苏州大学材料与化学化工学部、软凝聚态物理及交叉研究中心研究员,博士生导师,中国化学会高级会员,英国皇家化学会会士,胶体与界面B:生物界面杂志(Colloids and Surfaces B: Biointerfaces)的编辑。本科和硕士毕业于苏州大学,博士毕业于英国华威大学。其后在澳大利亚新南威尔士大学和香港中文大学从事博士后研究工作。曾获Overseas Research Scholarships Award、Warwick Postgraduate Research Fellowship、Macro Group Prize、ARC APD Fellowship等奖项,回国后获得教育部留学回国人员科研启动基金资助,主持国家自然科学基金面上项目及参与国家自然科学基金重点项目等多个高分子合成及应用相关课题。目前已发表论文百余篇,受邀在Wiley、Springer等出版的4本专著中撰写章节。在全国高分子学术论文报告会、美国化学会(ACS)、英国皇家化学会(RSC)、日本高分子学会(SPSJ)、日本糖生物学与糖工程学协会(JCGG)等重要国际会议多次做特邀报告。目前主要研究领域包括含糖聚合物、表界面聚合改性以及功能性高分子材料的合成制备。
Gaojian Chen is a Professor at Soochow University, a Fellow of the Royal Society of Chemistry, an editor of Colloids and Surfaces B: Biointerfaces. He received his PhD from the University of Warwick and has held postdoctoral positions at the University of New South Wales and the Chinese University of Hong Kong. His research focuses on the design and synthesis of novel bio-materials, with a particular emphasis on surface modification, cell interactions, and carbohydrate-based materials.
代表性论文:
研究论文
Selected articles
1. Zhang, H., Heng, X., Yang, H., Rao, Y., Yao, L., Zhu, Z., Chen, G., Chen, H. (2024). Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro-Adjuvants for Dendritic Cell Vaccine. Angewandte Chemie International Edition, 63(24), e202402853.
2. Guo, J., Wang, S., Yu, Z., Heng, X., Zhou, N., Chen, G. (2024). Well-Defined Oligo(azobenzene- graft -mannose): Photostimuli Supramolecular Self-Assembly and Immune Effect Regulation. ACS Macro Letters, 13(3), 273–279.
3. Yang, H., Yao, L., Wang, Y., Chen, G., Chen, H. (2023). Advancing cell surface modification in mammalian cells with synthetic molecules. Chemical Science, 14(46), 13325–13345.
4. Heng, X., Feng, R., Zhu, L., Yu, L., Chen, G., Chen, H. (2022). Dendritic cells maturation facilitated by group-adjustable lipopolysaccharide analogues synthesized via RAFT polymerization. Chinese Chemical Letters, 33(9), 4331–4334.
5. Yu, L., Feng, R., Zhu, L., Hao, Q., Chu, J., Gu, Y., Luo, Y., Zhang, Z., Chen, G., Chen, H. (2020). Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions. Science Advances, 6(47), eabb6595.
6. Luo, Y., Gu, Y., Feng, R., Brash, J., Eissa, A. M., Haddleton, D. M., Chen, G., Chen, H. (2019). Synthesis of glycopolymers with specificity for bacterial strains via bacteria-guided polymerization. Chemical Science, 10(20), 5251–5257.
专著章节
Book chapters
1. Feng, K., Hu, J., & Chen, G. (2021).Surface Immobilized Glycopolymers. In J. Barchi (Ed.), Comprehensive Glycoscience (2nd ed., 346–369). Elsevier.
2. Zhang, W., Chen, K. & Chen, G. (2016) Thiol-Based “Click” Chemistry for Macromolecular Architecture Design, in S. Chandrasekaran (Ed.), Click Reactions in Organic Synthesis (255-285). Wiley-VCH.
3. Li, X., Zhang, W., & Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry. In X. L. Sun (Ed.), Macro-Glycoligands. Methods in Molecular Biology (149–155). Springer.
4. Zhao, Y., Chen, G. & Chen G. (2015). Self-Assembly of Glycopolymers: From Nano-Objects to Hydrogels. In C. R. Becer & L. Hartmann (Ed.), Glycopolymer Code: Synthesis of Glycopolymers and their Applications (178-195). The Royal Society of Chemistry.
5. Pearson, S., Chen, G., & Stenzel, M. H. (2011). Synthesis of Glycopolymers. In R. Narain (Ed.), Engineered Carbohydrate-Based Materials for Biomedical Applications (1–118). John Wiley & Sons.
研究方向主要围绕生物大分子的合成与含糖聚合物材料的制备和应用。
包括:
生物大分子合成方法学
绿色可见光控制聚合
含糖材料制备及特异性识别
识别和靶向癌细胞的功能材料
识别和调控细菌/细胞的功能高分子
细胞表面糖基化工程
含糖聚合物
糖是自然界中许多天然产物的组成单元,是生物中常见的能量来源,也是很重要的一种多价态配体。糖与凝集素蛋白的特异性结合是包括细胞识别、病原体感染、细胞附着和分化等许多生命过程的基础。本研究立足于含糖聚合物材料的合成、与蛋白及细胞的作用以及应用拓展。
含糖聚合物合成
含糖聚合物,尤其是侧链含糖的聚合物,具有糖簇效应,常常被用来研究生物体间的相互作用或者进行疾病治疗。通过合成方法改进,我们能便利的合成一系列不同的含糖聚合物,并且结合实验和模拟比较不同含糖聚合物与凝集素蛋白的相互作用。
代表论文:
1) Macromolecules, 2014, 47(14), 4676–4683.
2) Polym. Chem., 2016, 7(25), 4263–4271..
3) Chem. Sci. 2019, 10(20), 5251–5257.
4) ACS Macro Lett. 2019, 8, 326-330.
5) ACS Macro Lett. 2024, 13, 273-279.

含糖聚合物功能表面
通过将具有适当物理和化学性能的聚合物薄层接枝到表面能够实现表面性能的优化。由于糖的生物相容性和特异性等独特性质,将糖聚物固定在表面上是研究细胞、细菌和生物材料之间识别和粘附的良好平台,有助于更好地理解生命中的关键过程,具有广阔的应用潜力。
代表论文:
1)Mater. Horizons, 2014, 1, 540-545.
2) Nanoscale, 2017, 9, 19263-19270.
3) ACS App. Mater. Inter., 2020, 12(24), 27632–27639.
4) Angewandte Chemie Int. Ed., 2024, e202402853.

含糖聚合物与细胞表面工程
细胞之间的相互作用对于从干细胞分化到免疫增强的各种应用至关重要。相互作用的调节可以通过设计细胞膜表面的成分来实现,这有助于理解生物过程并产生所需的生物功能。通过为细胞表面工程设计合适的含糖聚合物,我们可以实现特定的相互作用并成功调节细胞行为。我们还证明了糖-单体-适配聚合(S-MAP)方法可用于合成具有高特异性的糖聚合物,以更精确的方式识别和调节靶细胞。
代表论文:
1) ACS App. Mater. Inter.2017, 9(13), 11518–11527.
2) ACS Macro Lett.2019, 8(4), 337–344.
3) Sci. Adv.2020, 6(47), eabb6595.
4) Chem. Sci.2019, 10(20), 5251–5257.
5) Chem. Sci.2023, 14(46), 13325-13345.

本科教学
《生命中的甜蜜化学》
《材料化学 Materials Chemistry》
《科学讲座》
研究生教学
《学科交叉及前沿》
2024
Zhang, H., Heng, X., Yang, H., Rao, Y., Yao, L., Zhu, Z., Chen, G., & Chen, H. (2024). Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro‐Adjuvants for Dendritic Cell Vaccine. Angewandte Chemie International Edition. 63(24), e202402853. link

Guo, J., Wang, S., Yu, Z., Heng, X., Zhou, N., & Chen, G. (2024). Well-Defined Oligo(azobenzene- graft -mannose): Photostimuli Supramolecular Self-Assembly and Immune Effect Regulation. ACS Macro Letters, 13(3), 273–279. link

Zhao, J., Rao, Y., Zhang, H., Zhu, Z., Yao, L., Chen, G., & Chen, H. (2024). In situ PET-RAFT polymerization to prepare guanidine-and-carbohydrate modified ZnO nanoparticles. Polymer Chemistry, 15(21), 2140–2147. link
Published as part of the themed collection: Polymer Chemistry 15th Anniversary Collection

Hu, J., Guo, J., Zhao, J., Chen, Z., Kalulu, M., Chen, G., & Fu, G. (2024). Multifunctional, Degradable Wearable Sensors Prepared with an Initiator and Crosslinker-Free Method. ACS Applied Materials & Interfaces, 16(8), 10671–10681. link

Dai, A., Wang, W., Heng, X., Shu, W., Lu, S., Xu, Y., Wang, D., Pan, X., Li, N., Chen, G., & Zhu, J. (2024). High-Efficiency Bactericidal and Biofilm Elimination Ability of the Biodegradable Alternating Sequence Main-Chain Polyselenium Salt. ACS Applied Polymer Materials, 6(9), 4975–4984. link

Duan, Y., Ma, X., Guo, J., Shan, F., Pan, Y., Chen, Y., Chen, H., & Chen, G. (2024). Fe 0 -MAP Prepared Glycosurfaces for Selective Cell Capture: From Adherent to Suspended Cells. ACS Applied Materials & Interfaces, 16, 54943–54950. link
Published as part of the special issue:
“Celebrating the 110th Anniversary of the College of Chemistry, Chemical Engineering, and Materials Science of Soochow University”.

Zhu, Z., Heng, X., Shan, F., Yang, H., Wang, Y., Zhang, H., Chen, G., & Chen, H. (2024). Customizable Glycopolymers as Adjuvants for Cancer Immunotherapy: From Branching Degree Optimization to Cell Surface Engineering. Biomacromolecules, 25(12), 7975–7984. https://doi.org/10.1021/acs.biomac.4c01230

2023
Yang, H., Yao, L., Wang, Y., Chen, G., & Chen, H. (2023). Advancing cell surface modification in mammalian cells with synthetic molecules. Chemical Science, 14(46), 13325–13345. link


Heng, X., Shan, F., Yang, H., Hu, J., Feng, R., Tian, W., Chen, G., & Chen, H. (2023). Glycopolymers With On/Off Anchors: Confinement Effect on Regulating Dendritic Cells. Advanced Healthcare Materials, 12(28). link

Mei, R., Heng, X., Liu, X., & Chen, G. (2023). Glycopolymers for Antibacterial and Antiviral Applications. Molecules, 28(3), 985. link
Ma, X., Luo, Y., Zhang, P., Hu, J., Chen, G., & Chen, H. (2023). Surface-Initiated Synthesis of Cell-Specific Glycopolymers Using Live Mammalian Cells as Templates. Macromolecular Rapid Communications, 44(7),e202200881. link

2022

Heng, X., Feng, R., Zhu, L., Yu, L., Chen, G., & Chen, H. (2022). Dendritic cells maturation facilitated by group-adjustable lipopolysaccharide analogues synthesized via RAFT polymerization. Chinese Chemical Letters, 33(9), 4331–4334. link

Li, Y., Ma, X., Zhang, J., Pan, X., Li, N., Chen, G., & Zhu, J. (2022). Degradable Selenium-Containing Polymers for Low Cytotoxic Antibacterial Materials. ACS Macro Letters, 11(12), 1349–1354. link

Zhou, Y., Gu, C., Zheng, L., Shan, F., & Chen, G. (2022). Aqueous broadband photopolymerization on microreactor arrays: from high throughput polymerization to fabricating artificial cells. Polymer Chemistry, 13(7), 989–996. link

Hu, J., Lu, K., Gu, C., Heng, X., Shan, F., & Chen, G. (2022). Synthetic Sugar-Only Polymers with Double-Shoulder Task: Bioactivity and Imaging. Biomacromolecules, 23(3), 1075–1082. link

Gu, C., Shan, F., Zheng, L., Zhou, Y., Hu, J., & Chen, G. (2022). Towards a protein-selective Raman enhancement by a glycopolymer-based composite surface. Journal of Materials Chemistry. B, 10(9), 1434–1441. link

Zhu, L., Feng, R., Chen, G., Wang, C., Liu, Z., Zhang, Z., & Chen, H. (2022). Glycopolymer Engineering of the Cell Surface Changes the Single Cell Migratory Direction and Inhibits the Collective Migration of Cancer Cells. ACS Applied Materials and Interfaces, 14(4),4921-4930. link
2021
Xu, F., Jing, W., Chen, G., & Zhang, Z. (2021). Polymerization in Shear Flow: From Bowl-Shaped Glyco-Microcarriers to Self-Propelled Micromotors. ACS Macro Letters, 10(1), 9–13. link

Feng, R., Zhu, L., Heng, X., Chen, G., & Chen, H. (2021). Immune Effect Regulated by the Chain Length: Interaction between Immune Cell Surface Receptors and Synthetic Glycopolymers. ACS Applied Materials & Interfaces, 13(31), 36859–36867. link

Wang, J.-H., Chen, R., Zhao, Z.-Q., Shen, J., Yang, H., Luo, Y., Chen, G.-J., Chen, H., & Brash, J. L. (2021). Feasible Fabrication of Hollow Micro-vesicles by Non-amphiphilic Macromolecules Based on Interfacial Cononsolvency. Chinese Journal of Polymer Science (English Edition), 39(7),856-8644. link
2020
Feng, K., Peng, L., Yu, L., Zheng, Y., Chen, R., Zhang, W., Chen, G. (2020). Universal Antifogging and Antimicrobial Thin Coating Based on Dopamine-Containing Glycopolymers. ACS Applied Materials & Interfaces, 12(24), 27632–27639. link

Wang, J., Liu, Y., Li, X., Luo, Y., Zheng, L., Hu, J., Chen, G., Chen, H. (2020). Ultralow Crosslinked Microgel Brings Ultrahigh Catalytic Efficiency. Macromolecular Rapid Communications, 41(13), 2000135. link

Yu, L., Feng, R., Zhu, L., Hao, Q., Chu, J., Gu, Y., Luo, Y.,Zhang, Z.,Chen, G., Chen, H. (2020). Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions. Science Advances, 6(47), eabb6595. link

Zheng, L., Luo, Y., Chen, K., Zhang, Z., Chen, G. (2020). Highly Branched Gradient Glycopolymer: Enzyme-Assisted Synthesis and Enhanced Bacteria-Binding Ability. Biomacromolecules, 21(12), 5233–5240. link

Hu, J., Gu, Y., Liu, M., Zhang, W., Chen, H., Chen, G. (2020). Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes. Chemical Communications, 56(74), 10887–10889. link

2019
Zheng, Y., Luo, Y., Feng, K., Zhang, W., Chen, G. (2019). High Throughput Screening of Glycopolymers: Balance between Cytotoxicity and Antibacterial Property. ACS Macro Letters, 8(3), 326–330. link

Liu, Q., Jiang, S., Liu, B., Yu, Y., Zhao, Z.-A., Wang, C., Liu, Z.,Chen, G., Chen, H. (2019). Take Immune Cells Back on Track: Glycopolymer-Engineered Tumor Cells for Triggering Immune Response. ACS Macro Letters, 8(4), 337–344. link

Luo, Y., Gu, Y., Feng, R., Brash, J., Eissa, A. M., Haddleton, D. M., Chen, G., Chen, H. (2019). Synthesis of glycopolymers with specificity for bacterial strains via bacteria-guided polymerization. Chemical Science, 10(20), 5251–5257. link
(2019 Chemical Science HOT Article Collection)

Gu, Y., Liu, B., Liu, Q., Hang, Y., Wang, L., Brash, J. L., Chen, G., Chen, H. (2019). Modular Polymers as a Platform for Cell Surface Engineering: Promoting Neural Differentiation and Enhancing the Immune Response. ACS Applied Materials & Interfaces, 11(51), 47720–47729. link

Wang, J., Liu, Y., Chen, R., Zhang, Z., Chen, G., Chen, H. (2019). Ultralow Self-Cross-Linked Poly( N -isopropylacrylamide) Microgels Prepared by Solvent Exchange. Langmuir, 35(43), 13991–13998. link

2018
Peng, L., Luo, Y., Zheng, Y., Zhang, W., & Chen, G. (2018). Sunlight-Induced RAFT Synthesis of Multifaceted Glycopolymers with Surface Anchoring, In Situ AgNP Formation, and Antibacterial Properties. ACS Applied Nano Materials, 1(5), 2219–2226. http://doi.org/10.1021/acsanm.8b00286
Wen, M., Liu, M., Xue, W., Yang, K., Chen, G., & Zhang, W. (2018). Simple and Green Strategy for the Synthesis of “Pathogen-Mimetic” Glycoadjuvant@AuNPs by Combination of Photoinduced RAFT and Bioinspired Dopamine Chemistry. ACS Macro Letters, 7(1), 70–74. http://doi.org/10.1021/acsmacrolett.7b00837
2017
Weng, Y., Li, Z., Peng, L., Zhang, W., & Chen, G. (2017). Fabrication of carbon quantum dots with nano-defined position and pattern in one step via sugar-electron-beam writing. Nanoscale, 9(48), 19263–19270. http://doi.org/10.1039/C7NR07892G
Hu, X., Gao, J., Luo, Y., Wei, T., Dong, Y., Chen, G., & Chen, H. (2017). One-Pot Multicomponent Synthesis of Glycopolymers through a Combination of Host-Guest Interaction, Thiol-ene, and Copper-Catalyzed Click Reaction in Water. Macromolecular Rapid Communications, 38(20), 1700434. http://doi.org/10.1002/marc.201700434
Peng, L., Zhou, S., Yang, B., Bao, M., Chen, G., & Zhang, X. (2017). Chemically Modified Surface Having a Dual-Structured Hierarchical Topography for Controlled Cell Growth. ACS Applied Materials & Interfaces, 9(28), 24339–24347. http://doi.org/10.1021/acsami.7b06197
Xue, W., Wang, J., Wen,M., Chen, G., & Zhang, W. (2017). Integration of CuAAC Polymerization andControlled Radical Polymerization into Electron Transfer Mediated“Click-Radical” Concurrent Polymerization. Macromolecular Rapid Communications, 38(6), 1600733.http://doi.org/10.1002/marc.201600733
Liu, Q., Lyu, Z., Yu,Y., Zhao, Z., Hu, S., Yuan, L., Chen, G., Chen, H. (2017). Synthetic Glycopolymers forHighly Efficient Differentiation of Embryonic Stem Cells into Neurons: Lipo- orNot? ACS Applied Materials & Interfaces, 9(13), 11518–11527.http://doi.org/10.1021/acsami.7b01397
Peng, L., Li, Z., Li,X., Xue, H., Zhang, W., & Chen, G. (2017). Integrating Sugar and Dopamineinto One Polymer: Controlled Synthesis and Robust Surface Modification. Macromolecular Rapid Communications, 38(3), 1600548.http://doi.org/10.1002/marc.201600548
Xue, H., Peng, L.,Dong, Y., Zheng, Y., Luan, Y., Hu, X., Chen, G., Chen, H. (2017). Synthesis ofstar-glycopolymers by Cu(0)-mediated radical polymerisation in the absence andpresence of oxygen. RSC Adv., 7(14), 8484–8490.http://doi.org/10.1039/C6RA28763H
2016
Liu, Q., Xue, H., Gao,J., Cao, L., Chen, G., & Chen, H. (2016). Synthesis of lipo-glycopolymersfor cell surface engineering. Polym. Chem., 7(47), 7287–7294.http://doi.org/10.1039/C6PY01788F
Wang, J., Rivero, M.,Mu?oz Bonilla, A., Sanchez-Marcos, J., Xue, W., Chen, G., … Zhu, X. (2016).Natural RAFT Polymerization: Recyclable-Catalyst-Aided, Opened-to-Air, andSunlight-Photolyzed RAFT Polymerizations. ACS Macro Letters, 5,1278–1282. http://doi.org/10.1021/acsmacrolett.6b00818
Li, Z., Zhang, P., Lu,W., Peng, L., Zhao, Y., & Chen, G. (2016). Ratiometric Fluorescent pHProbes Based on Glycopolymers. Macromolecular Rapid Communications, 37(18),1513–1519. http://doi.org/10.1002/marc.201600242
Xue, L., Xiong, X.,Chen, K., Luan, Y., Chen, G., & Chen, H. (2016). Modular synthesis ofglycopolymers with well-defined sugar units in the side chain via Ugi reactionand click chemistry: hetero vs. homo. Polym. Chem., 7(25),4263–4271. http://doi.org/10.1039/C6PY00734A
Cao, L., Shi, X., Cui,Y., Yang, W., Chen, G., Yuan, L., & Chen, H. (2016). Protein–polymerconjugates prepared via host–guest interactions: effects of the conjugationsite, polymer type and molecular weight on protein activity. Polym. Chem., 7(32), 5139–5146. http://doi.org/10.1039/C6PY00882H
Wang, J., Wang, X.,Xue, W., Chen, G., Zhang, W., & Zhu, X. (2016). Initiator andPhotocatalyst-Free Visible Light Induced One-Pot Reaction: Concurrent RAFTPolymerization and CuAAC Click Reaction. Macromolecular Rapid Communications, 37(9), 799–804. http://doi.org/10.1002/marc.201600004
Chen, K., Bao, M.,Mu?oz Bonilla, A., Zhang, W., & Chen, G. (2016). A biomimicking andelectrostatic self-assembly strategy for the preparation of glycopolymerdecorated photoactive nanoparticles. Polym. Chem., 7(14),2565–2572. http://doi.org/10.1039/C6PY00129G
Li, X., Zhang, W.,& Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-DecoratedNanoparticles: Combing Thiol-ene with Catecholic Chemistry (Vol. 1367, pp.149–155). Springer. http://doi.org/10.1007/978-1-4939-3130-9_12
2015
Wang, S., Yuan, F.,Chen, K., Chen, G., Tu, K., Wang, H., & Wang, L.-Q. (2015). Synthesis ofHemoglobin Conjugated Polymeric Micelle: A ZnPc Carrier with OxygenSelf-Compensating Ability for Photodynamic Therapy. Biomacromolecules, 16(9),2693–2700. http://doi.org/10.1021/acs.biomac.5b00571
Shi, X., Zhan, W.,Chen, G., Yu, Q., Liu, Q., Du, H., … Chen, H. (2015). Regulation of ProteinBinding Capability of Surfaces via Host–Guest Interactions: Effects ofLocalized and Average Ligand Density. Langmuir, 31(22),6172–6178. http://doi.org/10.1021/acs.langmuir.5b01380
Yuan, F., Wang, S., Lu,W., Chen, G., Tu, K., Jiang, H., & Wang, L.-Q. (2015). Facile preparationof cancer-specific polyelectrolyte nanogels from natural and synthetic sugar polymers. J. Mater. Chem. B, 3(22), 4546–4554.http://doi.org/10.1039/C5TB00539F
Li, B., Wang, M., Chen,K., Cheng, Z., Chen, G., & Zhang, Z. (2015). Synthesis of BiofunctionalJanus Particles. Macromolecular Rapid Communications, 36(12),1200–1204. http://doi.org/10.1002/marc.201500063
Li, X., & Chen, G.(2015). Glycopolymer-based nanoparticles: synthesis and application. Polym.Chem., 6(9), 1417–1430. http://doi.org/10.1039/C4PY01740D
Xue, L., Lyu, Z., Luan,Y., Xiong, X., Pan, J., Chen, G., & Chen, H. (2015). Efficient cancer cellcapturing SiNWAs prepared via surface-initiated SET-LRP and click chemistry. Polym.Chem., 6(19), 3708–3715. http://doi.org/10.1039/C5PY00247H
2014
Li, X., Bao, M., Weng, Y., Yang, K., Zhang, W.*, & Chen, G.* (2014).Glycopolymer-coated iron oxide nanoparticles: shape-controlled synthesis andcellular uptake. Journal of Materials Chemistry B, 2(34), 5569.doi:10.1039/C4TB00852A
Li, X., Wang, L., Chen, G.*, Haddleton, D. M., & Chen, H.* (2014).Visible light induced fast synthesis of protein-polymer conjugates:controllable polymerization and protein activity. Chemical Communications, 50(49), 6506–8. doi:10.1039/c4cc02277g
Lu, J., Fu, C., Wang, S., Tao, L.*, Yan, L.*, Haddleton, D. M., Chen,G.*, Wei, Y. (2014). From Polymer Sequence Control to Protein Recognition:Synthesis, Self-Assembly and Lectin Binding. Macromolecules, 47(14),4676–4683. doi:10.1021/ma500664u
Lu, J., Zhang, W., Richards, S., Gibson, M. I., & Chen, G.* (2014).Glycopolymer-coated gold nanorods synthesised by a one pot copper(0) catalyzedtandem RAFT/click reaction. Polymer Chemistry, 5(7), 2326.doi:10.1039/c3py01526b
Lu, J., Zhang, W., Yuan, L., Ma, W., Li, X., Lu, W., Zhao, Y.*, Chen,G.* (2014). One-pot synthesis of glycopolymer-porphyrin conjugate as photosensitizerfor targeted cancer imaging and photodynamic therapy. Macromolecular Bioscience, 14(3), 340–6. doi:10.1002/mabi.201300451
Lu, W., Ma, W., Lu, J., Li, X., Zhao, Y.*, & Chen, G.* (2014).Microwave-assisted synthesis of glycopolymer-functionalized silvernanoclusters: combining the bioactivity of sugar with the fluorescence andcytotoxicity of silver. Macromolecular Rapid Communications, 35(8),827–33. doi:10.1002/marc.201300905
Shi, X., Chen, G.*, Yuan, L., Tang, Z., Liu, W., Zhang, Q.,Haddleton, D.*, Chen,H.* (2014). Integrating a thermoresponsive copolymer with host–guestinteractions for fabricating molecular recognition surfaces. Materials Horizons, 1(5), 540. doi:10.1039/C4MH00081A
Wang, J., Zhu, H., Chen, G., Hu, Z.*, Weng, Y., Wang, X., & Zhang, W.*(2014). Controlled synthesis and self-assembly of dopamine-containing copolymerfor honeycomb-like porous hybrid particles. Macromolecular Rapid Communications, 35(11), 1061–7. doi:10.1002/marc.201400029
Wang, L., Li, J., Zhang, W., Chen, G.*, Zhang, W.*, & Zhu, X. (2014).A novel approach to synthesize polymers for potential photodynamic therapy:from benzenedinitrile to phthalocyanine. Polymer Chemistry, 5(8),2872. doi:10.1039/c3py01129a
Xue, L., Lyu, Z., Shi, X., Tang, Z., Chen, G.*, & Chen, H.* (2014).Fast and Green Synthesis of a Smart Glyco-surface via Aqueous Single ElectronTransfer-Living Radical Polymerization. Macromolecular Chemistry and Physics, 215(15), 1491–1497. doi:10.1002/macp.201400227
Yuan, F., Wang, S., Chen, G.*, Tu, K., Jiang, H., & Wang, L.* (2014).Novel chitosan-based pH-sensitive and disintegrable polyelectrolyte nanogels. Colloidsand Surfaces. B, Biointerfaces, 122, 194–201.doi:10.1016/j.colsurfb.2014.06.042
Chen, G., Yang, J., Lu, G., Liu, P. C., Chen, Q., Xie, Z., & Wu, C.*(2014). One Stone Kills Three Birds: Novel Boron-Containing Vesicles forPotential BNCT, Controlled Drug Release, and Diagnostic Imaging. Molecular Pharmaceutics. doi:10.1021/mp400641u
Du, X., Wang, Y., Yuan, L.*, Weng, Y., Chen, G.*, & Hu, Z.* (2014).Guiding the behaviors of human umbilical vein endothelial cells with patternedsilk fibroin films. Colloids and Surfaces. B, Biointerfaces, 122,79–84. doi:10.1016/j.colsurfb.2014.06.049
Luo, F., Cheng, Z., Wang, M., Chen, G., & Zhang, Z.* (2014). Synthesisof soft colloids with well-controlled softness. Chemical Communications, 50(56), 7535–7. doi:10.1039/c4cc02485k
Liu, J., Li, J., Zhang, Z., Weng, Y., Chen, G., Yuan, B.*, … Ma, Y.*(2014). Encapsulation of Hydrophobic Phthalocyanine with Poly(N-isopropylacrylamide)/LipidComposite Microspheres for Thermo-Responsive Release and Photodynamic Therapy. Materials, 7(5), 3481–3493. doi:10.3390/ma7053481
Wang, Z., Chen, G., Lu, J., Hong, L.*, & Ngai, T.* (2013).Investigation of the factors affecting the carbohydrate–lectin interaction byITC and QCM-D. Colloid and Polymer Science, 292(2), 391–398.doi:10.1007/s00396-013-3080-0
Liu, X., Yuan, L., Li, D., Tang, Z., Wang, Y., Chen, G., Chen,H.*, Brash, J. L.* (2014). Blood compatible materials: state of the art. Journalof Materials Chemistry B, 2(35), 5718. doi:10.1039/C4TB00881B
Tan, M., Wang, H., Wang, Y., Chen, G., Yuan, L.*, & Chen, H.* (2014).Recyclable antibacterial material: silicon grafted with 3,6-O-sulfated chitosanand specifically bound by lysozyme. Journal of Materials Chemistry B, 2(5),569. doi:10.1039/c3tb21358g
2013
Li, J., Zhang, W., Hu, Z., Jiang, X.-J., Ngai, T., Lo, P.-C., Zhang,W., Chen, G.* (2013). Novel phthalocyanine and PEG-methacrylates basedtemperature-responsive polymers for targeted photodynamic therapy. Polymer Chemistry, 4(3), 782. doi:10.1039/c2py20668d
Shi, X., Chen, G.*, Wang, Y., Yuan, L., Zhang, Q., Haddleton, D. M., &Chen, H.* (2013). Control the wettability ofpoly(n-isopropylacrylamide-co-1-adamantan-1-ylmethyl acrylate) modifiedsurfaces: the more Ada, the bigger impact? Langmuir, 29(46), 14188–95.doi:10.1021/la4037748
2012
Shen, Q., Zhang, J., Zhang, S., Hao, Y., Zhang, W.*, Zhang, W., Chen, G.,Zhang, Z., Zhu, X.* (2012). Facile one-pot/one-step technique forpreparation of side-chain functionalized polymers: Combination of SET-RAFT polymerizationof azide vinyl monomer and click chemistry. Journal of Polymer Science PartA: Polymer Chemistry, 50(6), 1120–1126.
Zhang, W., Chen, G., Hu, Z., Zhang, W., Zhang, Z., & Zhu, X.* (2012).Precisely controlled copper(0)-catalyzed one-pot reaction: Concurrent livingradical polymerization and click chemistry. Journal of Polymer Science PartA: Polymer Chemistry, 50(17), 3656–3663.
2011
Huynh, V. T., Chen, G., Souza, P. De, & Stenzel, M. H.* (2011).Thiol-yne and Thiol-ene “Click” Chemistry as a Tool for a Variety of PlatinumDrug Delivery Carriers, from Statistical Copolymers to Crosslinked Micelles. Biomacromolecules, 12(5), 1738–51. doi:10.1021/bm200135e
Kumar, J., McDowall, L., Chen, G., & Stenzel, M. H.* (2011). Synthesisof thermo-responsive glycopolymers via copper catalysed azide–alkyne “click”chemistry for inhibition of ricin: the effect of spacer between polymerbackbone and galactose. Polymer Chemistry, 2(8), 1879–1886.doi:10.1039/c1py00048a
Pearson, S., Chen, G., & Stenzel, M. H.* (2011). Synthesis ofGlycopolymers. In R. Narain (Ed.), Engineered Carbohydrate-Based Materialsfor Biomedical Applications (pp. 1–118). John Wiley & Sons.doi:10.1002/9780470944349.ch1
Tao, L., Chen, G., Zhao, L., Xu, J., Huang, E., Liu, A., … Davis, T. P.* (2011).Protein release from biodegradable polyHPMA-lysozyme conjugates resulting inbioactivity enhancement. Chemistry, an Asian Journal, 6(6),1398–404. doi:10.1002/asia.201000729
Wang, J., Yue, Y., Chen, G., & Xia, J.* (2011). Protease-promoted drugdelivery using peptide-functionalized gold nanoparticles. Soft Matter, 7(16),7217. doi:10.1039/c1sm05242j
Zhang, W., Zhang, W., Cheng, Z., Zhou, N., Zhu, J., Zhang, Z., Chen,G., Zhu, X.* (2011). Synthesis and Aggregation Behaviors of NonlinearMultiresponsive, Multihydrophilic Block Copolymers. Macromolecules, 44(9),3366–3373. doi:10.1021/ma200083v
2010
Chen, Y., Chen, G., & Stenzel, M. H.* (2010). Synthesis and LectinRecognition of Glyco Star Polymers Prepared by “Clicking” Thiocarbohydratesonto a Reactive Scaffold. Macromolecules, 43(19), 8109–8114.doi:10.1021/ma100919x
Hetzer, M., Chen, G., Barner-Kowollik, C., & Stenzel, M. H.* (2010).Neoglycopolymers based on 4-vinyl-1,2,3-triazole monomers prepared by clickchemistry. Macromolecular Bioscience, 10(2), 119–26.doi:10.1002/mabi.200900199
Ting, S., Chen, G., & Stenzel, M. H.* (2010). Synthesis ofglycopolymers and their multivalent recognitions with lectins. Polymer Chemistry, 1(9), 1392. doi:10.1039/c0py00141d
before 2010
Chen, G., Amajjahe, S., & Stenzel, M. H. (2009). Synthesis ofthiol-linked neoglycopolymers and thermo-responsive glycomicelles as potentialdrug carrier. Chemical Communications, (10), 1198–200.doi:10.1039/b900215d
Chen, G., Kumar, J., Gregory, A., & Stenzel, M. H. (2009). Efficientsynthesis of dendrimers via a thiol-yne and esterification process and theirpotential application in the delivery of platinum anti-cancer drugs. Chemical Communications, 12(41), 6291–3. doi:10.1039/b910340f
Chen, G., Tao, L., Mantovani, G., Geng, J., Nystr?m, D., & Haddleton,D. M. (2007). A Modular Click Approach to Glycosylated Polymeric Beads: Design,Synthesis and Preliminary Lectin Recognition Studies. Macromolecules, 40(21),7513–7520. doi:10.1021/ma071362v
Chen, G., Tao, L., Mantovani, G., Ladmiral, V., Burt, D. P., Macpherson,J. V., & Haddleton, D. M. (2007). Synthesis of azide/alkyne-terminalpolymers and application for surface functionalisation through a [2 + 3]Huisgen cycloaddition process,??click chemistry? Soft Matter, 3(6),732. doi:10.1039/b618325e
Chen, G., Wright, P. M., Geng, J., Mantovani, G., & Haddleton, D. M.(2008). Tunable thermoresponsive water-dispersed multiwalled carbon nanotubes. Chemical Communications, (9), 1097–9. doi:10.1039/b718112d
Chen, G., Zhu, X., Zhu, J., & Cheng, Z. (2004). Plasma-InitiatedControlled/Living Radical Polymerization of Methyl Methacrylate in the Presenceof 2-Cyanoprop-2-yl 1-dithionaphthalate(CPDN). Macromolecular Rapid Communications, 25(7), 818–824. doi:10.1002/marc.200300266
Geng, J., Lindqvist, J., Mantovani, G., Chen, G., Sayers, C. T., Clarkson,G. J., & Haddleton, D. M. (2007). Well-Defined Poly(N-glycosyl1,2,3-triazole) Multivalent Ligands: Design, Synthesis and Lectin BindingStudies. QSAR & Combinatorial Science, 26(11-12), 1220–1228.doi:10.1002/qsar.200740089
Geng, J., Mantovani, G., Tao, L., Nicolas, J., Chen, G., Wallis, R., …Haddleton, D. M. (2007). Site-directed conjugation of “clicked” glycopolymersto form glycoprotein mimics: binding to mammalian lectin and induction ofimmunological function. Journal of the American Chemical Society, 129(49),15156–63. doi:10.1021/ja072999x
Gu, W., Chen, G., & Stenzel, M. H. (2009). Synthesis ofglyco-microspheres via a thiol-ene coupling reaction. Journal of Polymer Science Part A: Polymer Chemistry, 47(20), 5550–5556.doi:10.1002/pola.23615
McDowall, L., Chen, G., & Stenzel, M. H. (2008). Synthesis ofSeven-Arm Poly(vinyl pyrrolidone) Star Polymers with Lysozyme Core Prepared byMADIX/RAFT Polymerization. Macromolecular Rapid Communications, 29(20),1666–1671. doi:10.1002/marc.200800416
Tao, L., Chen, G., Mantovani, G., York, S., & Haddleton, D. M. (2006).Modification of multi-wall carbon nanotube surfaces with poly(amidoamine)dendrons: synthesis and metal templating. Chemical Communications, (47),4949–51. doi:10.1039/b609065f
Tao, L., Geng, J., Chen, G., Xu, Y., Ladmiral, V., Mantovani, G., &Haddleton, D. M. (2007). Bioconjugation of biotinylated PAMAM dendrons toavidin. Chemical Communications, (33), 3441–3. doi:10.1039/b709080c
Withey, A. B. J., Chen, G., Nguyen, T. L. U., & Stenzel, M. H. (2009).Macromolecular cobalt carbonyl complexes encapsulated in a click-cross-linkedmicelle structure as a nanoparticle to deliver cobalt pharmaceuticals. Biomacromolecules, 10(12), 3215–26. doi:10.1021/bm901050x
Xu, W., Zhu, X., Cheng, Z., Chen, G., & Zhu, J. (2005). Polymerizationof styrene with tetramethylthiuram disulfide as an initiator in the presence of2,2,6,6-tetramethyl-1-piperidinyloxy. Journal of Polymer Science Part A:Polymer Chemistry, 43(3), 543–551. doi:10.1002/pola.20533
本课题组现招收有志于科研工作的研究生及博士后。招生方向包括化学(高分子化学与物理、材料化学),材料科学与工程等,欢迎具有化学、材料背景的同学报考。
苏州大学材料与化学化工学部、软凝聚态物理及交叉研究中心研究员,博士生导师,中国化学会高级会员,英国皇家化学会会士,胶体与界面B:生物界面杂志(Colloids and Surfaces B: Biointerfaces)的编辑。本科和硕士毕业于苏州大学,博士毕业于英国华威大学。其后在澳大利亚新南威尔士大学和香港中文大学从事博士后研究工作。曾获Overseas Research Scholarships Award、Warwick Postgraduate Research Fellowship、Macro Group Prize、ARC APD Fellowship等奖项,回国后获得教育部留学回国人员科研启动基金资助,主持国家自然科学基金面上项目及参与国家自然科学基金重点项目等多个高分子合成及应用相关课题。目前已发表论文百余篇,受邀在Wiley、Springer等出版的4本专著中撰写章节。在全国高分子学术论文报告会、美国化学会(ACS)、英国皇家化学会(RSC)、日本高分子学会(SPSJ)、日本糖生物学与糖工程学协会(JCGG)等重要国际会议多次做特邀报告。目前主要研究领域包括含糖聚合物、表界面聚合改性以及功能性高分子材料的合成制备。
Gaojian Chen is a Professor at Soochow University, a Fellow of the Royal Society of Chemistry, an editor of Colloids and Surfaces B: Biointerfaces. He received his PhD from the University of Warwick and has held postdoctoral positions at the University of New South Wales and the Chinese University of Hong Kong. His research focuses on the design and synthesis of novel bio-materials, with a particular emphasis on surface modification, cell interactions, and carbohydrate-based materials.
代表性论文:
研究论文
Selected articles
1. Zhang, H., Heng, X., Yang, H., Rao, Y., Yao, L., Zhu, Z., Chen, G., Chen, H. (2024). Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro-Adjuvants for Dendritic Cell Vaccine. Angewandte Chemie International Edition, 63(24), e202402853.
2. Guo, J., Wang, S., Yu, Z., Heng, X., Zhou, N., Chen, G. (2024). Well-Defined Oligo(azobenzene- graft -mannose): Photostimuli Supramolecular Self-Assembly and Immune Effect Regulation. ACS Macro Letters, 13(3), 273–279.
3. Yang, H., Yao, L., Wang, Y., Chen, G., Chen, H. (2023). Advancing cell surface modification in mammalian cells with synthetic molecules. Chemical Science, 14(46), 13325–13345.
4. Heng, X., Feng, R., Zhu, L., Yu, L., Chen, G., Chen, H. (2022). Dendritic cells maturation facilitated by group-adjustable lipopolysaccharide analogues synthesized via RAFT polymerization. Chinese Chemical Letters, 33(9), 4331–4334.
5. Yu, L., Feng, R., Zhu, L., Hao, Q., Chu, J., Gu, Y., Luo, Y., Zhang, Z., Chen, G., Chen, H. (2020). Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions. Science Advances, 6(47), eabb6595.
6. Luo, Y., Gu, Y., Feng, R., Brash, J., Eissa, A. M., Haddleton, D. M., Chen, G., Chen, H. (2019). Synthesis of glycopolymers with specificity for bacterial strains via bacteria-guided polymerization. Chemical Science, 10(20), 5251–5257.
专著章节
Book chapters
1. Feng, K., Hu, J., & Chen, G. (2021).Surface Immobilized Glycopolymers. In J. Barchi (Ed.), Comprehensive Glycoscience (2nd ed., 346–369). Elsevier.
2. Zhang, W., Chen, K. & Chen, G. (2016) Thiol-Based “Click” Chemistry for Macromolecular Architecture Design, in S. Chandrasekaran (Ed.), Click Reactions in Organic Synthesis (255-285). Wiley-VCH.
3. Li, X., Zhang, W., & Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry. In X. L. Sun (Ed.), Macro-Glycoligands. Methods in Molecular Biology (149–155). Springer.
4. Zhao, Y., Chen, G. & Chen G. (2015). Self-Assembly of Glycopolymers: From Nano-Objects to Hydrogels. In C. R. Becer & L. Hartmann (Ed.), Glycopolymer Code: Synthesis of Glycopolymers and their Applications (178-195). The Royal Society of Chemistry.
5. Pearson, S., Chen, G., & Stenzel, M. H. (2011). Synthesis of Glycopolymers. In R. Narain (Ed.), Engineered Carbohydrate-Based Materials for Biomedical Applications (1–118). John Wiley & Sons.
研究方向主要围绕生物大分子的合成与含糖聚合物材料的制备和应用。
包括:
生物大分子合成方法学
绿色可见光控制聚合
含糖材料制备及特异性识别
识别和靶向癌细胞的功能材料
识别和调控细菌/细胞的功能高分子
细胞表面糖基化工程
含糖聚合物
糖是自然界中许多天然产物的组成单元,是生物中常见的能量来源,也是很重要的一种多价态配体。糖与凝集素蛋白的特异性结合是包括细胞识别、病原体感染、细胞附着和分化等许多生命过程的基础。本研究立足于含糖聚合物材料的合成、与蛋白及细胞的作用以及应用拓展。
含糖聚合物合成
含糖聚合物,尤其是侧链含糖的聚合物,具有糖簇效应,常常被用来研究生物体间的相互作用或者进行疾病治疗。通过合成方法改进,我们能便利的合成一系列不同的含糖聚合物,并且结合实验和模拟比较不同含糖聚合物与凝集素蛋白的相互作用。
代表论文:
1) Macromolecules, 2014, 47(14), 4676–4683.
2) Polym. Chem., 2016, 7(25), 4263–4271..
3) Chem. Sci. 2019, 10(20), 5251–5257.
4) ACS Macro Lett. 2019, 8, 326-330.
5) ACS Macro Lett. 2024, 13, 273-279.

含糖聚合物功能表面
通过将具有适当物理和化学性能的聚合物薄层接枝到表面能够实现表面性能的优化。由于糖的生物相容性和特异性等独特性质,将糖聚物固定在表面上是研究细胞、细菌和生物材料之间识别和粘附的良好平台,有助于更好地理解生命中的关键过程,具有广阔的应用潜力。
代表论文:
1)Mater. Horizons, 2014, 1, 540-545.
2) Nanoscale, 2017, 9, 19263-19270.
3) ACS App. Mater. Inter., 2020, 12(24), 27632–27639.
4) Angewandte Chemie Int. Ed., 2024, e202402853.

含糖聚合物与细胞表面工程
细胞之间的相互作用对于从干细胞分化到免疫增强的各种应用至关重要。相互作用的调节可以通过设计细胞膜表面的成分来实现,这有助于理解生物过程并产生所需的生物功能。通过为细胞表面工程设计合适的含糖聚合物,我们可以实现特定的相互作用并成功调节细胞行为。我们还证明了糖-单体-适配聚合(S-MAP)方法可用于合成具有高特异性的糖聚合物,以更精确的方式识别和调节靶细胞。
代表论文:
1) ACS App. Mater. Inter.2017, 9(13), 11518–11527.
2) ACS Macro Lett.2019, 8(4), 337–344.
3) Sci. Adv.2020, 6(47), eabb6595.
4) Chem. Sci.2019, 10(20), 5251–5257.
5) Chem. Sci.2023, 14(46), 13325-13345.

本科教学
《生命中的甜蜜化学》
《材料化学 Materials Chemistry》
《科学讲座》
研究生教学
《学科交叉及前沿》
2024
Zhang, H., Heng, X., Yang, H., Rao, Y., Yao, L., Zhu, Z., Chen, G., & Chen, H. (2024). Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro‐Adjuvants for Dendritic Cell Vaccine. Angewandte Chemie International Edition. 63(24), e202402853. link

Guo, J., Wang, S., Yu, Z., Heng, X., Zhou, N., & Chen, G. (2024). Well-Defined Oligo(azobenzene- graft -mannose): Photostimuli Supramolecular Self-Assembly and Immune Effect Regulation. ACS Macro Letters, 13(3), 273–279. link

Zhao, J., Rao, Y., Zhang, H., Zhu, Z., Yao, L., Chen, G., & Chen, H. (2024). In situ PET-RAFT polymerization to prepare guanidine-and-carbohydrate modified ZnO nanoparticles. Polymer Chemistry, 15(21), 2140–2147. link
Published as part of the themed collection: Polymer Chemistry 15th Anniversary Collection

Hu, J., Guo, J., Zhao, J., Chen, Z., Kalulu, M., Chen, G., & Fu, G. (2024). Multifunctional, Degradable Wearable Sensors Prepared with an Initiator and Crosslinker-Free Method. ACS Applied Materials & Interfaces, 16(8), 10671–10681. link

Dai, A., Wang, W., Heng, X., Shu, W., Lu, S., Xu, Y., Wang, D., Pan, X., Li, N., Chen, G., & Zhu, J. (2024). High-Efficiency Bactericidal and Biofilm Elimination Ability of the Biodegradable Alternating Sequence Main-Chain Polyselenium Salt. ACS Applied Polymer Materials, 6(9), 4975–4984. link

Duan, Y., Ma, X., Guo, J., Shan, F., Pan, Y., Chen, Y., Chen, H., & Chen, G. (2024). Fe 0 -MAP Prepared Glycosurfaces for Selective Cell Capture: From Adherent to Suspended Cells. ACS Applied Materials & Interfaces, 16, 54943–54950. link
Published as part of the special issue:
“Celebrating the 110th Anniversary of the College of Chemistry, Chemical Engineering, and Materials Science of Soochow University”.

Zhu, Z., Heng, X., Shan, F., Yang, H., Wang, Y., Zhang, H., Chen, G., & Chen, H. (2024). Customizable Glycopolymers as Adjuvants for Cancer Immunotherapy: From Branching Degree Optimization to Cell Surface Engineering. Biomacromolecules, 25(12), 7975–7984. https://doi.org/10.1021/acs.biomac.4c01230

2023
Yang, H., Yao, L., Wang, Y., Chen, G., & Chen, H. (2023). Advancing cell surface modification in mammalian cells with synthetic molecules. Chemical Science, 14(46), 13325–13345. link


Heng, X., Shan, F., Yang, H., Hu, J., Feng, R., Tian, W., Chen, G., & Chen, H. (2023). Glycopolymers With On/Off Anchors: Confinement Effect on Regulating Dendritic Cells. Advanced Healthcare Materials, 12(28). link

Mei, R., Heng, X., Liu, X., & Chen, G. (2023). Glycopolymers for Antibacterial and Antiviral Applications. Molecules, 28(3), 985. link
Ma, X., Luo, Y., Zhang, P., Hu, J., Chen, G., & Chen, H. (2023). Surface-Initiated Synthesis of Cell-Specific Glycopolymers Using Live Mammalian Cells as Templates. Macromolecular Rapid Communications, 44(7),e202200881. link

2022

Heng, X., Feng, R., Zhu, L., Yu, L., Chen, G., & Chen, H. (2022). Dendritic cells maturation facilitated by group-adjustable lipopolysaccharide analogues synthesized via RAFT polymerization. Chinese Chemical Letters, 33(9), 4331–4334. link

Li, Y., Ma, X., Zhang, J., Pan, X., Li, N., Chen, G., & Zhu, J. (2022). Degradable Selenium-Containing Polymers for Low Cytotoxic Antibacterial Materials. ACS Macro Letters, 11(12), 1349–1354. link

Zhou, Y., Gu, C., Zheng, L., Shan, F., & Chen, G. (2022). Aqueous broadband photopolymerization on microreactor arrays: from high throughput polymerization to fabricating artificial cells. Polymer Chemistry, 13(7), 989–996. link

Hu, J., Lu, K., Gu, C., Heng, X., Shan, F., & Chen, G. (2022). Synthetic Sugar-Only Polymers with Double-Shoulder Task: Bioactivity and Imaging. Biomacromolecules, 23(3), 1075–1082. link

Gu, C., Shan, F., Zheng, L., Zhou, Y., Hu, J., & Chen, G. (2022). Towards a protein-selective Raman enhancement by a glycopolymer-based composite surface. Journal of Materials Chemistry. B, 10(9), 1434–1441. link

Zhu, L., Feng, R., Chen, G., Wang, C., Liu, Z., Zhang, Z., & Chen, H. (2022). Glycopolymer Engineering of the Cell Surface Changes the Single Cell Migratory Direction and Inhibits the Collective Migration of Cancer Cells. ACS Applied Materials and Interfaces, 14(4),4921-4930. link
2021
Xu, F., Jing, W., Chen, G., & Zhang, Z. (2021). Polymerization in Shear Flow: From Bowl-Shaped Glyco-Microcarriers to Self-Propelled Micromotors. ACS Macro Letters, 10(1), 9–13. link

Feng, R., Zhu, L., Heng, X., Chen, G., & Chen, H. (2021). Immune Effect Regulated by the Chain Length: Interaction between Immune Cell Surface Receptors and Synthetic Glycopolymers. ACS Applied Materials & Interfaces, 13(31), 36859–36867. link

Wang, J.-H., Chen, R., Zhao, Z.-Q., Shen, J., Yang, H., Luo, Y., Chen, G.-J., Chen, H., & Brash, J. L. (2021). Feasible Fabrication of Hollow Micro-vesicles by Non-amphiphilic Macromolecules Based on Interfacial Cononsolvency. Chinese Journal of Polymer Science (English Edition), 39(7),856-8644. link
2020
Feng, K., Peng, L., Yu, L., Zheng, Y., Chen, R., Zhang, W., Chen, G. (2020). Universal Antifogging and Antimicrobial Thin Coating Based on Dopamine-Containing Glycopolymers. ACS Applied Materials & Interfaces, 12(24), 27632–27639. link

Wang, J., Liu, Y., Li, X., Luo, Y., Zheng, L., Hu, J., Chen, G., Chen, H. (2020). Ultralow Crosslinked Microgel Brings Ultrahigh Catalytic Efficiency. Macromolecular Rapid Communications, 41(13), 2000135. link

Yu, L., Feng, R., Zhu, L., Hao, Q., Chu, J., Gu, Y., Luo, Y.,Zhang, Z.,Chen, G., Chen, H. (2020). Promoting the activation of T cells with glycopolymer-modified dendritic cells by enhancing cell interactions. Science Advances, 6(47), eabb6595. link

Zheng, L., Luo, Y., Chen, K., Zhang, Z., Chen, G. (2020). Highly Branched Gradient Glycopolymer: Enzyme-Assisted Synthesis and Enhanced Bacteria-Binding Ability. Biomacromolecules, 21(12), 5233–5240. link

Hu, J., Gu, Y., Liu, M., Zhang, W., Chen, H., Chen, G. (2020). Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes. Chemical Communications, 56(74), 10887–10889. link

2019
Zheng, Y., Luo, Y., Feng, K., Zhang, W., Chen, G. (2019). High Throughput Screening of Glycopolymers: Balance between Cytotoxicity and Antibacterial Property. ACS Macro Letters, 8(3), 326–330. link

Liu, Q., Jiang, S., Liu, B., Yu, Y., Zhao, Z.-A., Wang, C., Liu, Z.,Chen, G., Chen, H. (2019). Take Immune Cells Back on Track: Glycopolymer-Engineered Tumor Cells for Triggering Immune Response. ACS Macro Letters, 8(4), 337–344. link

Luo, Y., Gu, Y., Feng, R., Brash, J., Eissa, A. M., Haddleton, D. M., Chen, G., Chen, H. (2019). Synthesis of glycopolymers with specificity for bacterial strains via bacteria-guided polymerization. Chemical Science, 10(20), 5251–5257. link
(2019 Chemical Science HOT Article Collection)

Gu, Y., Liu, B., Liu, Q., Hang, Y., Wang, L., Brash, J. L., Chen, G., Chen, H. (2019). Modular Polymers as a Platform for Cell Surface Engineering: Promoting Neural Differentiation and Enhancing the Immune Response. ACS Applied Materials & Interfaces, 11(51), 47720–47729. link

Wang, J., Liu, Y., Chen, R., Zhang, Z., Chen, G., Chen, H. (2019). Ultralow Self-Cross-Linked Poly( N -isopropylacrylamide) Microgels Prepared by Solvent Exchange. Langmuir, 35(43), 13991–13998. link

2018
Peng, L., Luo, Y., Zheng, Y., Zhang, W., & Chen, G. (2018). Sunlight-Induced RAFT Synthesis of Multifaceted Glycopolymers with Surface Anchoring, In Situ AgNP Formation, and Antibacterial Properties. ACS Applied Nano Materials, 1(5), 2219–2226. http://doi.org/10.1021/acsanm.8b00286
Wen, M., Liu, M., Xue, W., Yang, K., Chen, G., & Zhang, W. (2018). Simple and Green Strategy for the Synthesis of “Pathogen-Mimetic” Glycoadjuvant@AuNPs by Combination of Photoinduced RAFT and Bioinspired Dopamine Chemistry. ACS Macro Letters, 7(1), 70–74. http://doi.org/10.1021/acsmacrolett.7b00837
2017
Weng, Y., Li, Z., Peng, L., Zhang, W., & Chen, G. (2017). Fabrication of carbon quantum dots with nano-defined position and pattern in one step via sugar-electron-beam writing. Nanoscale, 9(48), 19263–19270. http://doi.org/10.1039/C7NR07892G
Hu, X., Gao, J., Luo, Y., Wei, T., Dong, Y., Chen, G., & Chen, H. (2017). One-Pot Multicomponent Synthesis of Glycopolymers through a Combination of Host-Guest Interaction, Thiol-ene, and Copper-Catalyzed Click Reaction in Water. Macromolecular Rapid Communications, 38(20), 1700434. http://doi.org/10.1002/marc.201700434
Peng, L., Zhou, S., Yang, B., Bao, M., Chen, G., & Zhang, X. (2017). Chemically Modified Surface Having a Dual-Structured Hierarchical Topography for Controlled Cell Growth. ACS Applied Materials & Interfaces, 9(28), 24339–24347. http://doi.org/10.1021/acsami.7b06197
Xue, W., Wang, J., Wen,M., Chen, G., & Zhang, W. (2017). Integration of CuAAC Polymerization andControlled Radical Polymerization into Electron Transfer Mediated“Click-Radical” Concurrent Polymerization. Macromolecular Rapid Communications, 38(6), 1600733.http://doi.org/10.1002/marc.201600733
Liu, Q., Lyu, Z., Yu,Y., Zhao, Z., Hu, S., Yuan, L., Chen, G., Chen, H. (2017). Synthetic Glycopolymers forHighly Efficient Differentiation of Embryonic Stem Cells into Neurons: Lipo- orNot? ACS Applied Materials & Interfaces, 9(13), 11518–11527.http://doi.org/10.1021/acsami.7b01397
Peng, L., Li, Z., Li,X., Xue, H., Zhang, W., & Chen, G. (2017). Integrating Sugar and Dopamineinto One Polymer: Controlled Synthesis and Robust Surface Modification. Macromolecular Rapid Communications, 38(3), 1600548.http://doi.org/10.1002/marc.201600548
Xue, H., Peng, L.,Dong, Y., Zheng, Y., Luan, Y., Hu, X., Chen, G., Chen, H. (2017). Synthesis ofstar-glycopolymers by Cu(0)-mediated radical polymerisation in the absence andpresence of oxygen. RSC Adv., 7(14), 8484–8490.http://doi.org/10.1039/C6RA28763H
2016
Liu, Q., Xue, H., Gao,J., Cao, L., Chen, G., & Chen, H. (2016). Synthesis of lipo-glycopolymersfor cell surface engineering. Polym. Chem., 7(47), 7287–7294.http://doi.org/10.1039/C6PY01788F
Wang, J., Rivero, M.,Mu?oz Bonilla, A., Sanchez-Marcos, J., Xue, W., Chen, G., … Zhu, X. (2016).Natural RAFT Polymerization: Recyclable-Catalyst-Aided, Opened-to-Air, andSunlight-Photolyzed RAFT Polymerizations. ACS Macro Letters, 5,1278–1282. http://doi.org/10.1021/acsmacrolett.6b00818
Li, Z., Zhang, P., Lu,W., Peng, L., Zhao, Y., & Chen, G. (2016). Ratiometric Fluorescent pHProbes Based on Glycopolymers. Macromolecular Rapid Communications, 37(18),1513–1519. http://doi.org/10.1002/marc.201600242
Xue, L., Xiong, X.,Chen, K., Luan, Y., Chen, G., & Chen, H. (2016). Modular synthesis ofglycopolymers with well-defined sugar units in the side chain via Ugi reactionand click chemistry: hetero vs. homo. Polym. Chem., 7(25),4263–4271. http://doi.org/10.1039/C6PY00734A
Cao, L., Shi, X., Cui,Y., Yang, W., Chen, G., Yuan, L., & Chen, H. (2016). Protein–polymerconjugates prepared via host–guest interactions: effects of the conjugationsite, polymer type and molecular weight on protein activity. Polym. Chem., 7(32), 5139–5146. http://doi.org/10.1039/C6PY00882H
Wang, J., Wang, X.,Xue, W., Chen, G., Zhang, W., & Zhu, X. (2016). Initiator andPhotocatalyst-Free Visible Light Induced One-Pot Reaction: Concurrent RAFTPolymerization and CuAAC Click Reaction. Macromolecular Rapid Communications, 37(9), 799–804. http://doi.org/10.1002/marc.201600004
Chen, K., Bao, M.,Mu?oz Bonilla, A., Zhang, W., & Chen, G. (2016). A biomimicking andelectrostatic self-assembly strategy for the preparation of glycopolymerdecorated photoactive nanoparticles. Polym. Chem., 7(14),2565–2572. http://doi.org/10.1039/C6PY00129G
Li, X., Zhang, W.,& Chen, G. (2016). Synthesis of Non-spherical Glycopolymer-DecoratedNanoparticles: Combing Thiol-ene with Catecholic Chemistry (Vol. 1367, pp.149–155). Springer. http://doi.org/10.1007/978-1-4939-3130-9_12
2015
Wang, S., Yuan, F.,Chen, K., Chen, G., Tu, K., Wang, H., & Wang, L.-Q. (2015). Synthesis ofHemoglobin Conjugated Polymeric Micelle: A ZnPc Carrier with OxygenSelf-Compensating Ability for Photodynamic Therapy. Biomacromolecules, 16(9),2693–2700. http://doi.org/10.1021/acs.biomac.5b00571
Shi, X., Zhan, W.,Chen, G., Yu, Q., Liu, Q., Du, H., … Chen, H. (2015). Regulation of ProteinBinding Capability of Surfaces via Host–Guest Interactions: Effects ofLocalized and Average Ligand Density. Langmuir, 31(22),6172–6178. http://doi.org/10.1021/acs.langmuir.5b01380
Yuan, F., Wang, S., Lu,W., Chen, G., Tu, K., Jiang, H., & Wang, L.-Q. (2015). Facile preparationof cancer-specific polyelectrolyte nanogels from natural and synthetic sugar polymers. J. Mater. Chem. B, 3(22), 4546–4554.http://doi.org/10.1039/C5TB00539F
Li, B., Wang, M., Chen,K., Cheng, Z., Chen, G., & Zhang, Z. (2015). Synthesis of BiofunctionalJanus Particles. Macromolecular Rapid Communications, 36(12),1200–1204. http://doi.org/10.1002/marc.201500063
Li, X., & Chen, G.(2015). Glycopolymer-based nanoparticles: synthesis and application. Polym.Chem., 6(9), 1417–1430. http://doi.org/10.1039/C4PY01740D
Xue, L., Lyu, Z., Luan,Y., Xiong, X., Pan, J., Chen, G., & Chen, H. (2015). Efficient cancer cellcapturing SiNWAs prepared via surface-initiated SET-LRP and click chemistry. Polym.Chem., 6(19), 3708–3715. http://doi.org/10.1039/C5PY00247H
2014
Li, X., Bao, M., Weng, Y., Yang, K., Zhang, W.*, & Chen, G.* (2014).Glycopolymer-coated iron oxide nanoparticles: shape-controlled synthesis andcellular uptake. Journal of Materials Chemistry B, 2(34), 5569.doi:10.1039/C4TB00852A
Li, X., Wang, L., Chen, G.*, Haddleton, D. M., & Chen, H.* (2014).Visible light induced fast synthesis of protein-polymer conjugates:controllable polymerization and protein activity. Chemical Communications, 50(49), 6506–8. doi:10.1039/c4cc02277g
Lu, J., Fu, C., Wang, S., Tao, L.*, Yan, L.*, Haddleton, D. M., Chen,G.*, Wei, Y. (2014). From Polymer Sequence Control to Protein Recognition:Synthesis, Self-Assembly and Lectin Binding. Macromolecules, 47(14),4676–4683. doi:10.1021/ma500664u
Lu, J., Zhang, W., Richards, S., Gibson, M. I., & Chen, G.* (2014).Glycopolymer-coated gold nanorods synthesised by a one pot copper(0) catalyzedtandem RAFT/click reaction. Polymer Chemistry, 5(7), 2326.doi:10.1039/c3py01526b
Lu, J., Zhang, W., Yuan, L., Ma, W., Li, X., Lu, W., Zhao, Y.*, Chen,G.* (2014). One-pot synthesis of glycopolymer-porphyrin conjugate as photosensitizerfor targeted cancer imaging and photodynamic therapy. Macromolecular Bioscience, 14(3), 340–6. doi:10.1002/mabi.201300451
Lu, W., Ma, W., Lu, J., Li, X., Zhao, Y.*, & Chen, G.* (2014).Microwave-assisted synthesis of glycopolymer-functionalized silvernanoclusters: combining the bioactivity of sugar with the fluorescence andcytotoxicity of silver. Macromolecular Rapid Communications, 35(8),827–33. doi:10.1002/marc.201300905
Shi, X., Chen, G.*, Yuan, L., Tang, Z., Liu, W., Zhang, Q.,Haddleton, D.*, Chen,H.* (2014). Integrating a thermoresponsive copolymer with host–guestinteractions for fabricating molecular recognition surfaces. Materials Horizons, 1(5), 540. doi:10.1039/C4MH00081A
Wang, J., Zhu, H., Chen, G., Hu, Z.*, Weng, Y., Wang, X., & Zhang, W.*(2014). Controlled synthesis and self-assembly of dopamine-containing copolymerfor honeycomb-like porous hybrid particles. Macromolecular Rapid Communications, 35(11), 1061–7. doi:10.1002/marc.201400029
Wang, L., Li, J., Zhang, W., Chen, G.*, Zhang, W.*, & Zhu, X. (2014).A novel approach to synthesize polymers for potential photodynamic therapy:from benzenedinitrile to phthalocyanine. Polymer Chemistry, 5(8),2872. doi:10.1039/c3py01129a
Xue, L., Lyu, Z., Shi, X., Tang, Z., Chen, G.*, & Chen, H.* (2014).Fast and Green Synthesis of a Smart Glyco-surface via Aqueous Single ElectronTransfer-Living Radical Polymerization. Macromolecular Chemistry and Physics, 215(15), 1491–1497. doi:10.1002/macp.201400227
Yuan, F., Wang, S., Chen, G.*, Tu, K., Jiang, H., & Wang, L.* (2014).Novel chitosan-based pH-sensitive and disintegrable polyelectrolyte nanogels. Colloidsand Surfaces. B, Biointerfaces, 122, 194–201.doi:10.1016/j.colsurfb.2014.06.042
Chen, G., Yang, J., Lu, G., Liu, P. C., Chen, Q., Xie, Z., & Wu, C.*(2014). One Stone Kills Three Birds: Novel Boron-Containing Vesicles forPotential BNCT, Controlled Drug Release, and Diagnostic Imaging. Molecular Pharmaceutics. doi:10.1021/mp400641u
Du, X., Wang, Y., Yuan, L.*, Weng, Y., Chen, G.*, & Hu, Z.* (2014).Guiding the behaviors of human umbilical vein endothelial cells with patternedsilk fibroin films. Colloids and Surfaces. B, Biointerfaces, 122,79–84. doi:10.1016/j.colsurfb.2014.06.049
Luo, F., Cheng, Z., Wang, M., Chen, G., & Zhang, Z.* (2014). Synthesisof soft colloids with well-controlled softness. Chemical Communications, 50(56), 7535–7. doi:10.1039/c4cc02485k
Liu, J., Li, J., Zhang, Z., Weng, Y., Chen, G., Yuan, B.*, … Ma, Y.*(2014). Encapsulation of Hydrophobic Phthalocyanine with Poly(N-isopropylacrylamide)/LipidComposite Microspheres for Thermo-Responsive Release and Photodynamic Therapy. Materials, 7(5), 3481–3493. doi:10.3390/ma7053481
Wang, Z., Chen, G., Lu, J., Hong, L.*, & Ngai, T.* (2013).Investigation of the factors affecting the carbohydrate–lectin interaction byITC and QCM-D. Colloid and Polymer Science, 292(2), 391–398.doi:10.1007/s00396-013-3080-0
Liu, X., Yuan, L., Li, D., Tang, Z., Wang, Y., Chen, G., Chen,H.*, Brash, J. L.* (2014). Blood compatible materials: state of the art. Journalof Materials Chemistry B, 2(35), 5718. doi:10.1039/C4TB00881B
Tan, M., Wang, H., Wang, Y., Chen, G., Yuan, L.*, & Chen, H.* (2014).Recyclable antibacterial material: silicon grafted with 3,6-O-sulfated chitosanand specifically bound by lysozyme. Journal of Materials Chemistry B, 2(5),569. doi:10.1039/c3tb21358g
2013
Li, J., Zhang, W., Hu, Z., Jiang, X.-J., Ngai, T., Lo, P.-C., Zhang,W., Chen, G.* (2013). Novel phthalocyanine and PEG-methacrylates basedtemperature-responsive polymers for targeted photodynamic therapy. Polymer Chemistry, 4(3), 782. doi:10.1039/c2py20668d
Shi, X., Chen, G.*, Wang, Y., Yuan, L., Zhang, Q., Haddleton, D. M., &Chen, H.* (2013). Control the wettability ofpoly(n-isopropylacrylamide-co-1-adamantan-1-ylmethyl acrylate) modifiedsurfaces: the more Ada, the bigger impact? Langmuir, 29(46), 14188–95.doi:10.1021/la4037748
2012
Shen, Q., Zhang, J., Zhang, S., Hao, Y., Zhang, W.*, Zhang, W., Chen, G.,Zhang, Z., Zhu, X.* (2012). Facile one-pot/one-step technique forpreparation of side-chain functionalized polymers: Combination of SET-RAFT polymerizationof azide vinyl monomer and click chemistry. Journal of Polymer Science PartA: Polymer Chemistry, 50(6), 1120–1126.
Zhang, W., Chen, G., Hu, Z., Zhang, W., Zhang, Z., & Zhu, X.* (2012).Precisely controlled copper(0)-catalyzed one-pot reaction: Concurrent livingradical polymerization and click chemistry. Journal of Polymer Science PartA: Polymer Chemistry, 50(17), 3656–3663.
2011
Huynh, V. T., Chen, G., Souza, P. De, & Stenzel, M. H.* (2011).Thiol-yne and Thiol-ene “Click” Chemistry as a Tool for a Variety of PlatinumDrug Delivery Carriers, from Statistical Copolymers to Crosslinked Micelles. Biomacromolecules, 12(5), 1738–51. doi:10.1021/bm200135e
Kumar, J., McDowall, L., Chen, G., & Stenzel, M. H.* (2011). Synthesisof thermo-responsive glycopolymers via copper catalysed azide–alkyne “click”chemistry for inhibition of ricin: the effect of spacer between polymerbackbone and galactose. Polymer Chemistry, 2(8), 1879–1886.doi:10.1039/c1py00048a
Pearson, S., Chen, G., & Stenzel, M. H.* (2011). Synthesis ofGlycopolymers. In R. Narain (Ed.), Engineered Carbohydrate-Based Materialsfor Biomedical Applications (pp. 1–118). John Wiley & Sons.doi:10.1002/9780470944349.ch1
Tao, L., Chen, G., Zhao, L., Xu, J., Huang, E., Liu, A., … Davis, T. P.* (2011).Protein release from biodegradable polyHPMA-lysozyme conjugates resulting inbioactivity enhancement. Chemistry, an Asian Journal, 6(6),1398–404. doi:10.1002/asia.201000729
Wang, J., Yue, Y., Chen, G., & Xia, J.* (2011). Protease-promoted drugdelivery using peptide-functionalized gold nanoparticles. Soft Matter, 7(16),7217. doi:10.1039/c1sm05242j
Zhang, W., Zhang, W., Cheng, Z., Zhou, N., Zhu, J., Zhang, Z., Chen,G., Zhu, X.* (2011). Synthesis and Aggregation Behaviors of NonlinearMultiresponsive, Multihydrophilic Block Copolymers. Macromolecules, 44(9),3366–3373. doi:10.1021/ma200083v
2010
Chen, Y., Chen, G., & Stenzel, M. H.* (2010). Synthesis and LectinRecognition of Glyco Star Polymers Prepared by “Clicking” Thiocarbohydratesonto a Reactive Scaffold. Macromolecules, 43(19), 8109–8114.doi:10.1021/ma100919x
Hetzer, M., Chen, G., Barner-Kowollik, C., & Stenzel, M. H.* (2010).Neoglycopolymers based on 4-vinyl-1,2,3-triazole monomers prepared by clickchemistry. Macromolecular Bioscience, 10(2), 119–26.doi:10.1002/mabi.200900199
Ting, S., Chen, G., & Stenzel, M. H.* (2010). Synthesis ofglycopolymers and their multivalent recognitions with lectins. Polymer Chemistry, 1(9), 1392. doi:10.1039/c0py00141d
before 2010
Chen, G., Amajjahe, S., & Stenzel, M. H. (2009). Synthesis ofthiol-linked neoglycopolymers and thermo-responsive glycomicelles as potentialdrug carrier. Chemical Communications, (10), 1198–200.doi:10.1039/b900215d
Chen, G., Kumar, J., Gregory, A., & Stenzel, M. H. (2009). Efficientsynthesis of dendrimers via a thiol-yne and esterification process and theirpotential application in the delivery of platinum anti-cancer drugs. Chemical Communications, 12(41), 6291–3. doi:10.1039/b910340f
Chen, G., Tao, L., Mantovani, G., Geng, J., Nystr?m, D., & Haddleton,D. M. (2007). A Modular Click Approach to Glycosylated Polymeric Beads: Design,Synthesis and Preliminary Lectin Recognition Studies. Macromolecules, 40(21),7513–7520. doi:10.1021/ma071362v
Chen, G., Tao, L., Mantovani, G., Ladmiral, V., Burt, D. P., Macpherson,J. V., & Haddleton, D. M. (2007). Synthesis of azide/alkyne-terminalpolymers and application for surface functionalisation through a [2 + 3]Huisgen cycloaddition process,??click chemistry? Soft Matter, 3(6),732. doi:10.1039/b618325e
Chen, G., Wright, P. M., Geng, J., Mantovani, G., & Haddleton, D. M.(2008). Tunable thermoresponsive water-dispersed multiwalled carbon nanotubes. Chemical Communications, (9), 1097–9. doi:10.1039/b718112d
Chen, G., Zhu, X., Zhu, J., & Cheng, Z. (2004). Plasma-InitiatedControlled/Living Radical Polymerization of Methyl Methacrylate in the Presenceof 2-Cyanoprop-2-yl 1-dithionaphthalate(CPDN). Macromolecular Rapid Communications, 25(7), 818–824. doi:10.1002/marc.200300266
Geng, J., Lindqvist, J., Mantovani, G., Chen, G., Sayers, C. T., Clarkson,G. J., & Haddleton, D. M. (2007). Well-Defined Poly(N-glycosyl1,2,3-triazole) Multivalent Ligands: Design, Synthesis and Lectin BindingStudies. QSAR & Combinatorial Science, 26(11-12), 1220–1228.doi:10.1002/qsar.200740089
Geng, J., Mantovani, G., Tao, L., Nicolas, J., Chen, G., Wallis, R., …Haddleton, D. M. (2007). Site-directed conjugation of “clicked” glycopolymersto form glycoprotein mimics: binding to mammalian lectin and induction ofimmunological function. Journal of the American Chemical Society, 129(49),15156–63. doi:10.1021/ja072999x
Gu, W., Chen, G., & Stenzel, M. H. (2009). Synthesis ofglyco-microspheres via a thiol-ene coupling reaction. Journal of Polymer Science Part A: Polymer Chemistry, 47(20), 5550–5556.doi:10.1002/pola.23615
McDowall, L., Chen, G., & Stenzel, M. H. (2008). Synthesis ofSeven-Arm Poly(vinyl pyrrolidone) Star Polymers with Lysozyme Core Prepared byMADIX/RAFT Polymerization. Macromolecular Rapid Communications, 29(20),1666–1671. doi:10.1002/marc.200800416
Tao, L., Chen, G., Mantovani, G., York, S., & Haddleton, D. M. (2006).Modification of multi-wall carbon nanotube surfaces with poly(amidoamine)dendrons: synthesis and metal templating. Chemical Communications, (47),4949–51. doi:10.1039/b609065f
Tao, L., Geng, J., Chen, G., Xu, Y., Ladmiral, V., Mantovani, G., &Haddleton, D. M. (2007). Bioconjugation of biotinylated PAMAM dendrons toavidin. Chemical Communications, (33), 3441–3. doi:10.1039/b709080c
Withey, A. B. J., Chen, G., Nguyen, T. L. U., & Stenzel, M. H. (2009).Macromolecular cobalt carbonyl complexes encapsulated in a click-cross-linkedmicelle structure as a nanoparticle to deliver cobalt pharmaceuticals. Biomacromolecules, 10(12), 3215–26. doi:10.1021/bm901050x
Xu, W., Zhu, X., Cheng, Z., Chen, G., & Zhu, J. (2005). Polymerizationof styrene with tetramethylthiuram disulfide as an initiator in the presence of2,2,6,6-tetramethyl-1-piperidinyloxy. Journal of Polymer Science Part A:Polymer Chemistry, 43(3), 543–551. doi:10.1002/pola.20533
本课题组现招收有志于科研工作的研究生及博士后。招生方向包括化学(高分子化学与物理、材料化学),材料科学与工程等,欢迎具有化学、材料背景的同学报考。
