元冰，苏州大学软凝聚态物理及交叉研究中心，教授，博士生导师。2004年本科毕业于山东大学，2009年于中科院物理研究所获理学博士学位，后于南京大学、新加坡国立大学、美国斯坦福大学分别进行了为期1-2年的博士后（访问）研究。主要从事细胞膜界面动力学及功能纳米复合材料相关的研究工作。在生物膜与纳米材料（蛋白质、多肽）的界面相互作用研究、以天然抗菌肽为基础的新型抗菌药物设计等领域取得了一系列创新性成果。目前的主要研究兴趣包括：(1) 细胞膜界面动力学；(2)多肽类抗耐药菌药物设计；（3）有机/无机功能纳米复合材料。具体涉及细胞内吞、多肽抗菌、药物可控搭载与释放等。
【开授课程】
普通物理（三）
普通物理-电磁学（英文，承担1/2）
仰望星空（承担1/2）
软物质物理（研究生课程，合上）
【课题组小照】
主要从事细胞膜界面动力学及功能纳米复合材料相关的研究工作。先后在J. Am. Chem. Soc.等杂志上发表论文70余篇。主持（包括结题）国家自然科学基金三项、江苏省自然科学基金两项、中国博士后科学基金两项。目前的主要研究兴趣包括：(1) 细胞膜与生物大分子的界面相互作用；(2)多肽类抗耐药菌药物设计；(3)有机/无机功能纳米复合材料。具体涉及细胞内吞、多肽抗菌、药物可控搭载与释放等。
【近期主要研究方向】
1.（以天然多肽为基础的）抗耐药菌药物设计
A molecular architectural design that promises potent antimicrobial activity against multidrug-resistant pathogens, NPG Asia Mater., 13, 18, 2021.
Designing Melittin-Graphene Hybrid Complexes for Enhanced Antibacterial Activity, Adv. Healthc. Mater., 1801521, 2019.
Graphene oxide as antibacterial sensitizer: mechanically disturbed cell membrane for enhanced poration efficiency of melittin, Carbon, 149, 248-256, 2019.
2.纳米药物的细胞内化机制及生物毒性：新设备开发&单分子研究
Photo-Voltage Transients for Real-Time Analysis of the Interactions between Molecules and Membranes, ACS Appl. Bio Mater., 4(1), 620-629, 2021.
Membrane perturbation of fullerene and graphene oxide distinguished by pore-forming peptide melittin,Carbon, 180, 67-76, 2021.
Correlation between single-molecule dynamics and biological functions of antimicrobial peptide melittin, J. Phys. Chem. Lett., 11, 4834-4841, 2020.
Cardiolipin Selectively Binds to the Interface of VsSemiSWEET and Regulates Its Dimerization, J. Phys. Chem. Lett., 12, 1940-1946, 2021.
Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model, Small, 12(9), 1140-1146, 2016.
3.（生物膜）功能纳米复合材料
Modulated enhancement in ion transport through carbon nanotubes by lipid decoration, Carbon, 111, 459-466, 2017.
Modulated deformation of lipid membrane to vesicles and tubes due to reduction of graphene oxide substrate under laser irradiation, Carbon, 98, 300-306, 2016.
Self-assembly of highly oriented lamellar nanoparticle-phospholipid nanocomposites on solid surfaces, J. Am. Chem. Soc., 129 (37): 11332, 2007.
【部分论文列表】
[68] Kejie He†, Yushuang Wei†, Zhihong Zhang, Haibo Chen, Bing Yuan*, Hong-Bo Pang* and Kai Yang*, Membrane-curvature-mediated co-endocytosis of bystander and functional nanoparticles, Nanoscale, 2021, in press.
[67] Che Zhang,† Yuke Ge,† Xuemei Lu,† Zhonglan Chen,† Jiaojiao Liu, Mengling Zhang, Kai Yang,* Bing Yuan*, Membrane perturbation of fullerene and graphene oxide distinguished by pore-forming peptide melittin, Carbon, 180, 67-76, 2021.
[66] Zhihong Zhang, Wendong Ma, Kejie He, Bing Yuan* and Kai Yang*, Ligand-Decoration Determines the Translational and Rotational Dynamics of Nanoparticles on a Lipid Bilayer Membrane, Phys. Chem. Chem. Phys., 23, 9158-9165, 2021.
[65] Zhonglan Chen#, Xuemei Lu#, Jiaojiao Liu#, Xiaodong Tian, Wenwen Li, Kai Yang*, Bing Yuan*, Lipid Phase Influences the Dynamic Interactions between Graphene Oxide Nanosheets and a Phospholipid Membrane, J. Phys. Chem. B, 125, 14, 3589–3597, 2021.
[64] Bing Yuan, Jiaojiao Liu, Zhixiong Deng, Lin Wei, Wenwen Li, Yujiang Dou, Zhonglan Chen, Che Zhang, Yu Xia, Mengling Zhang, Kai Yang*, Yuqiang Ma*, Zhenhui Kang*, Designed molecular architecture promises potent antimicrobial activity against multidrug-resistant pathogens, NPG Asia Mater., 13, 18, 2021.
[63] Zhixiong Deng, Bing Yuan*, Kai Yang*, Cardiolipin Selectively Binds to the Interface of VsSemiSWEET and Regulates Its Dimerization, J. Phys. Chem. Lett., 12, 1940-1946, 2021.
[62] Yujiang Dou#, Wenwen Li#, Yu Xia#, Zhonglan Chen, Zhenyu Wu, Yuke Ge, Zhao Lin, Mengling Zhang, Kai Yang, Bing Yuan*, Zhenhui Kang*, Photo-voltage transients for real-time analysis of the interactions between molecules and membranes, ACS Appl. Bio Mater., 4(1), 620-629, 2021.
[61] Jia Li, Xuemei Lu, Wendong Ma, Zhonglan Chen, Shuqing Sun, Qinghui Wang, Bing Yuan*, Kai Yang*, Cholesterols work as a molecular regulator of the antimicrobial peptide-membrane interactions, Front. Mol. Biosci., 8:638988. doi: 10.3389/fmolb.2021.638988, 2021.
[60] Wenwen Li#, Zhao Lin#, Bing Yuan*, Kai Yang*, Tail-Structure Regulated Phase Behaviors of a Lipid Bilayer, Chinese Phys. B, 29(12), 128701, 2020.
[59] 鲍美美, 杨恺*, 元冰*, Influenza virus and coronavirus: cellular binding and internalization. Acta Phys. Sin., 69(20), 208701, 2020. 流感病毒和冠状病毒的细胞表面结合与内化, 物理学报 (Review)
[58] Wendong Ma, Shuqing Sun, Wenwen Li, Zhihong Zhang, Zhao Lin, Yu Xia, Bing Yuan* and Kai Yang*, Individual Roles of Peptides PGLa and Magainin 2 in Synergistic Membrane Poration, Langmuir, 36, 26, 7190-7199, 2020.
[57] Cheng Xu#, Wendong Ma#, Kang Wang, Kejie He, Zhonglan Chen, Jiaojiao Liu, Kai Yang* and Bing Yuan*, Correlation between single-molecule dynamics and biological functions of antimicrobial peptide melittin, J. Phys. Chem. Lett., 11, 4834-4841, 2020.
[56] Xu Cheng, Lin Zhao, Yang Kai* and Yuan Bing*, Single molecular kinetics during the interactions between melittin and a bi-component lipid membrane, Acta Phys. Sin., 69(10), 108701, 2020.
[55] Zhixiong Deng, Xuemei Lu, Cheng Xu, Bing Yuan* and Kai Yang*, Lipid-Specific Interactions Determine the Organization and Dynamics of Membrane-Active Peptide Melittin, Soft Matter, 16, 3498-3504, 2020.
[54] Jiajia Hong, Xuemei Lu, Zhixiong Deng, Shufeng Xiao, Bing Yuan*, Kai Yang*, How Melittin Inserts into Cell Membrane: Conformational Changes, Inter-Peptide Cooperation, and Disturbance on the Membrane, Molecules 24(9), 1775, 2019. (Review)
[53] Zhixiong Deng, Jingliang Li, Bing Yuan*, Kai Yang*, Residue-specialized Membrane Poration Kinetics of Melittin and Its Variants: Insight from Mechanistic Landscapes, Commun. Theor. Phys.71, 887-902, 2019.
[52] Shufeng Xiao#, Xuemei Lu#, Lu Gou#, Jingliang Li, Yuqiang Ma, Jiaojiao Liu*, Kai Yang*, Bing Yuan*，Graphene oxide as antibacterial sensitizer: mechanically disturbed cell membrane for enhanced poration efficiency of melittin, Carbon, 149, 248-256, 2019.
[50] Kai Yang, Ran Yang, Xiaodong Tian, Kejie He, Seth Leon Filbrun, Ning Fang, Yu-qiang Ma, Bing Yuan*, Partitioning of nanoscale particles on a heterogeneous multicomponent lipid bilayer, Phys. Chem. Chem. Phys., 20, 28241-28248, 2018.
[49] Jiaojiao Liu, Shufeng Xiao, Jingliang Li, Bing Yuan*, Kai Yang*, Yuqiang Ma, Molecular details on the intermediate states of melittin action on a cell membrane, BBA-Biomembranes, 1860, 2234-2241, 2018.
[48] Jiaojiao Liu#, Bin Song#, Jingliang Li, Xiaodong Tian, Yuqiang Ma, Kai Yang*, Bing Yuan*, Photoluminescence modulation of silicon nanoparticles via highly ordered arrangement with phospholipid membranes, Colloids and Surfaces B: Biointerfaces, 170, 656-662, 2018.
[47] Wenbin Wang, Ran Yang, Fei Zhang, Bing Yuan*, Kai Yang*, Yuqiang Ma, Partner-facilitating transmembrane penetration of nanoparticles: a biological test in Silico, Nanoscale, 10, 11670-11678, 2018.
[46] Jing-Yu Chen, Zahra Komeily-Nia, Lin-Peng Fan, Zhen-Yu Li, Bing Yuan, Bin Tang, Jing-Liang Li*, Manipulating the fractal fiber network of a molecular gel with surfactants, Journal of Colloid and Interface Science, 526, 356–365, 2018.
[45] Jiaojiao Liu#, Qi Chang#, Meimei Bao, Bing Yuan*, Kai Yang*, Yuqiang Ma, “Silicon Quantum Dots Delivered Phthalocyanine for Fluorescence Guided Photodynamic Therapy of Tumor”, Chin. Phys. B, 26(9), 098102, 2017.
[44] Zahra Komeily Nia, Jingyu Chen, Bing Yuan, Bin Tang, Jingliang Li*, “Optimizing the free radical content of graphene oxide by controlling its reduction”, Carbon, 116, 703-712, 2017.
[43] Jiaojiao Liu, Rui Wang, Sicong Wu, Bing Yuan*, Meimei Bao, Jingliang Li, Yujiang Dou, Yao He* and Kai Yang*, “One-pot synthesis of silicon based nanoparticles with incorporated phthalocyanine for long-term bioimaging and photo-dynamic therapy of tumors”, Nanotechnology, 28(13), 135601, 2017.
[42] Ye Li, Bing Yuan, Kai Yang, Xianren Zhang, Bing Yan, Dapeng Cao*, Counterintuitive Cooperative Endocytosis of like-charged Nanoparticles in Cellular Internalization: Computer Simulation and Experiment, Nanotechnology, DOI: 10.1088/1361-6528/aa56e0, 2017.
[41] Bing Yuan*, Xiangxu Jiang, Chu Yao, Meimei Bao, Jiaojiao Liu, Yujiang Dou, Yinze Xu, Yao He*, Kai Yang*, Yuqiang Ma, “Plasmon-enhanced fluorescence imaging with silicon-based silver chips for protein and nucleic acid assay”, Anal. Chim. Acta, 955, 98-107, 2017.
[40] Jiaojiao Liu#, Xiaodong Tian#, Meimei Bao, Jingliang Li, Yujiang Dou, Bing Yuan*, Kai Yang*, Yuqiang Ma, Manipulation of cellular orientation and migration by internalized magnetic particles, Mater. Chem. Front., DOI: 10.1039/c6qm00219f, 2017.
[39] Xue-mei Lu, Bing Yuan*, Xian-ren Zhang, Kai Yang*, and Yu-qiang Ma, “Molecular modeling of transmembrane delivery of paclitaxel by shock waves with nanobubbles”, Appl. Phys. Lett., 110, 023701, 2017. (封面文章)
[38] Jiaojiao Liu, Bing Yuan*, Xuewu Wu, Jingliang Li, Fangming Han, Yujiang Dou, Muzi Chen, Zhaohui Yang*, Kai Yang*, and Yuqiang Ma, “Modulated enhancement in ion transport through carbon nanotubes by lipid decoration”, Carbon, 111, 459-466, 2017.
[37] Jing-Yu Chen, Bing Yuan, Zhen-Yu Li, Bin Tang, Akhil Gupta, Sheshanath-Vishwanath Bhosale, Jing-Liang Li*, “Synergistic coassembly of two structurally different molecular gelators”, Langmuir, 32, 12175–12183, 2016.
[36] Jingyu Chen, Bing Yuan, Zhenyu Li, Bin Tang, Elizabeth Ankers, Xungai Wang, Jing Liang Li, “Controlling the supramolecular architecture of molecular gels with surfactants”, Langmuir, 32 (4), 1171–1177, 2016.
[35] Byumseok Koh, Xiaoyang Li, Bo Zhang, Bing Yuan, Yi Lin, Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, Yongye Liang, and Hongjie Dai*, “Visible to Near-Infrared Fluorescence Enhanced Cellular Imaging on Plasmonic Gold Chips”, Small, 12(4), 457-465, 2016.
[34] Jiaojiao Liu, Meimei Bao, Jingliang Li, YuyanWeng, Yujiang Dou, Bing Yuan*, Kai Yang, Yuqiang Ma*, “Modulated Deformation of Lipid Membrane to Vesicles and Tubes due to Reduction of Graphene Oxide Substrate under Laser Irradiation”, Carbon, 98, 300-306, 2016.
[33] Qiuju Ji#, Bing Yuan#, Xuemei Lu, Kai Yang*, and Yuqiang Ma*, Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model, Small, 12(9), 1140-1146, 2016. (封面文章)
[32] Hao Yang, Ling Wang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Adhesion of an Ultrasmall Nanoparticle on a Bilayer Membrane is Still Size and Shape Dependent, J. Mater. Sci. Technol., 31, 660-663, 2015.
[31] Haizhen Zhang, Qiuju Ji, Changjin Huang, Sulin Zhang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Cooperative Transmembrane Penetration of Nanoparticles, Sci. Rep., 5, 10525, 2015.
[30] Fan Xu, Meimei Bao, Longfei Rui, Jiaojiao Liu, Jingliang Li, Yujiang Dou, Kai Yang, Bing Yuan*, and Yuqiang Ma*, Self-assembly of Monolayered Lipid Membranes for Surface coating of a Nanoconfined Bombyx Mori Silk Fibroin Film, RSC Advances, 5, 65684-65689, 2015.
[29] Longfei Rui, Jiaojiao Liu, Jingliang Li, Yuyan Weng, Yujiang Dou, Bing Yuan*, Kai Yang, Yuqiang Ma*, Reduced Graphene Oxide Directed Self-Assembly of Phospholipid Monolayers in Liquid and Gel Phases, BBA – Biomembranes, 1848, 1203-1211, 2015
[28] Haizhen Zhang, Ling Wang, Bing Yuan, Kai Yang*, Yuqiang Ma, “Effect of receptor structure and length on the wrapping of a nanoparticle by a lipid membrane”, Materials, 7(5), 3855-3866, 2014
[27] Jiaojiao Liu, Jingliang Li, Zexin Zhang, Yuyan Weng, Gaojian Chen, Bing Yuan*, Kai Yang and Yuqiang Ma*, Encapsulation of Hydrophobic Phthalocyanine with Poly(N-isopropylacrylamide)/Lipid Composite Microspheres for Thermo-Responsive Release and Photodynamic Therapy, Materials, 7(5), 3481-3493, 2014
[26] Naiyan Lu, Jiaojiao Liu, Jingliang Li, Zexin Zhang, Yuyan Weng, Bing Yuan*, Kai Yang and Yuqiang Ma*, Tunable Dual-stimuli Response of a Microgel Composite Consisting of Reduced Graphene Oxide Nanoparticles and Poly(N-isopropylacrylamide) Hydrogel Microsphere, J. Mater. Chem. B, 2(24), 3791-3798, 2014
[25] Yu Liu, Rong-Yao Wang*, Jing-Liang Li, Bing Yuan, Min Han, Peng Wang, Xiang-Yang Liu, Identify Kinetic Features of Fibers Growing, Branching, and Bundling in Microstructure Engineering of Crystalline Fiber Network, Crys. Eng. Comm., 16, 5402-5408, 2014
[24] Yujiang Dou, Jingliang Li, Bing Yuan*, Kai Yang*, Lipid Merging, Protrusion and Vesicle Release Triggered by Shrinking/swelling of Poly(N-isopropylacrylamide) Microgel Particles, Appl. Surf. Sci., 296, 95-99, 2014
[23] Jingliang Li, Bin Tang, Bing Yuan, Lu Sun, Xungai Wang*, A review of optical imaging and therapy using nanosized graphene and graphene oxide, Biomaterials, 34, 9519-9534, 2013
[22] Naiyan Lu, Bing Yuan*, Kai Yang*, Nonspecific adsorption of charged mesoporous nanoparticles on supported thiol/lipid hybrid bilayers, Acta Phys. Sin., 62(17), 178701, 2013
[21] Naiyan Lu, Kai Yang; Jingliang Li; Yuyan Weng, Bing Yuan*, Yuqiang Ma*, Controlled Drug Loading and Release of a Stimuli-responsive Lipogel Consisting of Poly(N-isopropylacrylamide) Particle and Lipids,J. Phys. Chem. B, 117, 9677-9682, 2013
[20] Kai Yang, Bing Yuan*, Yuqiang Ma*, Influence of geometric nanoparticle’s rotation on cellular internalization Process, Nanoscale, 5, 7998-8006, 2013
[19] Jiaojiao Liu, Naiyan Lu, Jingliang Li, Yuyan Weng, Bing Yuan*, Kai Yang*,Yuqiang Ma, Influence of Surface Chemistry on Particle Internalization into Giant Unilamellar Vesicles, Langmuir, 29(25), 8039-8045, 2013
[18] Nai-Yan Lu; Kai Yang; Jing-Liang Li; Bing Yuan*; Yu-Qiang Ma*, Vesicle Deposition and Subsequent Membrane-melittin Interactions on Different Substrates: a QCM-D Experiment, BBA – Biomembranes, 1828(8), 1918-1925, 2013
[17] Rong-Yao Wang, Peng Wang, Jing-Liang Li, Bing Yuan, Yu Liu, Li Li, and Xiang-Yang Liu, From Kinetics-structure Analysis to Engineering Crystalline Fiber Network in Soft Materials, Phys. Chem. Chem. Phys., 15, 3313-3319, 2013
[16] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, Rong-Yao Wang, and Xun-Gai Wang, Control of crystallization in supramolecular soft materials engineering, Soft Matter, 9, 435-442, 2013
[15] Naiyan Lu, Kai Yang, Bing Yuan* and Yuqiang Ma*, Molecular Response and Cooperative Behavior during the Interactions of Melittin with a Membrane: Dissipative Quartz Crystal Microbalance Experiments and Simulations, J. Phys. Chem. B, 116, 9432-9438, 2012
[14] Kai Yang, Bing Yuan and Yuqiang Ma, “Curvature Changes of Bilayer Membranes Studied by Computer Simulations”,J. Phys. Chem. B, 116, 7196-7202, 2012
[13] Bing Yuan, Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma and Ying-Jun Wang, “Size invariance of fibrous networks of supramolecular soft materials during formation under critical volume confinement”, Soft Matter, 8(19), 5187-5193, 2012
[12] Tao Zhu, Fan Xu, Bing Yuan, Chunlai Ren, Zhongying Jiang and Yuqiang Ma, “Effect of calcium cation on lipid vesicle deposition on silicon dioxide surface under various thermal conditions”, Colloid Surface B, 89, 228-233, 2012
[11] Bing Yuan, Shu-Xin Hu, Nai-Yan Lu, Fan Xu, Kun Zhou, Yu-Qiang Ma, and Ming Li, “Electrical bistability in self-assembled hybrid multilayers of phospholipid and nanoparticles”,Nanotechnology, 22(31): 315303, 2011
[10] Bing Yuan*, Ze-Xin Zhang*, and Kun Zhou, “Graphene oxide monolayers as supporting films for high resolution transmission electron microscopy”,Appl. Surf. Sci., 257(13): 5754-5758, 2011
[9] Bing Yuan, Tao Zhu, Zexin Zhang, Zhongying Jiang, and Yuqiang Ma, “Self-assembly of multilayered functional films based on graphene oxide sheets for controlled release”,J. Mater. Chem., 21(10): 3471-3476, 2011
[8] Bing Yuan, Xiang-Yang Liu, Jing-Liang Li, and Hong-Yao Xu, “Volume Confinement Induced Microstructural Transition and Property Enhancement of Supramolecular Soft Materials”, Soft Matter, 7(5): 1708-1713, 2011
[7] Bing Yuan, Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma, and Hong-Yao Xu, “Critical behavior of confined supramolecular soft materials in microscopic scale”,Chem. Commun., 47(10): 2793-2795, 2011 (Hot article, and featured by the editor)
[6] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, and Rong-Yao Wang, “Kinetically controlled homogenization and transformation of crystalline fiber networks in supramolecular materials”, Crystal Growth & Design, 11(7), 3227-3234, 2011
[5] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, and Hong-Yao Xu, “Microengineering of Supramolecular Soft Materials by Design of the Crystalline Fiber Networks”, Crystal Growth & Design, 10(6), 2699-2706, 2010
[4] Yu-Dong Zhang, Shu-Xin Hu, Bing Yuan, Xi-Miao Hou, Ying Lu, and Ming Li, “Subnanometer-Thick PbS Film on Organic Substrate and Its Usage as Buffer for Homo- and Heteroepitaxial Overgrowth”, Langmuir, 25(10), 5609-5613, 2009
[3] Li-Li Xing, Bing Yuan, Shu-Xin Hu, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Electrochemical Synthesis of Highly Oriented Layered Zinc Hydroxide with Intercalated p-Aminobenzoic Acid”, J. Phys. Chem. C, 112(10), 3800-3804, 2008
[2] Bing Yuan, Li-Li Xing, Yu-Dong Zhang, Ying Lu, Yi-Yong Luo, Zhen-Hong Mai, and Ming Li, “Penetration and saturation of lysozyme in phospholipid bilayers”, J. Phys. Chem. B, 111 (22): 6151-6155, 2007
[1] Bing Yuan, Li-Li Xing, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Self-assembly of highly oriented lamellar nanoparticle-phospholipid nanocomposites on solid surfaces”, J. Am. Chem. Soc., 129 (37): 11332, 2007
【专利】
[6]《一种采用抗菌肽和富勒烯联合抗菌方法》，申请号/专利号：202010131067.4，申请日：2020.02.28
[5]《一种基于抗菌肽和亲水聚合物的抗菌药物及制备方法》，申请号/专利号：202010129914.3，申请日：2020.02.28
[4]《一种抗菌肽复合材料及其制备方法与应用》，申请号/专利号：2018110620367，申请日：2018.09.12
[3]《温敏性杂化颗粒药物载体及其制备方法和应用》，申请（专利）号201510989352.9，申请日2015.12.25
[2]《透射电子显微镜样品支撑膜和透射电子显微镜样品的制作方法》，申请（专利）号201110040813.X，申请日2011.02.18
[1]《氧化石墨烯/溶菌酶抗菌纳米复合薄膜材料、其制备方法及作为抗菌材料的应用》，申请（专利）号ZL201010610000.5，申请日2010.12.29
1. 生物膜与界面
1) 生物膜在固体表面的自组装及响应重组
2) 纳米颗粒的跨膜内吞
3) 生物膜与蛋白质的界面相互作用：抗菌肽的分子作用机制及微结构设计
2. 功能纳米复合材料
1) 纳米颗粒的长程有序排布及性质调制
2) 智能杂化材料的可控释放
3) 药物搭载与肿瘤治疗
3. 细胞行为调控
图例：
1. 生物膜与界面
1) 生物膜在固体表面的自组装及响应重组
Carbon,98, 300-306, 2016
Appl. Surf.Sci., 296, 95-99, 2014
Carbon,111, 459-466, 2017
2) 纳米颗粒的跨膜内吞
Langmuir,29(25), 8039-8045, 2013
Sci.Rep., 5, 10525, 2015
Small,12(9), 1140-1146, 2016 (封面文章)
Appl.Phys. Lett., 110, 023701, 2017 (封面文章)
3) 生物膜与蛋白质的界面相互作用：抗菌肽的分子作用机制及微结构设计
2. 功能纳米复合材料
1) 纳米颗粒的长程有序排布
J. Am.Chem. Soc., 129 (37): 11332, 2007
Nanotechnology, 22(31), 315303, 2011
2) 智能杂化材料的可控释放
J. Mater. Chem., 21(10), 3471-3476, 2011
J. Mater.Chem. B, 2(24), 3791-3798, 2014
3) 药物搭载与肿瘤治疗
Nanotechnology, 28(13),135601, 2017
3. 细胞行为调控
Mater.Chem. Front., DOI:10.1039/c6qm00219f, 2017
与杨恺教授合作，构建了以“实验与模拟相结合”为特色的研究队伍。
王瑞（硕士）毕业留影，2017
刘娇娇（博士）毕业答辩, 2017
卢雪梅（硕士）毕业留影，2017
普通物理（三）
普通物理-电磁学（英文，承担1/2）
仰望星空（承担1/2）
软物质物理（研究生课程，合上）
【本科生项目】
2019年省级大学生创新创业训练计划项目（陆琰洲，周珂儿，刘之恒）
2019年科学前沿创新实践I（马宗光）
2018年莙政基金项目（鞠煜）
2017年江苏省高校第十四届大学生物理及实验科技作品创新竞赛（常琪；一等奖）
2016年校级大学生创新创业训练计划项目（常琪，燕婧文，徐可；优秀等级）
2013年省级大学生创新创业训练计划项目（张燕南等；2/2）
[50]Kai Yang, Ran Yang, Xiaodong Tian, Kejie He, Seth Leon Filbrun, Ning Fang,Yu-qiang Ma, Bing Yuan*,Partitioning of nanoscale particles on a heterogeneous multicomponent lipidbilayer, Physical Chemistry Chemical Physics, 20, 28241-28248, 2018.
[49] Jiaojiao Liu, ShufengXiao, Jingliang Li, Bing Yuan*, KaiYang*, Yuqiang Ma, Molecular details on the intermediate states of melittinaction on a cell membrane, BBA-Biomembranes, 1860, 2234-2241, 2018.
[48] Jiaojiao Liu#, BinSong#, Jingliang Li, Xiaodong Tian, Yuqiang Ma, Kai Yang*, Bing Yuan*, Photoluminescence modulation of silicon nanoparticlesvia highly ordered arrangement with phospholipid membranes, Colloidsand Surfaces B: Biointerfaces, 170, 656-662, 2018.
[47] Wenbin Wang, Ran Yang,Fei Zhang, Bing Yuan*, Kai Yang*,Yuqiang Ma, Partner-facilitating transmembrane penetration of nanoparticles: abiological test in Silico, Nanoscale, 10, 11670-11678, 2018.
[46] Jing-Yu Chen, ZahraKomeily-Nia, Lin-Peng Fan, Zhen-Yu Li, BingYuan, Bin Tang, Jing-Liang Li*, Manipulating the fractal fiber network of amolecular gel with surfactants, Journalof Colloid and Interface Science, 526, 356–365, 2018.
[45] Jiaojiao Liu#, QiChang#, Meimei Bao, Bing Yuan*, KaiYang*, Yuqiang Ma, “Silicon Quantum Dots Delivered Phthalocyanine forFluorescence Guided Photodynamic Therapy of Tumor”, Chin. Phys. B, 26(9),098102, 2017.
[44] Zahra Komeily Nia,Jingyu Chen, Bing Yuan, Bin Tang,Jingliang Li*, “Optimizing the free radical content of graphene oxide bycontrolling its reduction”, Carbon, 116, 703-712, 2017.
[43] Jiaojiao Liu, RuiWang, Sicong Wu, Bing Yuan*, MeimeiBao, Jingliang Li, Yujiang Dou, Yao He* and Kai Yang*, “One-pot synthesis ofsilicon based nanoparticles with incorporated phthalocyanine for long-termbioimaging and photo-dynamic therapy of tumors”, Nanotechnology, 28(13),135601, 2017.
[42] Ye Li, Bing Yuan, Kai Yang, Xianren Zhang,Bing Yan, Dapeng Cao*, Counterintuitive Cooperative Endocytosis of like-chargedNanoparticles in Cellular Internalization: Computer Simulation and Experiment, Nanotechnology, DOI:10.1088/1361-6528/aa56e0, 2017.
[41] Bing Yuan*, Xiangxu Jiang, Chu Yao, Meimei Bao, Jiaojiao Liu,Yujiang Dou, Yinze Xu, Yao He*, Kai Yang*, Yuqiang Ma, “Plasmon-enhancedfluorescence imaging with silicon-based silver chips for protein and nucleicacid assay”, Anal. Chim. Acta, 955, 98-107, 2017.
[40] Jiaojiao Liu#,Xiaodong Tian#, Meimei Bao, Jingliang Li, Yujiang Dou, Bing Yuan*, Kai Yang*, Yuqiang Ma, Manipulation of cellular orientation andmigration by internalized magnetic particles, Mater.Chem. Front., DOI: 10.1039/c6qm00219f, 2017.
[39] Xue-mei Lu, Bing Yuan*, Xian-ren Zhang, Kai Yang*,and Yu-qiang Ma, “Molecular modeling of transmembrane delivery of paclitaxel byshock waves with nanobubbles”, Appl. Phys. Lett., 110, 023701, 2017.(封面文章)
[38] Jiaojiao Liu, Bing Yuan*, Xuewu Wu, Jingliang Li, FangmingHan, Yujiang Dou, Muzi Chen, Zhaohui Yang*, Kai Yang*, and Yuqiang Ma,“Modulated enhancement in ion transport through carbon nanotubes by lipiddecoration”, Carbon, 111, 459-466, 2017.
[37] Jing-Yu Chen, Bing Yuan, Zhen-Yu Li, Bin Tang, AkhilGupta, Sheshanath-Vishwanath Bhosale, Jing-Liang Li*, “Synergistic coassemblyof two structurally different molecular gelators”, Langmuir, 32,12175–12183, 2016.
[36] Jingyu Chen, Bing Yuan, Zhenyu Li, Bin Tang,Elizabeth Ankers, Xungai Wang, Jing Liang Li, “Controlling the supramoleculararchitecture of molecular gels with surfactants”, Langmuir, 32 (4),1171–1177, 2016.
[35] Byumseok Koh, XiaoyangLi, Bo Zhang, Bing Yuan, Yi Lin,Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, YongyeLiang, and Hongjie Dai*, “Visible to Near-Infrared Fluorescence EnhancedCellular Imaging on Plasmonic Gold Chips”, Small, 12(4), 457-465, 2016.
[34] Jiaojiao Liu, MeimeiBao, Jingliang Li, YuyanWeng, Yujiang Dou, Bing Yuan*, Kai Yang, YuqiangMa*, “Modulated Deformation of Lipid Membrane to Vesicles and Tubes due toReduction of Graphene Oxide Substrate under Laser Irradiation”, Carbon,98, 300-306, 2016.
[33] Qiuju Ji#, BingYuan#, Xuemei Lu, Kai Yang*, and Yuqiang Ma*, Controlling theNanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: AComputational Model, Small, 12(9), 1140-1146, 2016. (封面文章)
[32] Hao Yang, Ling Wang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Adhesionof an Ultrasmall Nanoparticle on a Bilayer Membrane is Still Size and ShapeDependent, J. Mater. Sci. Technol., 31, 660-663, 2015.
[31] Haizhen Zhang, QiujuJi, Changjin Huang, Sulin Zhang, BingYuan, Kai Yang*, and Yuqiang Ma*, Cooperative Transmembrane Penetration ofNanoparticles, Sci. Rep., 5, 10525, 2015.
[30] Fan Xu, Meimei Bao,Longfei Rui, Jiaojiao Liu, Jingliang Li, Yujiang Dou, Kai Yang, Bing Yuan*,and Yuqiang Ma*, Self-assembly of Monolayered Lipid Membranes for Surfacecoating of a Nanoconfined Bombyx Mori Silk Fibroin Film, RSC Advances,5, 65684-65689, 2015.
[29] Longfei Rui, JiaojiaoLiu, Jingliang Li, Yuyan Weng, Yujiang Dou, Bing Yuan*, Kai Yang,Yuqiang Ma*, Reduced Graphene Oxide Directed Self-Assembly of PhospholipidMonolayers in Liquid and Gel Phases, BBA – Biomembranes, 1848,1203-1211, 2015
[28] Haizhen Zhang, LingWang, Bing Yuan, Kai Yang*, YuqiangMa, “Effect of receptor structure and length on the wrapping of a nanoparticleby a lipid membrane”, Materials, 7(5), 3855-3866, 2014
[27] Jiaojiao Liu,Jingliang Li, Zexin Zhang, Yuyan Weng, Gaojian Chen, Bing Yuan*, KaiYang and Yuqiang Ma*, Encapsulation of Hydrophobic Phthalocyanine withPoly(N-isopropylacrylamide)/Lipid Composite Microspheres for Thermo-ResponsiveRelease and Photodynamic Therapy, Materials, 7(5), 3481-3493,2014
[26] Naiyan Lu, JiaojiaoLiu, Jingliang Li, Zexin Zhang, Yuyan Weng, Bing Yuan*, Kai Yang andYuqiang Ma*, Tunable Dual-stimuli Response of a Microgel Composite Consistingof Reduced Graphene Oxide Nanoparticles and Poly(N-isopropylacrylamide)Hydrogel Microsphere, J. Mater. Chem. B, 2(24), 3791-3798, 2014
[25] Yu Liu, Rong-YaoWang*, Jing-Liang Li, BingYuan, Min Han, Peng Wang, Xiang-Yang Liu, Identify KineticFeatures of Fibers Growing, Branching, and Bundling in MicrostructureEngineering of Crystalline Fiber Network, Crys. Eng. Comm., 16, 5402-5408, 2014
[24] Yujiang Dou, JingliangLi, Bing Yuan*, Kai Yang*, Lipid Merging, Protrusion and Vesicle Release Triggered byShrinking/swelling of Poly(N-isopropylacrylamide) Microgel Particles, Appl. Surf. Sci.,296, 95-99, 2014
[23] Jingliang Li, BinTang, Bing Yuan,Lu Sun, Xungai Wang*, A review of optical imaging and therapy using nanosizedgraphene and graphene oxide, Biomaterials,34, 9519-9534, 2013
[22] Naiyan Lu, Bing Yuan*, Kai Yang*,Nonspecific adsorption of charged mesoporous nanoparticles on supportedthiol/lipid hybrid bilayers, ActaPhys. Sin., 62(17), 178701, 2013
[21] Naiyan Lu, Kai Yang;Jingliang Li; Yuyan Weng, Bing Yuan*, Yuqiang Ma*, Controlled DrugLoading and Release of a Stimuli-responsive Lipogel Consisting ofPoly(N-isopropylacrylamide) Particle and Lipids,J. Phys. Chem. B,117, 9677-9682, 2013
[20] Kai Yang, Bing Yuan*,Yuqiang Ma*, Influence of geometric nanoparticle’s rotation on cellularinternalization Process, Nanoscale, 5, 7998-8006, 2013
[19] Jiaojiao Liu, NaiyanLu, Jingliang Li, Yuyan Weng, Bing Yuan*, Kai Yang*,YuqiangMa, Influence of Surface Chemistry on Particle Internalization into GiantUnilamellar Vesicles, Langmuir, 29(25), 8039-8045, 2013
[18] Nai-Yan Lu; Kai Yang;Jing-Liang Li; Bing Yuan*; Yu-Qiang Ma*, Vesicle Deposition andSubsequent Membrane-melittin Interactions on Different Substrates: a QCM-DExperiment, BBA – Biomembranes, 1828(8), 1918-1925, 2013
[17] Rong-Yao Wang, PengWang, Jing-Liang Li, Bing Yuan, Yu Liu, Li Li, and Xiang-Yang Liu, FromKinetics-structure Analysis to Engineering Crystalline Fiber Network in SoftMaterials, Phys. Chem. Chem. Phys., 15, 3313-3319, 2013
[16] Jing-Liang Li, BingYuan, Xiang-Yang Liu, Rong-Yao Wang, and Xun-Gai Wang, Control ofcrystallization in supramolecular soft materials engineering, Soft Matter,9, 435-442, 2013
[15] Naiyan Lu, Kai Yang, BingYuan* and Yuqiang Ma*, Molecular Response and Cooperative Behavior duringthe Interactions of Melittin with a Membrane: Dissipative Quartz CrystalMicrobalance Experiments and Simulations, J. Phys. Chem. B, 116,9432-9438, 2012
[14] Kai Yang, Bing Yuan and Yuqiang Ma, “Curvature Changes of Bilayer Membranes Studied by ComputerSimulations”,J. Phys. Chem. B, 116, 7196-7202, 2012
[13] Bing Yuan,Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma and Ying-Jun Wang, “Size invarianceof fibrous networks of supramolecular soft materials during formation undercritical volume confinement”, Soft Matter, 8(19), 5187-5193, 2012
[12] Tao Zhu, Fan Xu, BingYuan, Chunlai Ren, Zhongying Jiang and Yuqiang Ma, “Effect of calciumcation on lipid vesicle deposition on silicon dioxide surface under variousthermal conditions”, Colloid Surface B, 89, 228-233, 2012
[11] Bing Yuan,Shu-Xin Hu, Nai-Yan Lu, Fan Xu, Kun Zhou, Yu-Qiang Ma, and Ming Li, “Electricalbistability in self-assembled hybrid multilayers of phospholipid andnanoparticles”,Nanotechnology, 22(31): 315303, 2011
[10] Bing Yuan*,Ze-Xin Zhang*, and Kun Zhou, “Graphene oxide monolayers as supporting films forhigh resolution transmission electron microscopy”,Appl. Surf. Sci.,257(13): 5754-5758, 2011
[9] Bing Yuan, TaoZhu, Zexin Zhang, Zhongying Jiang, and Yuqiang Ma, “Self-assembly ofmultilayered functional films based on graphene oxide sheets for controlledrelease”,J. Mater. Chem., 21(10): 3471-3476, 2011
[8] Bing Yuan,Xiang-Yang Liu, Jing-Liang Li, and Hong-Yao Xu, “Volume Confinement InducedMicrostructural Transition and Property Enhancement of Supramolecular SoftMaterials”, Soft Matter, 7(5): 1708-1713, 2011
[7] Bing Yuan,Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma, and Hong-Yao Xu, “Critical behaviorof confined supramolecular soft materials in microscopic scale”,Chem.Commun., 47(10): 2793-2795, 2011 (Hot article, and featured by theeditor)
[6] Jing-Liang Li, BingYuan, Xiang-Yang Liu, and Rong-Yao Wang, “Kinetically controlledhomogenization and transformation of crystalline fiber networks insupramolecular materials”, Crystal Growth & Design, 11(7),3227-3234, 2011
[5] Jing-Liang Li, BingYuan, Xiang-Yang Liu, and Hong-Yao Xu, “Microengineering of SupramolecularSoft Materials by Design of the Crystalline Fiber Networks”, CrystalGrowth & Design, 10(6), 2699-2706, 2010
[4] Yu-Dong Zhang, Shu-XinHu, Bing Yuan, Xi-Miao Hou, Ying Lu, and Ming Li, “Subnanometer-ThickPbS Film on Organic Substrate and Its Usage as Buffer for Homo- andHeteroepitaxial Overgrowth”, Langmuir, 25(10), 5609-5613, 2009
[3] Li-Li Xing, BingYuan, Shu-Xin Hu, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li,“Electrochemical Synthesis of Highly Oriented Layered Zinc Hydroxide withIntercalated p-Aminobenzoic Acid”, J. Phys. Chem. C, 112(10),3800-3804, 2008
[2] Bing Yuan, Li-LiXing, Yu-Dong Zhang, Ying Lu, Yi-Yong Luo, Zhen-Hong Mai, and Ming Li,“Penetration and saturation of lysozyme in phospholipid bilayers”, J.Phys. Chem. B, 111 (22): 6151-6155, 2007
[1] Bing Yuan, Li-LiXing, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Self-assembly ofhighly oriented lamellar nanoparticle-phospholipid nanocomposites on solidsurfaces”, J. Am. Chem. Soc., 129 (37): 11332, 2007
专利《温敏性杂化颗粒药物载体及其制备方法和应用》，201510989352.9
专利《氧化石墨烯/溶菌酶抗菌纳米复合薄膜材料、其制备方法及作为抗菌材料的应用》，CN102165963A
专利《透射电子显微镜样品支撑膜和透射电子显微镜样品的制作方法》，CN102142348A
欢迎物理、化学、生物等相关专业的学生报考。
元冰，苏州大学软凝聚态物理及交叉研究中心，教授，博士生导师。2004年本科毕业于山东大学，2009年于中科院物理研究所获理学博士学位，后于南京大学、新加坡国立大学、美国斯坦福大学分别进行了为期1-2年的博士后（访问）研究。主要从事细胞膜界面动力学及功能纳米复合材料相关的研究工作。在生物膜与纳米材料（蛋白质、多肽）的界面相互作用研究、以天然抗菌肽为基础的新型抗菌药物设计等领域取得了一系列创新性成果。目前的主要研究兴趣包括：(1) 细胞膜界面动力学；(2)多肽类抗耐药菌药物设计；（3）有机/无机功能纳米复合材料。具体涉及细胞内吞、多肽抗菌、药物可控搭载与释放等。
【开授课程】
普通物理（三）
普通物理-电磁学（英文，承担1/2）
仰望星空（承担1/2）
软物质物理（研究生课程，合上）
【课题组小照】
主要从事细胞膜界面动力学及功能纳米复合材料相关的研究工作。先后在J. Am. Chem. Soc.等杂志上发表论文70余篇。主持（包括结题）国家自然科学基金三项、江苏省自然科学基金两项、中国博士后科学基金两项。目前的主要研究兴趣包括：(1) 细胞膜与生物大分子的界面相互作用；(2)多肽类抗耐药菌药物设计；(3)有机/无机功能纳米复合材料。具体涉及细胞内吞、多肽抗菌、药物可控搭载与释放等。
【近期主要研究方向】
1.（以天然多肽为基础的）抗耐药菌药物设计
A molecular architectural design that promises potent antimicrobial activity against multidrug-resistant pathogens, NPG Asia Mater., 13, 18, 2021.
Designing Melittin-Graphene Hybrid Complexes for Enhanced Antibacterial Activity, Adv. Healthc. Mater., 1801521, 2019.
Graphene oxide as antibacterial sensitizer: mechanically disturbed cell membrane for enhanced poration efficiency of melittin, Carbon, 149, 248-256, 2019.
2.纳米药物的细胞内化机制及生物毒性：新设备开发&单分子研究
Photo-Voltage Transients for Real-Time Analysis of the Interactions between Molecules and Membranes, ACS Appl. Bio Mater., 4(1), 620-629, 2021.
Membrane perturbation of fullerene and graphene oxide distinguished by pore-forming peptide melittin,Carbon, 180, 67-76, 2021.
Correlation between single-molecule dynamics and biological functions of antimicrobial peptide melittin, J. Phys. Chem. Lett., 11, 4834-4841, 2020.
Cardiolipin Selectively Binds to the Interface of VsSemiSWEET and Regulates Its Dimerization, J. Phys. Chem. Lett., 12, 1940-1946, 2021.
Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model, Small, 12(9), 1140-1146, 2016.
3.（生物膜）功能纳米复合材料
Modulated enhancement in ion transport through carbon nanotubes by lipid decoration, Carbon, 111, 459-466, 2017.
Modulated deformation of lipid membrane to vesicles and tubes due to reduction of graphene oxide substrate under laser irradiation, Carbon, 98, 300-306, 2016.
Self-assembly of highly oriented lamellar nanoparticle-phospholipid nanocomposites on solid surfaces, J. Am. Chem. Soc., 129 (37): 11332, 2007.
【部分论文列表】
[68] Kejie He†, Yushuang Wei†, Zhihong Zhang, Haibo Chen, Bing Yuan*, Hong-Bo Pang* and Kai Yang*, Membrane-curvature-mediated co-endocytosis of bystander and functional nanoparticles, Nanoscale, 2021, in press.
[67] Che Zhang,† Yuke Ge,† Xuemei Lu,† Zhonglan Chen,† Jiaojiao Liu, Mengling Zhang, Kai Yang,* Bing Yuan*, Membrane perturbation of fullerene and graphene oxide distinguished by pore-forming peptide melittin, Carbon, 180, 67-76, 2021.
[66] Zhihong Zhang, Wendong Ma, Kejie He, Bing Yuan* and Kai Yang*, Ligand-Decoration Determines the Translational and Rotational Dynamics of Nanoparticles on a Lipid Bilayer Membrane, Phys. Chem. Chem. Phys., 23, 9158-9165, 2021.
[65] Zhonglan Chen#, Xuemei Lu#, Jiaojiao Liu#, Xiaodong Tian, Wenwen Li, Kai Yang*, Bing Yuan*, Lipid Phase Influences the Dynamic Interactions between Graphene Oxide Nanosheets and a Phospholipid Membrane, J. Phys. Chem. B, 125, 14, 3589–3597, 2021.
[64] Bing Yuan, Jiaojiao Liu, Zhixiong Deng, Lin Wei, Wenwen Li, Yujiang Dou, Zhonglan Chen, Che Zhang, Yu Xia, Mengling Zhang, Kai Yang*, Yuqiang Ma*, Zhenhui Kang*, Designed molecular architecture promises potent antimicrobial activity against multidrug-resistant pathogens, NPG Asia Mater., 13, 18, 2021.
[63] Zhixiong Deng, Bing Yuan*, Kai Yang*, Cardiolipin Selectively Binds to the Interface of VsSemiSWEET and Regulates Its Dimerization, J. Phys. Chem. Lett., 12, 1940-1946, 2021.
[62] Yujiang Dou#, Wenwen Li#, Yu Xia#, Zhonglan Chen, Zhenyu Wu, Yuke Ge, Zhao Lin, Mengling Zhang, Kai Yang, Bing Yuan*, Zhenhui Kang*, Photo-voltage transients for real-time analysis of the interactions between molecules and membranes, ACS Appl. Bio Mater., 4(1), 620-629, 2021.
[61] Jia Li, Xuemei Lu, Wendong Ma, Zhonglan Chen, Shuqing Sun, Qinghui Wang, Bing Yuan*, Kai Yang*, Cholesterols work as a molecular regulator of the antimicrobial peptide-membrane interactions, Front. Mol. Biosci., 8:638988. doi: 10.3389/fmolb.2021.638988, 2021.
[60] Wenwen Li#, Zhao Lin#, Bing Yuan*, Kai Yang*, Tail-Structure Regulated Phase Behaviors of a Lipid Bilayer, Chinese Phys. B, 29(12), 128701, 2020.
[59] 鲍美美, 杨恺*, 元冰*, Influenza virus and coronavirus: cellular binding and internalization. Acta Phys. Sin., 69(20), 208701, 2020. 流感病毒和冠状病毒的细胞表面结合与内化, 物理学报 (Review)
[58] Wendong Ma, Shuqing Sun, Wenwen Li, Zhihong Zhang, Zhao Lin, Yu Xia, Bing Yuan* and Kai Yang*, Individual Roles of Peptides PGLa and Magainin 2 in Synergistic Membrane Poration, Langmuir, 36, 26, 7190-7199, 2020.
[57] Cheng Xu#, Wendong Ma#, Kang Wang, Kejie He, Zhonglan Chen, Jiaojiao Liu, Kai Yang* and Bing Yuan*, Correlation between single-molecule dynamics and biological functions of antimicrobial peptide melittin, J. Phys. Chem. Lett., 11, 4834-4841, 2020.
[56] Xu Cheng, Lin Zhao, Yang Kai* and Yuan Bing*, Single molecular kinetics during the interactions between melittin and a bi-component lipid membrane, Acta Phys. Sin., 69(10), 108701, 2020.
[55] Zhixiong Deng, Xuemei Lu, Cheng Xu, Bing Yuan* and Kai Yang*, Lipid-Specific Interactions Determine the Organization and Dynamics of Membrane-Active Peptide Melittin, Soft Matter, 16, 3498-3504, 2020.
[54] Jiajia Hong, Xuemei Lu, Zhixiong Deng, Shufeng Xiao, Bing Yuan*, Kai Yang*, How Melittin Inserts into Cell Membrane: Conformational Changes, Inter-Peptide Cooperation, and Disturbance on the Membrane, Molecules 24(9), 1775, 2019. (Review)
[53] Zhixiong Deng, Jingliang Li, Bing Yuan*, Kai Yang*, Residue-specialized Membrane Poration Kinetics of Melittin and Its Variants: Insight from Mechanistic Landscapes, Commun. Theor. Phys.71, 887-902, 2019.
[52] Shufeng Xiao#, Xuemei Lu#, Lu Gou#, Jingliang Li, Yuqiang Ma, Jiaojiao Liu*, Kai Yang*, Bing Yuan*，Graphene oxide as antibacterial sensitizer: mechanically disturbed cell membrane for enhanced poration efficiency of melittin, Carbon, 149, 248-256, 2019.
[50] Kai Yang, Ran Yang, Xiaodong Tian, Kejie He, Seth Leon Filbrun, Ning Fang, Yu-qiang Ma, Bing Yuan*, Partitioning of nanoscale particles on a heterogeneous multicomponent lipid bilayer, Phys. Chem. Chem. Phys., 20, 28241-28248, 2018.
[49] Jiaojiao Liu, Shufeng Xiao, Jingliang Li, Bing Yuan*, Kai Yang*, Yuqiang Ma, Molecular details on the intermediate states of melittin action on a cell membrane, BBA-Biomembranes, 1860, 2234-2241, 2018.
[48] Jiaojiao Liu#, Bin Song#, Jingliang Li, Xiaodong Tian, Yuqiang Ma, Kai Yang*, Bing Yuan*, Photoluminescence modulation of silicon nanoparticles via highly ordered arrangement with phospholipid membranes, Colloids and Surfaces B: Biointerfaces, 170, 656-662, 2018.
[47] Wenbin Wang, Ran Yang, Fei Zhang, Bing Yuan*, Kai Yang*, Yuqiang Ma, Partner-facilitating transmembrane penetration of nanoparticles: a biological test in Silico, Nanoscale, 10, 11670-11678, 2018.
[46] Jing-Yu Chen, Zahra Komeily-Nia, Lin-Peng Fan, Zhen-Yu Li, Bing Yuan, Bin Tang, Jing-Liang Li*, Manipulating the fractal fiber network of a molecular gel with surfactants, Journal of Colloid and Interface Science, 526, 356–365, 2018.
[45] Jiaojiao Liu#, Qi Chang#, Meimei Bao, Bing Yuan*, Kai Yang*, Yuqiang Ma, “Silicon Quantum Dots Delivered Phthalocyanine for Fluorescence Guided Photodynamic Therapy of Tumor”, Chin. Phys. B, 26(9), 098102, 2017.
[44] Zahra Komeily Nia, Jingyu Chen, Bing Yuan, Bin Tang, Jingliang Li*, “Optimizing the free radical content of graphene oxide by controlling its reduction”, Carbon, 116, 703-712, 2017.
[43] Jiaojiao Liu, Rui Wang, Sicong Wu, Bing Yuan*, Meimei Bao, Jingliang Li, Yujiang Dou, Yao He* and Kai Yang*, “One-pot synthesis of silicon based nanoparticles with incorporated phthalocyanine for long-term bioimaging and photo-dynamic therapy of tumors”, Nanotechnology, 28(13), 135601, 2017.
[42] Ye Li, Bing Yuan, Kai Yang, Xianren Zhang, Bing Yan, Dapeng Cao*, Counterintuitive Cooperative Endocytosis of like-charged Nanoparticles in Cellular Internalization: Computer Simulation and Experiment, Nanotechnology, DOI: 10.1088/1361-6528/aa56e0, 2017.
[41] Bing Yuan*, Xiangxu Jiang, Chu Yao, Meimei Bao, Jiaojiao Liu, Yujiang Dou, Yinze Xu, Yao He*, Kai Yang*, Yuqiang Ma, “Plasmon-enhanced fluorescence imaging with silicon-based silver chips for protein and nucleic acid assay”, Anal. Chim. Acta, 955, 98-107, 2017.
[40] Jiaojiao Liu#, Xiaodong Tian#, Meimei Bao, Jingliang Li, Yujiang Dou, Bing Yuan*, Kai Yang*, Yuqiang Ma, Manipulation of cellular orientation and migration by internalized magnetic particles, Mater. Chem. Front., DOI: 10.1039/c6qm00219f, 2017.
[39] Xue-mei Lu, Bing Yuan*, Xian-ren Zhang, Kai Yang*, and Yu-qiang Ma, “Molecular modeling of transmembrane delivery of paclitaxel by shock waves with nanobubbles”, Appl. Phys. Lett., 110, 023701, 2017. (封面文章)
[38] Jiaojiao Liu, Bing Yuan*, Xuewu Wu, Jingliang Li, Fangming Han, Yujiang Dou, Muzi Chen, Zhaohui Yang*, Kai Yang*, and Yuqiang Ma, “Modulated enhancement in ion transport through carbon nanotubes by lipid decoration”, Carbon, 111, 459-466, 2017.
[37] Jing-Yu Chen, Bing Yuan, Zhen-Yu Li, Bin Tang, Akhil Gupta, Sheshanath-Vishwanath Bhosale, Jing-Liang Li*, “Synergistic coassembly of two structurally different molecular gelators”, Langmuir, 32, 12175–12183, 2016.
[36] Jingyu Chen, Bing Yuan, Zhenyu Li, Bin Tang, Elizabeth Ankers, Xungai Wang, Jing Liang Li, “Controlling the supramolecular architecture of molecular gels with surfactants”, Langmuir, 32 (4), 1171–1177, 2016.
[35] Byumseok Koh, Xiaoyang Li, Bo Zhang, Bing Yuan, Yi Lin, Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, Yongye Liang, and Hongjie Dai*, “Visible to Near-Infrared Fluorescence Enhanced Cellular Imaging on Plasmonic Gold Chips”, Small, 12(4), 457-465, 2016.
[34] Jiaojiao Liu, Meimei Bao, Jingliang Li, YuyanWeng, Yujiang Dou, Bing Yuan*, Kai Yang, Yuqiang Ma*, “Modulated Deformation of Lipid Membrane to Vesicles and Tubes due to Reduction of Graphene Oxide Substrate under Laser Irradiation”, Carbon, 98, 300-306, 2016.
[33] Qiuju Ji#, Bing Yuan#, Xuemei Lu, Kai Yang*, and Yuqiang Ma*, Controlling the Nanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: A Computational Model, Small, 12(9), 1140-1146, 2016. (封面文章)
[32] Hao Yang, Ling Wang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Adhesion of an Ultrasmall Nanoparticle on a Bilayer Membrane is Still Size and Shape Dependent, J. Mater. Sci. Technol., 31, 660-663, 2015.
[31] Haizhen Zhang, Qiuju Ji, Changjin Huang, Sulin Zhang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Cooperative Transmembrane Penetration of Nanoparticles, Sci. Rep., 5, 10525, 2015.
[30] Fan Xu, Meimei Bao, Longfei Rui, Jiaojiao Liu, Jingliang Li, Yujiang Dou, Kai Yang, Bing Yuan*, and Yuqiang Ma*, Self-assembly of Monolayered Lipid Membranes for Surface coating of a Nanoconfined Bombyx Mori Silk Fibroin Film, RSC Advances, 5, 65684-65689, 2015.
[29] Longfei Rui, Jiaojiao Liu, Jingliang Li, Yuyan Weng, Yujiang Dou, Bing Yuan*, Kai Yang, Yuqiang Ma*, Reduced Graphene Oxide Directed Self-Assembly of Phospholipid Monolayers in Liquid and Gel Phases, BBA – Biomembranes, 1848, 1203-1211, 2015
[28] Haizhen Zhang, Ling Wang, Bing Yuan, Kai Yang*, Yuqiang Ma, “Effect of receptor structure and length on the wrapping of a nanoparticle by a lipid membrane”, Materials, 7(5), 3855-3866, 2014
[27] Jiaojiao Liu, Jingliang Li, Zexin Zhang, Yuyan Weng, Gaojian Chen, Bing Yuan*, Kai Yang and Yuqiang Ma*, Encapsulation of Hydrophobic Phthalocyanine with Poly(N-isopropylacrylamide)/Lipid Composite Microspheres for Thermo-Responsive Release and Photodynamic Therapy, Materials, 7(5), 3481-3493, 2014
[26] Naiyan Lu, Jiaojiao Liu, Jingliang Li, Zexin Zhang, Yuyan Weng, Bing Yuan*, Kai Yang and Yuqiang Ma*, Tunable Dual-stimuli Response of a Microgel Composite Consisting of Reduced Graphene Oxide Nanoparticles and Poly(N-isopropylacrylamide) Hydrogel Microsphere, J. Mater. Chem. B, 2(24), 3791-3798, 2014
[25] Yu Liu, Rong-Yao Wang*, Jing-Liang Li, Bing Yuan, Min Han, Peng Wang, Xiang-Yang Liu, Identify Kinetic Features of Fibers Growing, Branching, and Bundling in Microstructure Engineering of Crystalline Fiber Network, Crys. Eng. Comm., 16, 5402-5408, 2014
[24] Yujiang Dou, Jingliang Li, Bing Yuan*, Kai Yang*, Lipid Merging, Protrusion and Vesicle Release Triggered by Shrinking/swelling of Poly(N-isopropylacrylamide) Microgel Particles, Appl. Surf. Sci., 296, 95-99, 2014
[23] Jingliang Li, Bin Tang, Bing Yuan, Lu Sun, Xungai Wang*, A review of optical imaging and therapy using nanosized graphene and graphene oxide, Biomaterials, 34, 9519-9534, 2013
[22] Naiyan Lu, Bing Yuan*, Kai Yang*, Nonspecific adsorption of charged mesoporous nanoparticles on supported thiol/lipid hybrid bilayers, Acta Phys. Sin., 62(17), 178701, 2013
[21] Naiyan Lu, Kai Yang; Jingliang Li; Yuyan Weng, Bing Yuan*, Yuqiang Ma*, Controlled Drug Loading and Release of a Stimuli-responsive Lipogel Consisting of Poly(N-isopropylacrylamide) Particle and Lipids,J. Phys. Chem. B, 117, 9677-9682, 2013
[20] Kai Yang, Bing Yuan*, Yuqiang Ma*, Influence of geometric nanoparticle’s rotation on cellular internalization Process, Nanoscale, 5, 7998-8006, 2013
[19] Jiaojiao Liu, Naiyan Lu, Jingliang Li, Yuyan Weng, Bing Yuan*, Kai Yang*,Yuqiang Ma, Influence of Surface Chemistry on Particle Internalization into Giant Unilamellar Vesicles, Langmuir, 29(25), 8039-8045, 2013
[18] Nai-Yan Lu; Kai Yang; Jing-Liang Li; Bing Yuan*; Yu-Qiang Ma*, Vesicle Deposition and Subsequent Membrane-melittin Interactions on Different Substrates: a QCM-D Experiment, BBA – Biomembranes, 1828(8), 1918-1925, 2013
[17] Rong-Yao Wang, Peng Wang, Jing-Liang Li, Bing Yuan, Yu Liu, Li Li, and Xiang-Yang Liu, From Kinetics-structure Analysis to Engineering Crystalline Fiber Network in Soft Materials, Phys. Chem. Chem. Phys., 15, 3313-3319, 2013
[16] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, Rong-Yao Wang, and Xun-Gai Wang, Control of crystallization in supramolecular soft materials engineering, Soft Matter, 9, 435-442, 2013
[15] Naiyan Lu, Kai Yang, Bing Yuan* and Yuqiang Ma*, Molecular Response and Cooperative Behavior during the Interactions of Melittin with a Membrane: Dissipative Quartz Crystal Microbalance Experiments and Simulations, J. Phys. Chem. B, 116, 9432-9438, 2012
[14] Kai Yang, Bing Yuan and Yuqiang Ma, “Curvature Changes of Bilayer Membranes Studied by Computer Simulations”,J. Phys. Chem. B, 116, 7196-7202, 2012
[13] Bing Yuan, Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma and Ying-Jun Wang, “Size invariance of fibrous networks of supramolecular soft materials during formation under critical volume confinement”, Soft Matter, 8(19), 5187-5193, 2012
[12] Tao Zhu, Fan Xu, Bing Yuan, Chunlai Ren, Zhongying Jiang and Yuqiang Ma, “Effect of calcium cation on lipid vesicle deposition on silicon dioxide surface under various thermal conditions”, Colloid Surface B, 89, 228-233, 2012
[11] Bing Yuan, Shu-Xin Hu, Nai-Yan Lu, Fan Xu, Kun Zhou, Yu-Qiang Ma, and Ming Li, “Electrical bistability in self-assembled hybrid multilayers of phospholipid and nanoparticles”,Nanotechnology, 22(31): 315303, 2011
[10] Bing Yuan*, Ze-Xin Zhang*, and Kun Zhou, “Graphene oxide monolayers as supporting films for high resolution transmission electron microscopy”,Appl. Surf. Sci., 257(13): 5754-5758, 2011
[9] Bing Yuan, Tao Zhu, Zexin Zhang, Zhongying Jiang, and Yuqiang Ma, “Self-assembly of multilayered functional films based on graphene oxide sheets for controlled release”,J. Mater. Chem., 21(10): 3471-3476, 2011
[8] Bing Yuan, Xiang-Yang Liu, Jing-Liang Li, and Hong-Yao Xu, “Volume Confinement Induced Microstructural Transition and Property Enhancement of Supramolecular Soft Materials”, Soft Matter, 7(5): 1708-1713, 2011
[7] Bing Yuan, Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma, and Hong-Yao Xu, “Critical behavior of confined supramolecular soft materials in microscopic scale”,Chem. Commun., 47(10): 2793-2795, 2011 (Hot article, and featured by the editor)
[6] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, and Rong-Yao Wang, “Kinetically controlled homogenization and transformation of crystalline fiber networks in supramolecular materials”, Crystal Growth & Design, 11(7), 3227-3234, 2011
[5] Jing-Liang Li, Bing Yuan, Xiang-Yang Liu, and Hong-Yao Xu, “Microengineering of Supramolecular Soft Materials by Design of the Crystalline Fiber Networks”, Crystal Growth & Design, 10(6), 2699-2706, 2010
[4] Yu-Dong Zhang, Shu-Xin Hu, Bing Yuan, Xi-Miao Hou, Ying Lu, and Ming Li, “Subnanometer-Thick PbS Film on Organic Substrate and Its Usage as Buffer for Homo- and Heteroepitaxial Overgrowth”, Langmuir, 25(10), 5609-5613, 2009
[3] Li-Li Xing, Bing Yuan, Shu-Xin Hu, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Electrochemical Synthesis of Highly Oriented Layered Zinc Hydroxide with Intercalated p-Aminobenzoic Acid”, J. Phys. Chem. C, 112(10), 3800-3804, 2008
[2] Bing Yuan, Li-Li Xing, Yu-Dong Zhang, Ying Lu, Yi-Yong Luo, Zhen-Hong Mai, and Ming Li, “Penetration and saturation of lysozyme in phospholipid bilayers”, J. Phys. Chem. B, 111 (22): 6151-6155, 2007
[1] Bing Yuan, Li-Li Xing, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Self-assembly of highly oriented lamellar nanoparticle-phospholipid nanocomposites on solid surfaces”, J. Am. Chem. Soc., 129 (37): 11332, 2007
【专利】
[6]《一种采用抗菌肽和富勒烯联合抗菌方法》，申请号/专利号：202010131067.4，申请日：2020.02.28
[5]《一种基于抗菌肽和亲水聚合物的抗菌药物及制备方法》，申请号/专利号：202010129914.3，申请日：2020.02.28
[4]《一种抗菌肽复合材料及其制备方法与应用》，申请号/专利号：2018110620367，申请日：2018.09.12
[3]《温敏性杂化颗粒药物载体及其制备方法和应用》，申请（专利）号201510989352.9，申请日2015.12.25
[2]《透射电子显微镜样品支撑膜和透射电子显微镜样品的制作方法》，申请（专利）号201110040813.X，申请日2011.02.18
[1]《氧化石墨烯/溶菌酶抗菌纳米复合薄膜材料、其制备方法及作为抗菌材料的应用》，申请（专利）号ZL201010610000.5，申请日2010.12.29
1. 生物膜与界面
1) 生物膜在固体表面的自组装及响应重组
2) 纳米颗粒的跨膜内吞
3) 生物膜与蛋白质的界面相互作用：抗菌肽的分子作用机制及微结构设计
2. 功能纳米复合材料
1) 纳米颗粒的长程有序排布及性质调制
2) 智能杂化材料的可控释放
3) 药物搭载与肿瘤治疗
3. 细胞行为调控
图例：
1. 生物膜与界面
1) 生物膜在固体表面的自组装及响应重组
Carbon,98, 300-306, 2016
Appl. Surf.Sci., 296, 95-99, 2014
Carbon,111, 459-466, 2017
2) 纳米颗粒的跨膜内吞
Langmuir,29(25), 8039-8045, 2013
Sci.Rep., 5, 10525, 2015
Small,12(9), 1140-1146, 2016 (封面文章)
Appl.Phys. Lett., 110, 023701, 2017 (封面文章)
3) 生物膜与蛋白质的界面相互作用：抗菌肽的分子作用机制及微结构设计
2. 功能纳米复合材料
1) 纳米颗粒的长程有序排布
J. Am.Chem. Soc., 129 (37): 11332, 2007
Nanotechnology, 22(31), 315303, 2011
2) 智能杂化材料的可控释放
J. Mater. Chem., 21(10), 3471-3476, 2011
J. Mater.Chem. B, 2(24), 3791-3798, 2014
3) 药物搭载与肿瘤治疗
Nanotechnology, 28(13),135601, 2017
3. 细胞行为调控
Mater.Chem. Front., DOI:10.1039/c6qm00219f, 2017
与杨恺教授合作，构建了以“实验与模拟相结合”为特色的研究队伍。
王瑞（硕士）毕业留影，2017
刘娇娇（博士）毕业答辩, 2017
卢雪梅（硕士）毕业留影，2017
普通物理（三）
普通物理-电磁学（英文，承担1/2）
仰望星空（承担1/2）
软物质物理（研究生课程，合上）
【本科生项目】
2019年省级大学生创新创业训练计划项目（陆琰洲，周珂儿，刘之恒）
2019年科学前沿创新实践I（马宗光）
2018年莙政基金项目（鞠煜）
2017年江苏省高校第十四届大学生物理及实验科技作品创新竞赛（常琪；一等奖）
2016年校级大学生创新创业训练计划项目（常琪，燕婧文，徐可；优秀等级）
2013年省级大学生创新创业训练计划项目（张燕南等；2/2）
[50]Kai Yang, Ran Yang, Xiaodong Tian, Kejie He, Seth Leon Filbrun, Ning Fang,Yu-qiang Ma, Bing Yuan*,Partitioning of nanoscale particles on a heterogeneous multicomponent lipidbilayer, Physical Chemistry Chemical Physics, 20, 28241-28248, 2018.
[49] Jiaojiao Liu, ShufengXiao, Jingliang Li, Bing Yuan*, KaiYang*, Yuqiang Ma, Molecular details on the intermediate states of melittinaction on a cell membrane, BBA-Biomembranes, 1860, 2234-2241, 2018.
[48] Jiaojiao Liu#, BinSong#, Jingliang Li, Xiaodong Tian, Yuqiang Ma, Kai Yang*, Bing Yuan*, Photoluminescence modulation of silicon nanoparticlesvia highly ordered arrangement with phospholipid membranes, Colloidsand Surfaces B: Biointerfaces, 170, 656-662, 2018.
[47] Wenbin Wang, Ran Yang,Fei Zhang, Bing Yuan*, Kai Yang*,Yuqiang Ma, Partner-facilitating transmembrane penetration of nanoparticles: abiological test in Silico, Nanoscale, 10, 11670-11678, 2018.
[46] Jing-Yu Chen, ZahraKomeily-Nia, Lin-Peng Fan, Zhen-Yu Li, BingYuan, Bin Tang, Jing-Liang Li*, Manipulating the fractal fiber network of amolecular gel with surfactants, Journalof Colloid and Interface Science, 526, 356–365, 2018.
[45] Jiaojiao Liu#, QiChang#, Meimei Bao, Bing Yuan*, KaiYang*, Yuqiang Ma, “Silicon Quantum Dots Delivered Phthalocyanine forFluorescence Guided Photodynamic Therapy of Tumor”, Chin. Phys. B, 26(9),098102, 2017.
[44] Zahra Komeily Nia,Jingyu Chen, Bing Yuan, Bin Tang,Jingliang Li*, “Optimizing the free radical content of graphene oxide bycontrolling its reduction”, Carbon, 116, 703-712, 2017.
[43] Jiaojiao Liu, RuiWang, Sicong Wu, Bing Yuan*, MeimeiBao, Jingliang Li, Yujiang Dou, Yao He* and Kai Yang*, “One-pot synthesis ofsilicon based nanoparticles with incorporated phthalocyanine for long-termbioimaging and photo-dynamic therapy of tumors”, Nanotechnology, 28(13),135601, 2017.
[42] Ye Li, Bing Yuan, Kai Yang, Xianren Zhang,Bing Yan, Dapeng Cao*, Counterintuitive Cooperative Endocytosis of like-chargedNanoparticles in Cellular Internalization: Computer Simulation and Experiment, Nanotechnology, DOI:10.1088/1361-6528/aa56e0, 2017.
[41] Bing Yuan*, Xiangxu Jiang, Chu Yao, Meimei Bao, Jiaojiao Liu,Yujiang Dou, Yinze Xu, Yao He*, Kai Yang*, Yuqiang Ma, “Plasmon-enhancedfluorescence imaging with silicon-based silver chips for protein and nucleicacid assay”, Anal. Chim. Acta, 955, 98-107, 2017.
[40] Jiaojiao Liu#,Xiaodong Tian#, Meimei Bao, Jingliang Li, Yujiang Dou, Bing Yuan*, Kai Yang*, Yuqiang Ma, Manipulation of cellular orientation andmigration by internalized magnetic particles, Mater.Chem. Front., DOI: 10.1039/c6qm00219f, 2017.
[39] Xue-mei Lu, Bing Yuan*, Xian-ren Zhang, Kai Yang*,and Yu-qiang Ma, “Molecular modeling of transmembrane delivery of paclitaxel byshock waves with nanobubbles”, Appl. Phys. Lett., 110, 023701, 2017.(封面文章)
[38] Jiaojiao Liu, Bing Yuan*, Xuewu Wu, Jingliang Li, FangmingHan, Yujiang Dou, Muzi Chen, Zhaohui Yang*, Kai Yang*, and Yuqiang Ma,“Modulated enhancement in ion transport through carbon nanotubes by lipiddecoration”, Carbon, 111, 459-466, 2017.
[37] Jing-Yu Chen, Bing Yuan, Zhen-Yu Li, Bin Tang, AkhilGupta, Sheshanath-Vishwanath Bhosale, Jing-Liang Li*, “Synergistic coassemblyof two structurally different molecular gelators”, Langmuir, 32,12175–12183, 2016.
[36] Jingyu Chen, Bing Yuan, Zhenyu Li, Bin Tang,Elizabeth Ankers, Xungai Wang, Jing Liang Li, “Controlling the supramoleculararchitecture of molecular gels with surfactants”, Langmuir, 32 (4),1171–1177, 2016.
[35] Byumseok Koh, XiaoyangLi, Bo Zhang, Bing Yuan, Yi Lin,Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, YongyeLiang, and Hongjie Dai*, “Visible to Near-Infrared Fluorescence EnhancedCellular Imaging on Plasmonic Gold Chips”, Small, 12(4), 457-465, 2016.
[34] Jiaojiao Liu, MeimeiBao, Jingliang Li, YuyanWeng, Yujiang Dou, Bing Yuan*, Kai Yang, YuqiangMa*, “Modulated Deformation of Lipid Membrane to Vesicles and Tubes due toReduction of Graphene Oxide Substrate under Laser Irradiation”, Carbon,98, 300-306, 2016.
[33] Qiuju Ji#, BingYuan#, Xuemei Lu, Kai Yang*, and Yuqiang Ma*, Controlling theNanoscale Rotational Behaviors of Nanoparticles on the Cell Membranes: AComputational Model, Small, 12(9), 1140-1146, 2016. (封面文章)
[32] Hao Yang, Ling Wang, Bing Yuan, Kai Yang*, and Yuqiang Ma*, Adhesionof an Ultrasmall Nanoparticle on a Bilayer Membrane is Still Size and ShapeDependent, J. Mater. Sci. Technol., 31, 660-663, 2015.
[31] Haizhen Zhang, QiujuJi, Changjin Huang, Sulin Zhang, BingYuan, Kai Yang*, and Yuqiang Ma*, Cooperative Transmembrane Penetration ofNanoparticles, Sci. Rep., 5, 10525, 2015.
[30] Fan Xu, Meimei Bao,Longfei Rui, Jiaojiao Liu, Jingliang Li, Yujiang Dou, Kai Yang, Bing Yuan*,and Yuqiang Ma*, Self-assembly of Monolayered Lipid Membranes for Surfacecoating of a Nanoconfined Bombyx Mori Silk Fibroin Film, RSC Advances,5, 65684-65689, 2015.
[29] Longfei Rui, JiaojiaoLiu, Jingliang Li, Yuyan Weng, Yujiang Dou, Bing Yuan*, Kai Yang,Yuqiang Ma*, Reduced Graphene Oxide Directed Self-Assembly of PhospholipidMonolayers in Liquid and Gel Phases, BBA – Biomembranes, 1848,1203-1211, 2015
[28] Haizhen Zhang, LingWang, Bing Yuan, Kai Yang*, YuqiangMa, “Effect of receptor structure and length on the wrapping of a nanoparticleby a lipid membrane”, Materials, 7(5), 3855-3866, 2014
[27] Jiaojiao Liu,Jingliang Li, Zexin Zhang, Yuyan Weng, Gaojian Chen, Bing Yuan*, KaiYang and Yuqiang Ma*, Encapsulation of Hydrophobic Phthalocyanine withPoly(N-isopropylacrylamide)/Lipid Composite Microspheres for Thermo-ResponsiveRelease and Photodynamic Therapy, Materials, 7(5), 3481-3493,2014
[26] Naiyan Lu, JiaojiaoLiu, Jingliang Li, Zexin Zhang, Yuyan Weng, Bing Yuan*, Kai Yang andYuqiang Ma*, Tunable Dual-stimuli Response of a Microgel Composite Consistingof Reduced Graphene Oxide Nanoparticles and Poly(N-isopropylacrylamide)Hydrogel Microsphere, J. Mater. Chem. B, 2(24), 3791-3798, 2014
[25] Yu Liu, Rong-YaoWang*, Jing-Liang Li, BingYuan, Min Han, Peng Wang, Xiang-Yang Liu, Identify KineticFeatures of Fibers Growing, Branching, and Bundling in MicrostructureEngineering of Crystalline Fiber Network, Crys. Eng. Comm., 16, 5402-5408, 2014
[24] Yujiang Dou, JingliangLi, Bing Yuan*, Kai Yang*, Lipid Merging, Protrusion and Vesicle Release Triggered byShrinking/swelling of Poly(N-isopropylacrylamide) Microgel Particles, Appl. Surf. Sci.,296, 95-99, 2014
[23] Jingliang Li, BinTang, Bing Yuan,Lu Sun, Xungai Wang*, A review of optical imaging and therapy using nanosizedgraphene and graphene oxide, Biomaterials,34, 9519-9534, 2013
[22] Naiyan Lu, Bing Yuan*, Kai Yang*,Nonspecific adsorption of charged mesoporous nanoparticles on supportedthiol/lipid hybrid bilayers, ActaPhys. Sin., 62(17), 178701, 2013
[21] Naiyan Lu, Kai Yang;Jingliang Li; Yuyan Weng, Bing Yuan*, Yuqiang Ma*, Controlled DrugLoading and Release of a Stimuli-responsive Lipogel Consisting ofPoly(N-isopropylacrylamide) Particle and Lipids,J. Phys. Chem. B,117, 9677-9682, 2013
[20] Kai Yang, Bing Yuan*,Yuqiang Ma*, Influence of geometric nanoparticle’s rotation on cellularinternalization Process, Nanoscale, 5, 7998-8006, 2013
[19] Jiaojiao Liu, NaiyanLu, Jingliang Li, Yuyan Weng, Bing Yuan*, Kai Yang*,YuqiangMa, Influence of Surface Chemistry on Particle Internalization into GiantUnilamellar Vesicles, Langmuir, 29(25), 8039-8045, 2013
[18] Nai-Yan Lu; Kai Yang;Jing-Liang Li; Bing Yuan*; Yu-Qiang Ma*, Vesicle Deposition andSubsequent Membrane-melittin Interactions on Different Substrates: a QCM-DExperiment, BBA – Biomembranes, 1828(8), 1918-1925, 2013
[17] Rong-Yao Wang, PengWang, Jing-Liang Li, Bing Yuan, Yu Liu, Li Li, and Xiang-Yang Liu, FromKinetics-structure Analysis to Engineering Crystalline Fiber Network in SoftMaterials, Phys. Chem. Chem. Phys., 15, 3313-3319, 2013
[16] Jing-Liang Li, BingYuan, Xiang-Yang Liu, Rong-Yao Wang, and Xun-Gai Wang, Control ofcrystallization in supramolecular soft materials engineering, Soft Matter,9, 435-442, 2013
[15] Naiyan Lu, Kai Yang, BingYuan* and Yuqiang Ma*, Molecular Response and Cooperative Behavior duringthe Interactions of Melittin with a Membrane: Dissipative Quartz CrystalMicrobalance Experiments and Simulations, J. Phys. Chem. B, 116,9432-9438, 2012
[14] Kai Yang, Bing Yuan and Yuqiang Ma, “Curvature Changes of Bilayer Membranes Studied by ComputerSimulations”,J. Phys. Chem. B, 116, 7196-7202, 2012
[13] Bing Yuan,Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma and Ying-Jun Wang, “Size invarianceof fibrous networks of supramolecular soft materials during formation undercritical volume confinement”, Soft Matter, 8(19), 5187-5193, 2012
[12] Tao Zhu, Fan Xu, BingYuan, Chunlai Ren, Zhongying Jiang and Yuqiang Ma, “Effect of calciumcation on lipid vesicle deposition on silicon dioxide surface under variousthermal conditions”, Colloid Surface B, 89, 228-233, 2012
[11] Bing Yuan,Shu-Xin Hu, Nai-Yan Lu, Fan Xu, Kun Zhou, Yu-Qiang Ma, and Ming Li, “Electricalbistability in self-assembled hybrid multilayers of phospholipid andnanoparticles”,Nanotechnology, 22(31): 315303, 2011
[10] Bing Yuan*,Ze-Xin Zhang*, and Kun Zhou, “Graphene oxide monolayers as supporting films forhigh resolution transmission electron microscopy”,Appl. Surf. Sci.,257(13): 5754-5758, 2011
[9] Bing Yuan, TaoZhu, Zexin Zhang, Zhongying Jiang, and Yuqiang Ma, “Self-assembly ofmultilayered functional films based on graphene oxide sheets for controlledrelease”,J. Mater. Chem., 21(10): 3471-3476, 2011
[8] Bing Yuan,Xiang-Yang Liu, Jing-Liang Li, and Hong-Yao Xu, “Volume Confinement InducedMicrostructural Transition and Property Enhancement of Supramolecular SoftMaterials”, Soft Matter, 7(5): 1708-1713, 2011
[7] Bing Yuan,Jing-Liang Li, Xiang-Yang Liu, Yu-Qiang Ma, and Hong-Yao Xu, “Critical behaviorof confined supramolecular soft materials in microscopic scale”,Chem.Commun., 47(10): 2793-2795, 2011 (Hot article, and featured by theeditor)
[6] Jing-Liang Li, BingYuan, Xiang-Yang Liu, and Rong-Yao Wang, “Kinetically controlledhomogenization and transformation of crystalline fiber networks insupramolecular materials”, Crystal Growth & Design, 11(7),3227-3234, 2011
[5] Jing-Liang Li, BingYuan, Xiang-Yang Liu, and Hong-Yao Xu, “Microengineering of SupramolecularSoft Materials by Design of the Crystalline Fiber Networks”, CrystalGrowth & Design, 10(6), 2699-2706, 2010
[4] Yu-Dong Zhang, Shu-XinHu, Bing Yuan, Xi-Miao Hou, Ying Lu, and Ming Li, “Subnanometer-ThickPbS Film on Organic Substrate and Its Usage as Buffer for Homo- andHeteroepitaxial Overgrowth”, Langmuir, 25(10), 5609-5613, 2009
[3] Li-Li Xing, BingYuan, Shu-Xin Hu, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li,“Electrochemical Synthesis of Highly Oriented Layered Zinc Hydroxide withIntercalated p-Aminobenzoic Acid”, J. Phys. Chem. C, 112(10),3800-3804, 2008
[2] Bing Yuan, Li-LiXing, Yu-Dong Zhang, Ying Lu, Yi-Yong Luo, Zhen-Hong Mai, and Ming Li,“Penetration and saturation of lysozyme in phospholipid bilayers”, J.Phys. Chem. B, 111 (22): 6151-6155, 2007
[1] Bing Yuan, Li-LiXing, Yu-Dong Zhang, Ying Lu, Zhen-Hong Mai, and Ming Li, “Self-assembly ofhighly oriented lamellar nanoparticle-phospholipid nanocomposites on solidsurfaces”, J. Am. Chem. Soc., 129 (37): 11332, 2007
专利《温敏性杂化颗粒药物载体及其制备方法和应用》，201510989352.9
专利《氧化石墨烯/溶菌酶抗菌纳米复合薄膜材料、其制备方法及作为抗菌材料的应用》，CN102165963A
专利《透射电子显微镜样品支撑膜和透射电子显微镜样品的制作方法》，CN102142348A
欢迎物理、化学、生物等相关专业的学生报考。