李佳斌

发布时间：2026-09-10浏览次数：35

  • 1、Expedient chemical synthesis of ufmylated histones using chemoenzymatic C‑terminal hydrazinolysis of ubiquitin-fold modifier 1, ACS Chem. Biol., 2026, 21, 1146-1157
  • 2、E. coli-mediated expedient biosynthesis of biotin-labeled ubiquitin probe enables activity-based profiling of deubiquitinases in cytoplasmic and nuclear compartments, Chin. Chem. Lett., 2026, 37, 111760
  • 3、A revised model for PHF20L1 Tudor function: DNA binding overrides methylation selectivity on nucleosomes, J. Biol. Chem., 2026, 302, 113181
  • 4、Efficient chemical synthesis of multi-monoubiquitylated and diubiquitylated histones by the α halogen ketone-mediated strategy, Bioconjugate Chem., 2024, 35, 944-953
  • 5、Deubiquitinating enzyme USP39 promotes the growth and metastasis of gastric cancer cells by modulating the degradation of RNA-binding protein RBM39, J. Biol. Chem., 2024, 300, 107751
  • 6、The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1, Chem. Sci., 2023, 14, 5681-5688
  • 7、Preparation of UFM1-derived probes through highly optimized total chemical synthesis, Chem. Eur. J., 2023, 29, e202300414
  • 8、H2B Lys34 ubiquitination induces nucleosome distortion to stimulate Dot1L activity, Nat. Chem. Biol., 2022, 18, 972-980
  • 9、Chemical synthesis of post-translationally modified H2AX reveals redundancy in interplay between histone phosphorylation, ubiquitination, and methylation on the binding of 53BP1 with nucleosomes, J. Am. Chem. Soc., 2022, 144, 18329-18337
  • 10、Total chemical synthesis of bivalently modified H3 by improved three-segment native chemical ligation, Chin. Chem. Lett., 2020, 31, 1267-1270