发表论文Publications-2025

1. Xingbo Mo, Imre Janszky, Hui Wang, Jette Möller, Yajun Liang, Krisztina D László. Psychiatric disorders and the risk of atrial fibrillation: a Swedish population-based cohort study. Eur J Prev Cardiol (IF = 7.5). 2025 Dec 15:zwaf773. PMID: 41392705. DOI: 10.1093/eurjpc/zwaf773

2. Zhang H, Fan K, Jia S, Gao Q, Zhang Z, Long J, Li D, Mo X*. Deciphering genetic associations with blood pressure in peripheral blood mononuclear cells through single-cell transcriptomic profiling. Hypertens Res (IF = 4.6). 2025 Nov;48(11):2969-2978.

发表论文Publications-2024

1. Zhang H, Zhang Z, Fan K, Chen Y, Xu P, Guo Y, Mo X*. Deciphering cell-specific genetic insights: Unraveling the immunogenetic landscape of systemic lupus erythematosus. Mol Immunol. 2024 Nov;175:165-175.

2. Zhang H, Fan K, Zhang Z, Guo Y, Mo X*. Genome-wide identification of cell type-specific susceptibility genes for Juvenile dermatomyositis through the analysis of N6-methyladenosine-associated SNPs. Autoimmunity. 2024 Dec;57(1):2419117.

3. Zhang H, Fan K, Chen Y, Xu P, Zhang Z, Mo X*, Guo Y*. Genome-Wide Identification of Cell Type-Specific Susceptibility Genes for SLE Through the Analysis of RNA Modification-Associated SNPs. Immunol Invest. 2024 Nov;53(8):1264-1278.

4. Zhang H, Zhang Z, Fan K, Chen H, Guo Y, Mo X*. Decoding the genetic landscape of juvenile dermatomyositis: insights from phosphorylation-associated single nucleotide polymorphisms. Immunogenetics. 2024 Dec;76(5-6):291-304.

5. Zhang H, Chen Y, Xu P, Liu D, Wu N, Wang L, Mo X*. Unveiling blood pressure-associated genes in aortic cells through integrative analysis of GWAS and RNA modification-associated variants. Chronic Dis Transl Med. 2024 Apr 30;10(2):118-129.

6. Gao Q, Jia S, Mo X*, Zhang H*. Association of cardiorenal biomarkers with mortality in metabolic syndrome patients: A prospective cohort study from NHANES. Chronic Dis Transl Med. 2024 Sep 3;10(4):327-339.

发表论文Publications-2023

1. Mo XB, Sun YH, Wu LF, He P, Cao RR, Lu X, Zhang YH, Deng FY, Lei SF*.  A novel long noncoding RNA, lnc-RNU12, influences the T-cell cycle via  c-JUN and CCNL2 in rheumatoid arthritis. Rheumatology (Oxford). 2023 May 2;62(5):1955-1963.

2.Wang M, Wu J, Lei S, Mo X*. Genome-wide identification of RNA modification-related single nucleotide polymorphisms associated with rheumatoid arthritis. BMC Genomics. 2023 Mar 27;24(1):153.

发表论文Publications-2022

1. Han L, Wu J, Wang M, Zhang Z, Hua D, Lei S, Mo X*. RNA Modification-Related Genetic Variants in Genomic Loci Associated with Bone Mineral Density and Fracture. Genes. 2022 Oct 18;13(10):1892.

2. Li R, Zhang H, Tang F, Duan C, Liu D, Wu N, Zhang Y, Wang L, Mo X*. Coronary artery disease risk factors affected by RNA modification-related genetic variants. Front Cardiovasc Med. 2022 Sep 20;9:985121.

3. Wu J, Wang M, Han L, Zhang H, Lei S, Zhang Y, Mo X*. RNA modification-related variants in genomic loci associated with body mass index. Hum Genomics. 2022 Jul 25;16(1):25.

4. Tang F, Duan C, Li R, Zhang H, Mo X*. Identification of RNA modification-associated single-nucleotide polymorphisms in genomic loci for low-density lipoprotein cholesterol concentrations. Pharmacogenomics. 2022 Jul 26; 23(11): 655-665.

5. Zhang H, Wang A, Xu T, Mo X*, Zhang Y*. Promoter DNA methylations in GWAS-identified genes as potential functional elements for blood pressure: an observational and Mendelian randomization study.Front Genet. 2022 Jan 11;12:791146.

6. Zhang H^#, Mo X^#, Wang A, Peng H, Guo D, Zhong C, Zhu Z, Xu T, Zhang Y*. Association of DNA Methylation in Blood Pressure-Related Genes With Ischemic Stroke Risk and Prognosis. Front Cardiovasc Med. 2022 Mar 8;9:796245.

7. Lu X, Liu Z, Cui Q, Liu F, Li J, Niu X, Shen C, Hu D, Huang K, Chen J, Xing X, Zhao Y, Lu F, Liu X, Cao J, Chen S, Ma H, Yu L, Wu X, Wu X, Li Y, Zhang H, Mo X, Zhao L, Huang J, Wang L, Wen W, Shu XO, Takeuchi F, Koh WP, Tai ES, Cheng CY, Wong TY, Chang X, Chan MY, Gao W, Zheng H, Chen K, Chen J, He J, Tang CS, Lam KSL, Tse HF, Cheung CYY, Takahashi A, Kubo M, Kato N, Terao C, Kamatani Y, Sham PC, Heng CK, Hu Z, Chen YE, Wu T, Shen H, Willer CJ, Gu D. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022 May 7;43(18):1702-1711.

8. Wu LF, Zhang Q, Mo XB, Lin J, Wu YL, Lu X, He P, Wu J, Guo YF, Wang MJ, Ren WY, Deng HW, Lei SF, Deng FY. Identification of novel rheumatoid arthritis-associated MiRNA-204-5p from plasma exosomes. Exp Mol Med. 2022 Mar;54(3):334-345.

发表论文Publications-2021

1.Wu LF^#, Mo XB^#, He JH^#, He P, Lu X, Deng HW, Deng FY, Lei SF.Integrative lncRNA-mRNA co-expression network analysis identifies novel lncRNA E2F3-IT1 for rheumatoid arthritis. Clin Transl Med. 2021 Feb;11(2):e325.

2. Mo XB, Zhang YH, Lei SF. Integrative analysis identifies potential causal methylation-mRNA regulation chains for rheumatoid arthritis. Mol Immunol. 2021 Mar;131:89-96.

发表论文Publications-2020

1. Mo XB^#, Dong CY^#, He P, Wu LF, Lu X, Zhang YH, Deng HW, Deng FY, Lei SF. Alteration of circulating microbiome and its associated regulation role in rheumatoid arthritis: Evidence from integration of multiomics data. Clinical and Translational Medicine;2020 Nov;10(7):e229.

2. Mo XB^#, Zhang H^#, Wang AL, Xu T, Zhang YH. Integrative analysis identifies the association between CASZ1 methylation and ischemic stroke. Neurol Genet; 2020Sep 1;6(5):e509.

3. Mo XB, Sun YH, Zhang YH, Lei SF. Integrative analysis highlighted susceptibility genes for rheumatoid arthritis. Int Immunopharmacol; 2020 Sep;86:106716.

4. Zhang H, Mo X^#, Qian Q, Zhou Z, Zhu Z, HuangFu X, Xu T, Wang A, Guo Z, Lei S, Zhang Y. Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population. BMC Genet; 2019 Dec 19;20(1):99.

发表论文Publications-2019

1. Mo X, Guo Y, Qian Q, Fu M, Zhang H*. Phosphorylation related SNPs influence lipid levels and rheumatoid arthritis risk by altering gene expression and plasma protein levels. Rheumatology. 2019 Sep 10. DOI: 10.1093/rheumatology/kez466.

2. Mo X, Guo Y, Qian Q, Fu M, Lei S, Zhang Y, Zhang H*. Mendelian randomization analysis revealed potential causal factors for systemic lupus erythematosus. Immunology. 2019 Oct 31. doi: 10.1111/imm.13144.

3. Mo XB, Lei SF, Qian QY, Guo YF, Zhang YH, Zhang H. Integrative analysis revealed potential causal genetic and epigenetic factors for multiple sclerosis. J Neurol. 2019 Jul 18. doi: 10.1007/s00415-019-09476-w.

4. Mo X, Lei SF, Zhang Y, Zhang H. Examination of the associations between m6A-associated single nucleotide polymorphisms and blood pressure. Hypertension Research. 2019 Jun 7.DOI : 10.1038/s41440-019-0277-8

5. Zhang H^#, Mo X^#, Zhou Z, Zhu Z, HuangFu X, Xu T, Wang A, Guo Z, Zhang Y. Associations among NPPA gene polymorphisms, serum ANP levels and hypertension in the Chinese Han population. Journal of Human Hypertension. 2019 Jul 24. doi: 10.1038/s41371-019-0219-6.

6. Mo X, Lei SF, Zhang Y, Zhang H. Integrative Analysis Identified IRF6 and NDST1 as Potential Causal Genes for Ischemic Stroke. Frontiers in Neurology. May 2019, 10: 517.

7. Zhang H, Mo X, Zhou Z, Zhu Z, HuangFu X, Guo Z, Zhang Y. Detection of Putative Functional Single Nucleotide Polymorphisms in Blood Pressure Loci and Validation of Association Between Single Nucleotide Polymorphism in WBP1L and Hypertension in the Chinese Han Population. J Cardiovasc Pharmacol. 2019 Jan;73(1):48-55.

8. Mo X, Zhang H, Zhou Z, Zhu Z, HuangFu X, Xu T, Wang A, Guo Z, Zhang Y. SNPs rs10224002 in PRKAG2 may disturb gene expression and consequently affect hypertension. Mol Biol Rep. 2019 Apr;46(2):1617-1624. doi: 10.1007/s11033-019-04610-3.

9. Wang X^#, Mo X^#, Zhang H, Zhang Y, Shen Y. Identification of phosphorylation associated SNPs for blood pressure, coronary artery disease and stroke from genome-wide association studies. Curr Mol Med. 2019 Aug 28. doi: 10.2174/1566524019666190828151540. [Epub ahead of print]

10. Lu YH, Wang BH, Jiang F, Mo XB, Wu LF, He P, Lu X, Deng FY, Lei SF. Multi-omics integrative analysis identified SNP-methylation-mRNA: Interaction in peripheral blood mononuclear cells. J Cell Mol Med. 2019 May 20. doi: 10.1111/jcmm.14315.

11. Wang BH, Lu YH, Xia W, Wu LF, Mo XB, Lu X, He P, Lei SF. Distribution of single nucleotide polymorphism with a loss of heterozygosity status and its relevance on gene expression in Chinese Han. J Biol Regul Homeost Agents. 2019 Jul-Aug;33(4):1119-1124.

发表论文Publications-2018

1. ZhuH, Wu LF, Mo XB, Lu X, Tang H, ZhuXW, Xia W, Guo YF, Wang MJ, Zeng KQ, Wu J, Qiu YH, Lin X, Zhang YH, Liu YZ, YiNJ, Deng FY, Lei SF. Rheumatoid arthritis-associated DNA methylation sites inperipheral blood mononuclear cells. Ann Rheum Dis. 2019 Jan;78(1):36-42. Epub 2018Oct 8.

2. Mo XB, Wu LF, Lu X, Zhu XW, Xia W, WangL, He P, Bing PF, Zhang YH, Deng FY, Lei SF*. Detection of lncRNA-mRNAinteraction modules by integrating eQTL with weighted gene co-expressionnetwork analysis. Funct Integr Genomics. 2018 Oct 2. 2019 Mar;19(2):217-225.doi:10.1007/s10142-018-0638-4.

3. Mo X, Lei S, Zhang Y, Zhang H*. Genome-wideenrichment of m6A-associated single-nucleotide polymorphisms in the lipid loci.Pharmacogenomics J. 2018 Sep 27. 2019 Aug;19(4):347-357.doi: 10.1038/s41397-018-0055-z.

4. Mo XB, Wu LF, Cai XM, Tang ZX, Lu X,Zhang YH, Deng FY, Lei SF. Integrative analysis identified mediation effects oflncRNAs on the correlations between methylation and mRNA. Int J Biochem CellBiol. 2018 Nov;104:66-72. doi: 10.1016/j.biocel.2018.09.005.

5. Mo XB, Lei SF, Zhang YH, Zhang H. Detectionof m6A-associated SNPs as potential functional variants for coronary arterydisease. Epigenomics. 2018 Oct;10(10):1279-1287. doi: 10.2217/epi-2018-0007.

6. Mo XB, Zhang YH, Lei SF. Genome-WideIdentification of N6-Methyladenosine (m6A) SNPs Associated With RheumatoidArthritis. Front Genet. 2018 Aug 3;9:299.

7. Mo XB, Zhang YH, Lei SF. Genome-wideidentification of m6A-associated SNPs as potential functionalvariants for bone mineral density. Osteoporos Int. 2018 Sep;29(9):2029-2039. doi:10.1007/s00198-018-4573-y.

8. Mo X, Zhang H, Lei S, Xu T, Wang A, GuoZ, Zhang Y. Putative functional SNPs in SLC22A3 and H3F3B might influence thedevelopment of CAD by regulating the lipid levels. Thromb Res. 2018 Jun2;168:37-39.

9.WangWY, Ge B, Shi J, Zhou X, Wu LF, Tang CH, Zhu DC, Zhu H, Mo XB, Zhang YH, Deng FY, Lei SF. Plasma gelsolin is associatedwith hip BMD in Chinese postmenopausal women. PLoS One. 2018 May22;13(5):e0197732

10. WuLF, Zhu DC, Tang CH, Ge B, Shi J, Wang BH, Lu YH, He P, Wang WY, Lu SQ, ZhongJ, Zhou X, Zhu K, Ji W, Gao HQ, Gu HB, MoXB, Lu X, Zhang L, Zhang YH, Deng FY, Lei SF. Association of Plasma Irisinwith Bone Mineral Density in a Large Chinese Population Using an ExtremeSampling Design. Calcif Tissue Int. 2018 Sep;103(3):246-251.

11.WuLF, Zhu DC, Wang BH, Lu YH, He P, Zhang YH, Gao HQ, Zhu XW, Xia W, Zhu H, Mo XB, Lu X, Zhang L, Zhang YH, DengFY, Lei SF. Relative abundance of mature myostatin rather thantotal myostatin is negatively associated with bone mineral density in Chinese. JCell Mol Med. 2018 Feb;22(2):1329-1336.

12.LuYH, Wang BH, Xia W, Mo XB, Wu LF,Zhu XW, He P, Xie FF, Lu X, Deng FY, Lei SF. The distribution and functional relevance analysis ofruns of homozygosity (ROHs) in Chinese Han female population. Mol Genet Genomics. 2018 Feb;293(1):197-206.

13.WangL, Zhu J, Deng FY, Wu LF, Mo XB, ZhuXW, Xia W, Xie FF, He P, Bing PF, Qiu YH, Lin X, Lu X, Zhang L, Yi NJ, ZhangYH, Lei SF. Correlation analyses revealed global microRNA-mRNAexpression associations in human peripheral blood mononuclear cells. Mol Genet Genomics. 2018 Feb;293(1):95-105.

14. XieFF, Deng FY, Wu LF, Mo XB, Zhu H, WuJ, Guo YF, Zeng KQ, Wang MJ, Zhu XW, Xia W, Wang L, He P, Bing PF, Lu X, ZhangYH, Lei SF. Multiple correlation analyses revealed complexrelationship between DNA methylation and mRNA expression in human peripheralblood mononuclear cells. Funct Integr Genomics. 2018Jan;18(1):1-10.

15. ZhangH, Mo X, Zhou Z, Zhu Z, Huangfu X,Xu T, Wang A, Guo Z, Zhang Y. Smoking modifies the effect of two independentSNPs rs5063 and rs198358 of NPPA on central obesity in the Chinese Hanpopulation. J Genet. 2018 Sep;97(4):987-994.

16. 莫兴波, 张永红*，基于多组学的心血管疾病危险因素研究. 中华疾病控制杂志，2018,22(9):873-879.

发表论文Publications-2017

1. MoXB, Wu LF, Zhu XW, Xia W, Wang L, He P, Bing PF, Lu X, Zhang YH, Deng FY, LeiSF. Identification and evaluation of lncRNA and mRNA integrative modules inhuman peripheral blood mononuclear cells. Epigenomics. 2017 Jul;9(7):943-954.(IF =4.541,二区)

2.Xia W, Zhu XW, Mo XB, Wu LF, Wu J, Guo YF, Zeng KQ, Wang MJ, Lin X, Qiu YH,Wang L, He P, Xie FF, Bing PF, Lu X, Liu YZ, Yi NJ, Deng FY, Lei SF. Integrativemulti-omics analysis revealed SNP-lncRNA-mRNA (SLM) networks in humanperipheral blood mononuclear cells. Hum Genet. 2017 Apr;136(4):451-462. doi:10.1007/s00439-017-1771-1. Epub 2017 Feb 28. (IF =4.637,二区)

发表论文Publications-2016
1.Zhang H, Mo X*, Xu T, Bu X, Lei S, Zhang Y. Detecting novel genes for low-densitylipoprotein cholesterol in European population using bioinformatics analysis.Personalized Medicine. May 2016 ,Vol. 13, No. 3, 225-231, http://www.futuremedicine.com/doi/abs/10.2217/pme.16.1?journalCode=pme.(doi:10.2217/pme.16.1.)(IF =1.336,四区)
2.Mo X, Zhang H, Xu T, Bu X, Lei S, Zhang Y*. Identification of important genes associatedwith total cholesterol using bioinformatics analysis. Pharmacogenomics.2016 Feb;17(3):219-230. DOI 10.2217/PGS.15.164 (IF =3.218,二区).

3. ZhuH, Xia W, Mo XB, Lin X, Qiu YH, Yi NJ, Zhang YH, Deng FY, Lei SF. Gene-BasedGenome-Wide Association Analysis in European and Asian Populations IdentifiedNovel Genes for Rheumatoid Arthritis. PLoS One. 2016 Nov 29;11(11):e0167212.doi: 10.1371/journal.pone.0167212.

发表论文Publications-2015

发表论文Publications- Before 2014

1. Mo X#, Liu X#, Wang L, Li H, Lu X, Huang J, Chen J, Cao J, Li J, Chen S, Tang Y, Peng X, Gu D*. Lipoproteinlipase gene polymorphism rs1059611 functionally influences serum lipidconcentrations. Atherosclerosis. 2013;229(2):511-516. (被SCI收录) (IF =3.971,二区)

2. Mo X#, Liu X#, Wang L, Lu X, Chen S, Li H, Huang J, Chen J, Cao J, Li J, Tang Y, Gu D*. Association of lipoproteinlipase polymorphism rs2197089 with serum lipid concentrations and LPL geneexpression. J Hum Genet. 2013;58(3):160-164. (被SCI收录) (IF =2.526,三区)

3. Mo X, Hao Y, Yang X, Chen S, Lu X, GuD*. Association between polymorphisms in the coagulation factor VII gene andcoronary heart disease risk in different ethnicities: a meta-analysis. BMC Medical Genetics. 2011; 12:107. (被SCI收录) (IF =2.45,三区)

4. 莫兴波，顾东风*. 基因型填补的原理与方法及其在遗传流行病学研究中的应用.中华流行病学杂志. 2010; 31(6):702-706.

5. Zhang H, Mo X, Hao Y, Huang J, Lu X, Cao J, Gu D*. Association between adiponectin and incident risk of coronary heartdisease: a meta-analysis. AM J MED SCI.2013; 345(6):455-461. (被SCI收录) (IF =1.515,四区)

6. Zhang H, Mo X, Hao Y, Gu D*. Associationbetween polymorphisms in the adiponectin gene and cardiovascular disease: ameta-analysis. BMC Med Genet. 2012;13:40. (被SCI收录) (IF =2.45,三区)

7. Yang Y, Mo X, Chen S, Lu X, Gu D*.Association of peroxisome proliferator-activated receptor gamma coactivator 1alpha gene polymorphisms and type 2 diabetes mellitus: a meta-analysis. Diabetes Metab Res Rev. 2011;27(2):177-184. (被SCI收录) (IF =3.593,三区)

8. 张欢，莫兴波，郝永臣，陈恕凤，鲁向锋*. 脂联素基因单核苷酸多态性与脑卒中和高血压相关性的荟萃分析. 中国分子心脏病学杂志. 2012; 12(3):136-139.

9. Wang Q, Hao Y, Mo X, Wang L, Lu X, Huang J, Cao J, Li H, Gu D*. PLA2G7gene polymorphisms and coronary heart disease risk: A meta-analysis.ThrombRes. 2010;126(6):498-503. (被SCI收录) (IF =2.427,三区)

10. Yang Y, Li JX, Chen JC, Cao J, Lu XF, Chen SF, Wu XG, Duan XF, Mo XB, Gu DF*. Effect of elevated total cholesterol level andhypertension on the risk of fatal cardiovascular disease: a cohort study ofChinese steelworkers. Chin Med J (Engl). 2011 Nov;124(22):3702-6. (被SCI收录) (IF =1.016,四区)

11. Liang X, Wang Q, Yang X, Cao J, Chen J, Mo X, Huang J, Wang L, Gu D*. Effect of mobile phoneintervention for diabetes on glycaemic control: a meta-analysis. DiabetMed. 2011 Apr;28(4):455-63. (被SCI收录) (IF =3.064,三区)

12. Lu X, Wang L, Chen S, He L, Yang X, Shi Y, Cheng J, Zhang L, Gu CC,Huang J, Wu T, Ma Y, Li J, Cao J, Chen J, Ge D, Fan Z, Li Y, Zhao L, Li H, ZhouX, Chen L, Liu D, Chen J, Duan X, Hao Y, Wang L, Lu F, Liu Z, Yao C, Shen C, PuX, Yu L, Fang X, Xu L, Mu J, Wu X, Zheng R, Wu N, Zhao Q, Li Y, Liu X, Wang M,Yu D, Hu D, Ji X, Guo D, Sun D, Wang Q, Yang Y, Liu F, Mao Q, Liang X, Ji J,Chen P, Mo X, Li D, Chai G, Tang Y,Li X, Du Z, Liu X, Dou C, Yang Z, Meng Q, Wang D, Wang R, Yang J, Schunkert H,Samani NJ, Kathiresan S, Reilly MP, Erdmann J; Coronary ARtery DIseaseGenome-Wide Replication And Meta-Analysis (CARDIoGRAM) Consortium, Peng X, WuX, Liu D, Yang Y, Chen R, Qiang B, Gu D*. Genome-wideassociation study in Han Chinese identifies four new susceptibility loci forcoronary artery disease. Nat Genet. 2012 Jul 1;44(8):890-4. (被SCI收录) (IF =29.648,一区)

会议（conference）- Before 2014:

1. 莫兴波，刘雪会，王来元，李宏帆，陈恕凤，顾东风. 脂蛋白脂酶基因(LPL)3′非翻译区microRNA结合位点多态性与血脂水平及冠心病风险的关联分析。中国循环杂志。2012年8月第27券增刊，第103页。

2. 莫兴波，刘雪会，王来元，陈恕凤，鲁向锋，李宏帆，顾东风. 脂蛋白脂酶基因(LPL)单核苷酸多态性与血脂水平关联分析。中国循环杂志。2012年8月第27券增刊，第105页。

3. 莫兴波，郝永臣，陈京萍，顾东风. 凝血因子Ⅶ基因多态性与冠心病风险的meta分析。中国循环杂志。2010年8月第25券增刊，第6页。

4. Mo XB, Hao YC, Chen JP, GuDF. Polymorphisms in the Coagulation Factor VII Gene and the Risk of CoronaryHeart Disease: A Meta-Analysis of 32 Case-Control Studies. Cardiology. 2010, 117(suppl 1): 6. (被SCI收录)

#并列第一作者；*通讯作者。