个人简介
2004年获苏州大学药理学硕士学位，2007年获中国科学院大连化学物理所分析化学博士学位。1999年至今工作于苏州大学苏州医学院药学院药理学系。研究方向为呼吸药理学，在国家自然科学基金资助下较为系统阐述了黄芩素、海藻糖、中药野马追黄酮与倍半萜内酯等的抗肺纤维化活性及其新的分子机制，同时发展并应用蛋白质组学技术开展了肺纤维化药物靶点探索工作。以通讯作者（含共同通讯）在药学学报、中国药理学通报、中国药理学报（Acta Pharmacologica Sinica）、Biochemical Pharmacology、Toxicology and Applied Pharmacology、Toxicology Letters、Pulmonary Pharmacology & Therapeutics等杂志发表学术论文20余篇。获呼吸系统疾病先导活性物质授权专利1项。作为主要参与人（5/16）获教育部科学技术进步奖二等奖1项。
教育经历
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2004-2007,分析化学,中国科学院大连化学物理研究所,博士
研究领域
呼吸药理学 1. 特发性肺纤维化药物发现及其机制研究 2. 呼吸系统药物的不良反应及其机制研究
论文
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1、Mitomycin induced the senescence of alveolar epithelial cells by targeting peroxiredoxin I,Biochemical Pharmacology,2025,蒋小岗（共同通讯）,苏州大学,236/116890
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2、RNA-binding motif protein RBM39 enhances the proliferation of gastric cancer cells by facilitating an oncogenic splicing switch in MRPL33,Acta Pharmacologica Sinica,2025,蒋小岗（共同通讯）,苏州大学,46/1068–1081
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3、海藻糖药理作用研究进展,天然产物研究与开发,2024,蒋小岗（通讯作者）,苏州大学,36/1813-1819
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4、Total sesquiterpenoids from Eupatorium lindleyanum DC. attenuate bleomycin-induced lung fibrosis by suppressing myofibroblast transition,Fitoterapia,2023,蒋小岗（共同通讯）,苏州大学,169/105567
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5、Collagen targeting liposomes, a promising strategy for idiopathic pulmonary fibrosis,Journal of Controlled Release,2023,蒋小岗（通讯作者）,苏州大学,361/896-897.
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6、Comment on “Reactive oxygen species-responsive polypeptide drug delivery system targeted activated hepatic stellate cells to ameliorate liver fibrosis”,ACS nano,2023,蒋小岗（通讯作者）,苏州大学,17/4094-4095
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7、Da-Yuan-Yin decoction polyphenol fraction attenuates acute lung injury induced by lipopolysaccharide,Pharmaceutical Biology,2023,蒋小岗（共同通讯）,苏州大学,61/228–240
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8、肺肌成纤维细胞转化的研究新进展,中国药理学通报,2023,蒋小岗（通讯作者）,苏州大学,39/1-4
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9、Eupafolin suppresses TGF-β1-induced human lung fibroblasts differentiation by downregulating β-catenin/plasminogen activator inhibitor-1 signaling,Pharmacological Research-Modern Chinese Medicine,2022,蒋小岗（共同通讯）,苏州大学,2/100056
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10、Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays,Fitoterapia,2022,蒋小岗（共同通讯）,苏州大学,156/105100
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11、Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling,Toxicology Letters,2021,蒋小岗（通讯作者）,苏州大学,352/61-69
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12、蓝萼甲素下调GSK3β/β-catenin信号通路抑制TGF-β1诱导的肺成纤维细胞转化,药学学报,2021,蒋小岗（通讯作者）,苏州大学,56/2950-2956
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13、MYH9 inhibition suppresses TGF-β1-stimulated lung fibroblast-to-myofibroblast differentiation,Frontiers in Pharmacology,2021,蒋小岗（通讯作者）,苏州大学,11/573524
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14、Baicalein alleviated TGF β1-induced type I collagen production in lung fibroblasts via downregulation of connective tissue growth factor,Biomedicine & Pharmacotherapy,2020,蒋小岗（通讯作者）,苏州大学,131/110744
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15、SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose,Toxicology and Applied Pharmacology,2020,蒋小岗（通讯作者）,苏州大学,391/114916
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16、Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21,Toxicology and Applied Pharmacology,2018,蒋小岗（通讯作者）,苏州大学,358/35-42
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17、Comparative proteome profiling of bleomycin-induced lung toxicity in rats by 2D-nano-LC-MS/MS and spectral counting,Biomedical Chromatography,2017,蒋小岗（通讯作者）,苏州大学,31/e3857
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18、Automated platform of μLC-MS/MS using SAX trap column for highly efficient phosphopeptide analysis,Analytical and Bioanalytical Chemistry,2017,蒋小岗（通讯作者）,苏州大学,409/2489-2493
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19、Edman降解中异硫氰酸苯酯新修饰位点的发现和验证,色谱,2016,蒋小岗（通讯作者）,苏州大学,34/752-756
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20、Baicalein attenuates bleomycin-induced pulmonary fibrosis in rats through inhibition of miR-21,Pulmonary Pharmacology & Therapeutics,2013,蒋小岗（通讯作者）,苏州大学,26/649-654
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21、Combination of FASP and fully automated 2D-LC-MS/MS allows in-depth proteomic characterization of mouse zymogen granules,Biomedical Chromatography,2013,蒋小岗（通讯作者）,苏州大学,27/407-408
科研成果
软件著作 专利
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1、野马追倍半萜内酯在制备预防或治疗肺纤维化药物中的应用,ZL 2022 1 0081704.0,苏州大学,蒋小岗,发明专利
荣誉及奖励
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1、教育部科学技术进步二等奖,苏州大学,蒋小岗（5/16）,2021
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