吴嘉炜

发布时间:2019-02-27浏览次数:347

1. Ghai R, Du X, Wang H, Dong J, Ferguson C, Brown AJ, Parton RG, Wu JW*,Yang H*. (2017) ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate(PtdIns(4,5)P2) and regulate its level at the plasma membrane. Nat Commun. 8(1):757.

2. Li SJ, Wang J, Ma L, Lu C, Wang J, Wu JW*, Wang ZX*. (2016) Cooperativeautoinhibition and multi-level activation mechanisms of calcineurin. Cell Res. 26(3):336-49.

3. Wu JX, Cheng YS, Wang J, Chen L, Ding M, Wu JW*(2015) Structural insightinto the mechanism of synergistic autoinhibition of SAD kinases. Nat Commun. 6:8953

4. Chai N, Li WX, Wang J,Wang ZX, Yang SM, Wu JW*. (2015) Structural basis for the Smad5 MH1domain to recognize different DNA sequences. Nucleic Acids Res. 43(18):9051-64.

5. Xin FJ, Wang J, Zhao RQ, Wang ZX, Wu JW*.(2013) Coordinated regulation of AMPK activity by multiple elements in theα-subunit. Cell Res. 23(10):1237-1240.

6. Chen L, Xin FJ, Wang J, Hu J, Zhang YY, Wan S,Cao LS, Lu C, Li P, Yan SF,Neumann D, Schlattner U, Xia B, Wang ZX, Wu JW*. (2013) ConservedRegulatory Elements in AMPK. Nature.498(7453):E8–E10.

7. Chen L, Wang J, Zhang YY, YanSF, Neumann D, Schlattner U, Wang ZX, Wu JW*. (2012)AMP-activated protein kinase undergoes nucleotide-dependent conformationalchanges. Nat Struct Mol Biol. 19(7):716-718.

8. Gao X, Wang J, Yu DQ, Bian F, Xie BB, Chen XL, Zhou BC, Lai LH, Wang ZX, Wu JW*, Zhang YZ*. (2010) Structuralbasis for the autoprocessing of zinc metalloproteases in the thermolysinfamily. Proc Natl Acad Sci U S A. 107(41):17569-74.

9. Zhao PL, Wang L, Zhu XL, Huang X, Zhan CG*, WuJW*, Yang GF*. (2010) Subnanomolar Inhibitor of Cytochrome bc(1) ComplexDesigned by Optimizing Interaction with Conformationally Flexible Residues. J AmChem Soc. 132(1):185-94.

10. Chen L, Jiao ZH, Zheng LS, Zhang YY, Xie ST, Wang ZX, Wu JW*. (2009) Structural insight into the autoinhibition mechanismof AMP-activated protein kinase. Nature. 459(7250):1146-9.