严文颖

发布时间:2023-10-01浏览次数:1230


2023年

MiR-200/183 family-mediated module biomarker for gastric cancer progression: an AI-assisted bioinformatics method with experimental functional survey

Wenying Yan; Yuqi Chen; Guang Hu; Tongguo Shi; Xingyi Liu; Juntao Li; Linqing Sun; Fuliang Qian; Weichang Chen.

Journal of Translational Medicine, 2023, 21(1) (SCI大类二区,第一作者)


Integrated multi-dimensional analysis highlights DHCR7 mutations involving in cholesterol biosynthesis and contributing therapy of gastric cancer

Yuqi Chen; Wenying Yan; Kexi Yang; Yiting Qian; Yanjun Chen; Ruoqin Wang; Jinghan Zhu; Yuxin He; Hongya Wu; Guangbo Zhang; Tongguo Shi; Weichang Chen

Journal of Experimental & Clinical Cancer Research, 2023, 42(1) (SCI大类一区,并列第一作者)


Identifying lymph node metastasis-related factors in breast cancer using differential modular and mutational structural analysis.

Xingyi Liu; Bin Yang; Xinpeng Huang; Wenying Yan; Yujuan Zhang; Guang Hu.

Interdisciplinary Sciences: Computational Life Sciences, 2023, Online ahead of prin(SCI大类三区,并列通讯作者)


A comprehensive review on knowledge graphs for complex diseases

Yang, Yang; Lu, Yuwei; Yan, Wenying

Briefings in Bioinformatics, 2023, 24(1) (SCI大类二区,通讯作者)


A protein co-conservation network model characterizes mutation effects on SARS-CoV-2 spike protein.

Lianjie Zeng; Yitan Lu; Wenying Yan; Yang Yang

International Journal of Molecular Sciences, 2023, 24(4): 3255 (SCI大类二区,并列通讯作者)


DeepTP: A deep learning model for thermophilic protein prediction.

Jianjun Zhao; Wenying Yan; Yang Yang

International Journal of Molecular Sciences, 2023, 24(3): 2217 (SCI大类二区,并列通讯作者)


2022年

Structural Biology Meets Biomolecular Networks: The Post-AlphaFold Era

Wenying Yan; Guang Hu

Current Bioinformatics, 2022, 17(6). (SCI大四区,第一作者)


2021年

Knowledge-Guided “Community Network” Analysis Reveals the Functional Modules and Candidate Targets in Non-Small-Cell Lung Cancer

Fan Wang; Shuqing Han; Ji Yang; Wenying Yan; Guang Hu

Cells, 2021, 10(2): 402. (SCI大类二区,并列通讯作者)


Network-Based Target Prioritization and Drug Candidate Identification for Multiple Sclerosis: From Analyzing “Omics Data” to Druggability Simulations

Ji Yang; Hongchun Li; Fan Wang; Fei Xiao; Wenying Yan; Guang Hu

ACS Chemical Neuroscience, 2021, 12(5): 917-929. (SCI大类二区,并列通讯作者)


Deciphering the in vivo Dynamic Proteomics of Mesenchymal Stem Cells in Critical Limb Ischemia

Yipeng Du; Xiaoting Li; Wenying Yan; Zhaohua Zeng; Dunzheng Han; Hong Ouyang; Xiudi Pan; Bihui Luo; Bohua Zhou; Qiang Fu; Dongfeng Lu; Zheng Huang; Zhiliang Li

Frontiers in Cell and Developmental Biology, 2021, 9 (SCI大类二区,并列第一作者)


2020年

Evaluation of plasma exosomal microRNAs as circulating biomarkers for progression and metastasis of gastric cancer

Yuqi Chen; Huang Feng; Yanlin Wu; Ruoqin Wang; Zhaoji Li; Jiajia Chen; Wenying Yan; Weichang Chen

Clinical and Translational Medicine, 2020, 10(6). (SCI大类一区,并列通讯作者)


Identifying drug targets in pancreatic ductal adenocarcinoma through machine learning, analyzing biomolecular networks, and structural modeling

Wenying Yan; Xingyi Liu; Yibo Wang; Shuqing Han; Fan Wang; Xin Liu; Fei Xiao; Guang Hu

Frontiers in Pharmacology, 2020, 11: 0-534. (SCI大类二区,第一作者)


ANCA: A web server for amino acid networks construction and analysis

Wenying Yan; Chunjiang Yu; Jiajia Chen; Jianhong Zhou; Bairong Shen

Frontiers in Molecular Biosciences, 2020, 7: 582702. (SCI大类二区,第一作者)


Understanding the cross-talk between host and virus in poultry from the perspectives of microRNA

Xiujun Duan; Lihua Wang; Guobo Sun; Wenying Yan; Yang Yang

Poultry Science, 2020, 99(4): 1838-1846. (SCI大类二区,并列通讯作者)


2018年

Node-Weighted amino acid network strategy for characterization and identification of protein functional residues

Wenying Yan; Guang Hu; Zhongjie Liang; Jianhong Zhou; Yang Yang; Jiajia Chen; Bairong Shen

Journal of Chemical Information and Modeling, 2018, 58(9): 2024-2032. (SCI大类二区,第一作者,JCIM封面论文


Recent Advances on the Network Models in Target-based Drug Discovery

Wenying Yan; Daqing Zhang; Chen Shen; Zhongjie Liang; Guang Hu

Current Topics in Medicinal Chemistry, 2018, 18(13): 1031-1043.(SCI大类四区,第一作者)


2016年

Network analysis of protein structures: the comparison of three topologies

Wenying Yan; Guang Hu; Bairong Shen

Current Bioinformatics, 2016, 11(4): 480-489. (SCI大类三区,第一作者)


Comparison of prognostic microrna biomarkers in blood and tissues for gastric cancer

Wenying Yan; Laijun Qian; Jiajia Chen; Weichang Chen; Bairong Shen

Journal of Cancer, 2016, 7(1): 95-106. (SCI大类三区,第一作者)


2014年

Amino acid contact energy networks impact protein structure and evolution

Wenying Yan; Maomin Sun; Guang Hu; Jianhong Zhou; Wenyu Zhang; Jiajia Chen; Biao Chen; Bairong Shen

Journal of Theoretical Biology, 2014, 355: 95-104. (SCI大类三区,第一作者)


The construction of an amino acid network for understanding protein structure and function

Wenying Yan; Jianhong Zhou; Maomin Sun; Jiajia Chen; Guang Hu; Bairong Shen

Amino Acids, 2014, 46(6): 1419-1439. (SCI大类三区,第一作者)


SVR_CAF: an integrated score function for detecting native protein structures among decoys

Jianhong Zhou; Wenying Yan; Guang Hu; Bairong Shen

Proteins, 2014, 82(4): 556-564. (SCI大类三区,并列第一作者)


Amino acid network for the discrimination of native protein structures from decoys

Jianhong Zhou; Wenying Yan; Guang Hu; Bairong Shen

Current Protein and Peptide Science, 2014, 15(6): 522-528. (SCI大类三区,并列第一作者)


专著

沈百荣主编,严文颖、张文宇、钱福良、 林宇鑫副主编,《深度测序数据的生物信息学分析及实例》,2017,科学出版社,ISBN:9787030545800


专利

2、杨洋; 朱冠臣; 丁雪松; 吕强; 严文颖; 朱斐一种基于序列预测蛋白质变性温度的系统及其方法。授权日期:2023-3-31。专利号:ZL201910719819.6

1、严文颖; 沈百荣; 杨洋基于结构网络模型的蛋白质功能位点预测方法。授权日期:2021-3-30。专利号:ZL201810643576.8