朱珂，特聘教授，博士生导师，江苏省特聘教授，国家自然科学基金优秀青年基金（海外）获得者。2013年于南开大学/美国Rush大学医学中心联合培养获博士学位。2013年至2023年于Rush大学医学中心进行科研训练，历任博士后研究员、讲师，2023年至2024年于美国德州大学医学部任职助理教授。2024年7月起任职苏州大学基础医学院特聘教授。2024年12月起担任医学生物化学与分子生物学系系主任。
朱珂教授是国际华人骨科学会（ICMRS）终身会员。近年来以第一作者/通讯作者在Science Translational Medicine (2023), Nature Metabolism (2023), Journal of Clinical Investigation (2021), Nature Communications (2020)等国际主流期刊发表论文多篇。2014年获美国骨矿协会青年研究员Travel Grant，担任Nature Metabolism, Journal of Clinical Investigation, Journal of Clinical Endocrinology&Metabolism及Journal of Orthopaedic Translation等多个SCI杂志审稿专家。受邀在美国骨矿协会年会（ASBMR）及美国肾脏协会年会（ASN）进行口头报告 (oral presentation)。
先后主持国家自然科学基金优秀青年基金（海外）、江苏省特聘教授科研基金、苏州大学特聘教授启动资金、美国NIH R01 (因回国退出) 等。课题组与美国西北大学、伊利诺伊大学芝加哥分校、Rush大学医学中心、德州大学医学部、南方科技大学、清华大学、南开大学等国内外著名大学相关实验室建立良好的合作关系。
联系方式：kezhu@suda.edu.cn
发表论文：
1. Zhu K, Mukherjee K, Wei C, Hayek SS, Gu C, Altintas MM, Sushrut WS, Korapi K, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Sci Transl Med. 2023; 15(714):eabq6492.
2. Zhu K, Reiser J. XOR risk variants drive diabetic kidney disease. Nat Metab. 2023; 5(4):536-537.
3. Zhu K, Reiser J. ALKBH1 reduces DNA N6-methyladenine to allow forvascular calcification in chronic kidney disease. J Clin Invest. 2021; 131(14):150966.
4. Zhu K, Lai Y, Cao H, Bai X, Liu C, Yan Q, Ma L, Chen D, Kanaporis G, Wang J, Li L, Cheng T, Wang Y, Wu C, Xiao G. Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. Nat Commun. 2020; 11 (1): 484.
5. Zhu K, Song P, Lai Y, Liu C, Xiao G. Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts. Gene. 2016, 594(1): 125-130.
6. Zhu K, Yi J, Xiao Y, Lai Y, Song P, Zheng W, Jiao H, Fan J, Wu C, Chen D, Zhou J, Xiao G. Impaired bone homeostasis in amyotrophic lateral sclerosis mice with muscle atrophy. J Biol Chem. 2015, 290 (13): 8081-8094.
7. Zhu K, Jiao H, Li S, Cao H, Galson DL, Zhao Z, Zhao X, Lai Y, Fan J, Im HJ, Chen D, Xiao G. ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment. J Bone Miner Res. 2013, 28(9): 1870-84. (封面文章；骨科领域Top杂志).
8. Altintas MM, Agarwal S, Sudhini Y, Zhu K, Wei C, Reiser J. Pathogenesis of Focal Segmental Glomerulosclerosis and Related Disorders.Annu Rev Pathol. 2025; 20(1): 329-353.
9. Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Kumar VS, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J. The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. Kidney Int. 2023: S0085-2538(23)00066-2.
10. Cao H, Zhu K, Qiu L, Li S, Niu H, Hao M, Yang S, Zhao Z, Lai Y, Anderson JL, Fan J, Im HJ, Chen D, Roodman GD, Xiao G. Critical role of AKT in myeloma- induced osteoclast formation and osteolysis. J Biol Chem. 2013, 288 (42): 30399-410.
11. Zheng L, Zhu K, Jiao H, Zhao Z, Zhang L, Liu M, Deng W, Chen D, Yao Z,Xiao G. PTHrP expression in human MDA-MB-231 breast cancer cells is critical for tumor growth and survival and osteoblast inhibition. Int J Biol Sci. 2013, 9(8): 830-841.
12. Yu S, Zhu K, Lai Y, Zhao Z, Fan J, Im HJ, Chen D, Xiao G. ATF4 promotes β- Catenin expression and osteoblastic differentiation of bone marrow mesenchymal stem cells. Int J Biol Sci. 2013, 9(3): 256-266.
13. Yu S, Sharma R, Nie D, Jiao H, Im HJ, Lai Y, Zhao Z, Zhu K, Fan J, Chen D, Wang Q, Xiao G. ADAR1 ablation decreases bone mass by impairing osteoblast function in mice. Gene. 2013, 513(1): 101-10.
14. Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015; 6: 7531.
15. Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. J Clin Invest. 2019; 129 (5): 1946-1959.
16. Wei C, Zhu K, Reiser J. Soluble Urokinase Receptor and Liver Disease. Clin Liver Dis (Hoboken). 2019; 14 (5): 163-166.