高玉振，医学博士，苏州大学医学部法医学系教授。2000年毕业于华西医科大学法医学专业，2003年毕业于四川大学（原华西医科大学）法医遗传学专业，获医学硕士学位。近年来一直致力于人类分子遗传学相关研究，特别是人类短串连重复序列（STR）遗传标记、SNPs 及插入缺失多态的群体遗传学研究和疾病关联性研究。2005年9月至2006年9月在日本昭和大学访问学者。2008年3月至2010年2月在苏州大学基础医学博士后流动站从事肿瘤病因的遗传分子机制研究。
中国遗传学会法医遗传学分会 委员
国际法医遗传学会（ISFG）会员
苏州大学司法鉴定中心司法鉴定人
Cancer,
British Journal of Cancer,
Annals of Surgical Oncology,
International Journal of Cardiology,
Forensic Science International,
BMJ Oncology,
Journal of ImmunoTherapy of Cancer等杂志审稿人
1、法医分子遗传学
2、心源性猝死分子遗传学
3、肿瘤分子遗传学
近年来一直致力于人类分子遗传学相关研究，特别是人类短串连重复序列（STR）遗传标记、SNPs 及插入缺失多态的群体遗传学研究和疾病关联性研究。至今以第一作者或通讯作者身份共发表SCI论文近20篇。
科研项目
2009-1至2011-12 肝细胞肝癌相关基因中miRNA结合靶点内SNPs的筛选及功能分析 （NSFC No.30800621）
2012-1至2015-12 肿瘤相关基因中微小插入缺失多态与肝细胞肝癌的关联性研究及功能分析 （NSFC No.81171893）
2016-1至2019-12 MicroRNA-3131及其遗传多态在肝细胞肝癌发生发展中的作用机制研究 （NSFC No.81572767）
2018-1至2021-12 miR155HG基因及其遗传多态在心源性猝死发生中的分子机制研究 （NSFC No.81772029）
课题组成员
李立娟 讲师 博士
毕业研究生
陈守恭 （就职单位：上饶市人民检察院）
姜玉婷 （就职单位：烟台市公安局）
赵宪坤 （就职单位：齐鲁制药有限公司）
陶瑞旸（就职单位：司法部司法鉴定科学技术研究所）
李丽（就职单位：苏州市立医院司法鉴定所）
王守宇（博士就读单位：四川大学）
在读研究生（法医学）
尹志霞 张晴 陈雪坤
联合培养研究生
王超群（神经生物学） 胡书祥（神经生物学） 郭四平（神经病学） 江玲玲（神经病学） 贾莎莎（神经病学） 路丹丹（皮肤病学）邹燕（法医学）杨丹丹（法医学）
参编教材：
十三五规划教材《法医物证学》第四版（侯一平 主编）
讲授课程：
1. 法医学专业 《法医物证学》、《法医人类学》
2. 全校公选课《法医学》
3. 留学生《法医学》
1.Zou Y, Zhang Q, Zhang J, Chen X, Zhou W, Yang Z, Yang Q, Yu H, Li L, He Y, Li C, Zhang S, Zhu S, Luo B, Gao Y. A common indel polymorphism of the Desmoglein-2 (DSG2) is associated with sudden cardiac death in Chinese populations. Forensic Sci Int. 2019; 301:382-387.
2. Wang S, Li L, Tao R, Gao Y. Ion channelopathies associated genetic variants as the culprit for sudden unexplained death. Forensic Sci Int. 2017;275:128-137.
3. Yin Z, Guo Y, Zhang J, Zhang Q, Li L, Wang S, Wang C, He Y, Zhu S, Li C, Zhang S, Zha L, Cai J, Luo B, Gao Y. Association between an indel polymorphism in the 3'UTR of COL1A2 and the risk of sudden cardiac death in Chinese populations. Leg Med (Tokyo). 2017;28:22-26.
4. Wang C, Li L, Yin Z, Zhang Q, Zhao H, Tao R, Wang S, Hu S, He Y, Wang D, Li C, Zhang S, Xu J, Jiang X, Zhu S, Gao Y. An Indel Polymorphism within pre-miR3131 Confers Risk for Hepatocellular Carcinoma. Carcinogenesis. 2017; 38:168-76.
5. Wang S, Zhang Z, Yang Y, Wang C, Tao R, Hu S, Yin Z, Zhang Q, Li L, He Y, Zhu S, Li C, Zhang S, Zhang J, Sheng L, Wu F, Luo B, Gao Y. An insertion/deletion polymorphism within 3'UTR of RYR2 modulates sudden unexplained death risk in Chinese populations. Forensic Sci Int. 2017;270:165-72.
6.Tao R, Hu S, Wang S, Zhou X, Zhang Q, Wang C, Zhao X, Zhou W, Zhang S, Li C, Zhao H, He Y, Zhu S, Xu J, Jiang Y, Li L, Gao Y.Association between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma. Carcinogenesis. 2015;36:1136-43.
7.Hu S, Tao R, Wang S, Wang C, Zhao X, Zhao H, Li L, Zhu S, He Y, Jiang X, Gao Y. MicroRNA-21 promotes cell proliferation in human hepatocellular carcinoma partly by targeting HEPN1.Tumour Biol. 2015; 36:5467–5472.
8. Zhao X, Hu S, Wang L, Zhang Q, Zhu X, Zhao H, Wang C, Tao R, Guo S, Wang J, Xu J, He Y, Gao Y. Functional short tandem repeat polymorphism of PTPN11 and susceptibility to hepatocellular carcinoma in Chinese populations. PLoS One. 2014 Sep 8;9(9):e106841.
9. Wan J, Huang M, Zhao H, Wang C, Zhao X, Jiang X, Bian S, He Y, Gao Y. A novel tetranucleotide repeat polymorphism within KCNQ1OT1 confers risk for hepatocellular carcinoma. DNA Cell Biol. 2013;32:628-34.
10. Wang C, Zhao H, Zhao X, Wan J, Wang D, Bi W, Jiang X, Gao Y. Association between an insertion/deletion polymorphism within 3'UTR of SGSM3 and risk of hepatocellular carcinoma.Tumour Biol. 2014;35:295-301.
11. Gao X, Huang M, Liu L, He Y, Yu Q, Zhao H, Zhou C, Zhang J, Zhu Z, Wan J, Jiang X, Gao Y. Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations. PLoS One. 2013;8(1):e55169.
12. Zhu Z, Gao X, He Y, Zhao H, Yu Q, Jiang D, Zhang P, Ma X, Huang H, Dong D, Wan J, Gu Z, Jiang X, Yu L, Gao Y. An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res. 2012;72:6163-72.
13. Jiang L, Xu J, Ni J, Gao X, Zhu Z, Dong D, Wang X, Shi C, Tao X, Dong W, Gao Y. A functional insertion/deletion polymorphism in the proximal promoter of CD3G is associated with susceptibility for hepatocellular carcinoma in Chinese population. DNA Cell Biol. 2012;31:1480-5.
14. Dong D, Gao X, Zhu Z, Yu Q, Bian S, Gao Y. A 40-bp insertion/deletion polymorphism in the constitutive promoter of MDM2 confers risk for hepatocellular carcinoma in a Chinese population. Gene. 2012;497:66-70.
15. Zhu Z, Jiang Y, Chen S, Jia S, Gao X, Dong D, Gao Y. An insertion/deletion polymorphism in the 3' untranslated region of type I collagen a2 (COL1A2) is associated with susceptibility for hepatocellular carcinoma in a Chinese population. Cancer Genet. 2011;204:265-9.
16. Jiang Y, Chen S, Jia S, Zhu Z, Gao X, Dong D, Gao Y. Association of HLA-G 3' UTR 14-bp insertion/deletion polymorphism with hepatocellular carcinoma susceptibility in a Chinese population. DNA Cell Biol. 2011;30:1027-32.
17. Jia S, Ni J, Chen S, Jiang Y, Dong W, Gao Y. Association of the pentanucleotide repeat polymorphism in NOS2 promoter region with susceptibility to migraine in a Chinese population. DNA Cell Biol. 2011;30:117-22.
18. Ni JQ, Jia SS, Liu M, Chen SG, Jiang YT, Dong WL, Gao YZ. Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population. Neurosci Bull. 2010;26:322-6.
19. Chen S, He Y, Ding J, Jiang Y, Jia S, Xia W, Zhao J, Lu M, Gu Z, Gao Y.An insertion/deletion polymorphism in the 3' untranslated region of beta-transducin repeat-containing protein (betaTrCP) is associated with susceptibility for hepatocellular carcinoma in Chinese.Biochem Biophys Res Commun. 2010;391:552-6.
20. Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S, Zhou Y, Liu H.An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma. Carcinogenesis. 2009;30:2064-9.
21.Gao Y, Zhang Z, Wang Z, Bian S.Genetic data of 15 STR forensic loci in eastern Chinese population. Forensic Sci Int. 2005;154:78-80.
法医学专业学术型研究生：法医分子遗传学（法医DNA分析方向）
高玉振，医学博士，苏州大学医学部法医学系教授。2000年毕业于华西医科大学法医学专业，2003年毕业于四川大学（原华西医科大学）法医遗传学专业，获医学硕士学位。近年来一直致力于人类分子遗传学相关研究，特别是人类短串连重复序列（STR）遗传标记、SNPs 及插入缺失多态的群体遗传学研究和疾病关联性研究。2005年9月至2006年9月在日本昭和大学访问学者。2008年3月至2010年2月在苏州大学基础医学博士后流动站从事肿瘤病因的遗传分子机制研究。
中国遗传学会法医遗传学分会 委员
国际法医遗传学会（ISFG）会员
苏州大学司法鉴定中心司法鉴定人
Cancer,
British Journal of Cancer,
Annals of Surgical Oncology,
International Journal of Cardiology,
Forensic Science International,
BMJ Oncology,
Journal of ImmunoTherapy of Cancer等杂志审稿人
1、法医分子遗传学
2、心源性猝死分子遗传学
3、肿瘤分子遗传学
近年来一直致力于人类分子遗传学相关研究，特别是人类短串连重复序列（STR）遗传标记、SNPs 及插入缺失多态的群体遗传学研究和疾病关联性研究。至今以第一作者或通讯作者身份共发表SCI论文近20篇。
科研项目
2009-1至2011-12 肝细胞肝癌相关基因中miRNA结合靶点内SNPs的筛选及功能分析 （NSFC No.30800621）
2012-1至2015-12 肿瘤相关基因中微小插入缺失多态与肝细胞肝癌的关联性研究及功能分析 （NSFC No.81171893）
2016-1至2019-12 MicroRNA-3131及其遗传多态在肝细胞肝癌发生发展中的作用机制研究 （NSFC No.81572767）
2018-1至2021-12 miR155HG基因及其遗传多态在心源性猝死发生中的分子机制研究 （NSFC No.81772029）
课题组成员
李立娟 讲师 博士
毕业研究生
陈守恭 （就职单位：上饶市人民检察院）
姜玉婷 （就职单位：烟台市公安局）
赵宪坤 （就职单位：齐鲁制药有限公司）
陶瑞旸（就职单位：司法部司法鉴定科学技术研究所）
李丽（就职单位：苏州市立医院司法鉴定所）
王守宇（博士就读单位：四川大学）
在读研究生（法医学）
尹志霞 张晴 陈雪坤
联合培养研究生
王超群（神经生物学） 胡书祥（神经生物学） 郭四平（神经病学） 江玲玲（神经病学） 贾莎莎（神经病学） 路丹丹（皮肤病学）邹燕（法医学）杨丹丹（法医学）
参编教材：
十三五规划教材《法医物证学》第四版（侯一平 主编）
讲授课程：
1. 法医学专业 《法医物证学》、《法医人类学》
2. 全校公选课《法医学》
3. 留学生《法医学》
1.Zou Y, Zhang Q, Zhang J, Chen X, Zhou W, Yang Z, Yang Q, Yu H, Li L, He Y, Li C, Zhang S, Zhu S, Luo B, Gao Y. A common indel polymorphism of the Desmoglein-2 (DSG2) is associated with sudden cardiac death in Chinese populations. Forensic Sci Int. 2019; 301:382-387.
2. Wang S, Li L, Tao R, Gao Y. Ion channelopathies associated genetic variants as the culprit for sudden unexplained death. Forensic Sci Int. 2017;275:128-137.
3. Yin Z, Guo Y, Zhang J, Zhang Q, Li L, Wang S, Wang C, He Y, Zhu S, Li C, Zhang S, Zha L, Cai J, Luo B, Gao Y. Association between an indel polymorphism in the 3'UTR of COL1A2 and the risk of sudden cardiac death in Chinese populations. Leg Med (Tokyo). 2017;28:22-26.
4. Wang C, Li L, Yin Z, Zhang Q, Zhao H, Tao R, Wang S, Hu S, He Y, Wang D, Li C, Zhang S, Xu J, Jiang X, Zhu S, Gao Y. An Indel Polymorphism within pre-miR3131 Confers Risk for Hepatocellular Carcinoma. Carcinogenesis. 2017; 38:168-76.
5. Wang S, Zhang Z, Yang Y, Wang C, Tao R, Hu S, Yin Z, Zhang Q, Li L, He Y, Zhu S, Li C, Zhang S, Zhang J, Sheng L, Wu F, Luo B, Gao Y. An insertion/deletion polymorphism within 3'UTR of RYR2 modulates sudden unexplained death risk in Chinese populations. Forensic Sci Int. 2017;270:165-72.
6.Tao R, Hu S, Wang S, Zhou X, Zhang Q, Wang C, Zhao X, Zhou W, Zhang S, Li C, Zhao H, He Y, Zhu S, Xu J, Jiang Y, Li L, Gao Y.Association between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma. Carcinogenesis. 2015;36:1136-43.
7.Hu S, Tao R, Wang S, Wang C, Zhao X, Zhao H, Li L, Zhu S, He Y, Jiang X, Gao Y. MicroRNA-21 promotes cell proliferation in human hepatocellular carcinoma partly by targeting HEPN1.Tumour Biol. 2015; 36:5467–5472.
8. Zhao X, Hu S, Wang L, Zhang Q, Zhu X, Zhao H, Wang C, Tao R, Guo S, Wang J, Xu J, He Y, Gao Y. Functional short tandem repeat polymorphism of PTPN11 and susceptibility to hepatocellular carcinoma in Chinese populations. PLoS One. 2014 Sep 8;9(9):e106841.
9. Wan J, Huang M, Zhao H, Wang C, Zhao X, Jiang X, Bian S, He Y, Gao Y. A novel tetranucleotide repeat polymorphism within KCNQ1OT1 confers risk for hepatocellular carcinoma. DNA Cell Biol. 2013;32:628-34.
10. Wang C, Zhao H, Zhao X, Wan J, Wang D, Bi W, Jiang X, Gao Y. Association between an insertion/deletion polymorphism within 3'UTR of SGSM3 and risk of hepatocellular carcinoma.Tumour Biol. 2014;35:295-301.
11. Gao X, Huang M, Liu L, He Y, Yu Q, Zhao H, Zhou C, Zhang J, Zhu Z, Wan J, Jiang X, Gao Y. Insertion/deletion polymorphisms in the promoter region of BRM contribute to risk of hepatocellular carcinoma in Chinese populations. PLoS One. 2013;8(1):e55169.
12. Zhu Z, Gao X, He Y, Zhao H, Yu Q, Jiang D, Zhang P, Ma X, Huang H, Dong D, Wan J, Gu Z, Jiang X, Yu L, Gao Y. An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res. 2012;72:6163-72.
13. Jiang L, Xu J, Ni J, Gao X, Zhu Z, Dong D, Wang X, Shi C, Tao X, Dong W, Gao Y. A functional insertion/deletion polymorphism in the proximal promoter of CD3G is associated with susceptibility for hepatocellular carcinoma in Chinese population. DNA Cell Biol. 2012;31:1480-5.
14. Dong D, Gao X, Zhu Z, Yu Q, Bian S, Gao Y. A 40-bp insertion/deletion polymorphism in the constitutive promoter of MDM2 confers risk for hepatocellular carcinoma in a Chinese population. Gene. 2012;497:66-70.
15. Zhu Z, Jiang Y, Chen S, Jia S, Gao X, Dong D, Gao Y. An insertion/deletion polymorphism in the 3' untranslated region of type I collagen a2 (COL1A2) is associated with susceptibility for hepatocellular carcinoma in a Chinese population. Cancer Genet. 2011;204:265-9.
16. Jiang Y, Chen S, Jia S, Zhu Z, Gao X, Dong D, Gao Y. Association of HLA-G 3' UTR 14-bp insertion/deletion polymorphism with hepatocellular carcinoma susceptibility in a Chinese population. DNA Cell Biol. 2011;30:1027-32.
17. Jia S, Ni J, Chen S, Jiang Y, Dong W, Gao Y. Association of the pentanucleotide repeat polymorphism in NOS2 promoter region with susceptibility to migraine in a Chinese population. DNA Cell Biol. 2011;30:117-22.
18. Ni JQ, Jia SS, Liu M, Chen SG, Jiang YT, Dong WL, Gao YZ. Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population. Neurosci Bull. 2010;26:322-6.
19. Chen S, He Y, Ding J, Jiang Y, Jia S, Xia W, Zhao J, Lu M, Gu Z, Gao Y.An insertion/deletion polymorphism in the 3' untranslated region of beta-transducin repeat-containing protein (betaTrCP) is associated with susceptibility for hepatocellular carcinoma in Chinese.Biochem Biophys Res Commun. 2010;391:552-6.
20. Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S, Zhou Y, Liu H.An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma. Carcinogenesis. 2009;30:2064-9.
21.Gao Y, Zhang Z, Wang Z, Bian S.Genetic data of 15 STR forensic loci in eastern Chinese population. Forensic Sci Int. 2005;154:78-80.
法医学专业学术型研究生：法医分子遗传学（法医DNA分析方向）