李佳斌

发布时间：2026-02-10浏览次数：14

  • 1、Efficient chemical synthesis of multi-monoubiquitylated and diubiquitylated histones by the α halogen ketone-mediated strategy, Bioconjugate Chem., 2024, 35, 944-953
  • 2、Deubiquitinating enzyme USP39 promotes the growth and metastasis of gastric cancer cells by modulating the degradation of RNA-binding protein RBM39, J. Biol. Chem., 2024, 300, 107751
  • 3、The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1, Chem. Sci., 2023, 14, 5681-5688
  • 4、Preparation of UFM1-derived probes through highly optimized total chemical synthesis, Chem. Eur. J., 2023, 29, e202300414
  • 5、H2B Lys34 ubiquitination induces nucleosome distortion to stimulate Dot1L activity, Nat. Chem. Biol., 2022, 18, 972-980
  • 6、Chemical synthesis of post-translationally modified H2AX reveals redundancy in interplay between histone phosphorylation, ubiquitination, and methylation on the binding of 53BP1 with nucleosomes, J. Am. Chem. Soc., 2022, 144, 18329-18337
  • 7、Total chemical synthesis of bivalently modified H3 by improved three-segment native chemical ligation, Chin. Chem. Lett., 2020, 31, 1267-1270
  • 8、Cysteine-aminoethylation-assisted chemical ubiquitination of recombinant histones, J. Am. Chem. Soc., 2019, 141, 3654-3663
  • 9、Chemically synthesized histone H2A Lys13 di-ubiquitination promotes binding of 53BP1 to nucleosomes, Cell Res., 2018, 28, 257-260
  • 10、Removable backbone modification method for the chemical synthesis of membrane proteins, Acc. Chem. Res., 2017, 50, 1143-1153