2026）、Human Molecular Genetics、Neuroscience Bulletin等国际知名期刊发表SCI论文。研究获得国家自然科学基金青年项目、苏州市科技局应用基础研究青年项目、苏州医学院医学交叉种子基金等项目资助。

代表性论文：

1. Wang, Y.#, Hu, W.#, Huang, R., Wu, F., Su, H., Zang, J., Huang, X., Liu, Y., Ren, H., Li, J.*, Zhang, M.*, Zhang, Y.*, Wang, G.*, and Hao, Z.* (2026). Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction. Nat Commun 17, 8596. 10.1038/s41467-026-75500-z.

2. Wang, Y.#, Liu, L.#, Chen, H., Yang, Y., Mu, C., Ren, H., Liu, Y., Yu, L., Fang, Q., Wang, G.*, and Hao, Z.* (2023). Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis. Hum Mol Genet 33, 64-77. 10.1093/hmg/ddad163.

3. Hao, Z., Wang, R., Ren, H., and Wang, G. (2020). Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Neurosci Bull 36, 1057-1070. 10.1007/s12264-020-00567-7.

4. Wang, R.#, Xu, X.#, Hao, Z.#, Zhang, S., Wu, D., Sun, H., Mu, C., Ren, H., and Wang, G. (2019). Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis. Neurosci Bull 35, 889-900. 10.1007/s12264-019-00395-4.

5. Hao, Z., Liu, L., Tao, Z., Wang, R., Ren, H., Sun, H., Lin, Z., Zhang, Z., Mu, C., Zhou, J., and Wang, G. (2019). Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR. Nat Commun 10, 2906. 10.1038/s41467-019-10956-w.