杨晨，苏州大学骨科研究所副教授。2018年获中国科学院上海硅酸盐研究所材料学博士学位，先后在深圳大学、中国科学院大学温州研究院从事博士后及副研究员工作。2025年加入苏州大学骨科研究所。研究方向聚焦生物活性材料与难愈性组织损伤修复。目前以第一/通讯作者（含共同）身份在Advanced Materials、Advanced Functional Materials、Advanced Science、Biomaterials、Bioactive Materials、Exploration、Science Bulletin等国际专业期刊上发表SCI论文近50篇。已申请国家发明专利22项（其中已授权14项）。主持国家自然科学基金面上项目（2项）/青年基金、国家重点研发计划子课题、浙江省自然科学基金重点项目等科研项目10余项，并与多家企业开展产学研合作。担任Scientific Reports、Clinical and Experimental Pharmacology and Physiology期刊编委；Regenerative Biomaterials、Biomaterials Translational等期刊青年编委。现任中国生物材料学会生物陶瓷分会委员、中国生物材料学会烧创伤创面修复材料分会委员、中国生物医学工程学会生物材料分会委员、中国抗癌协会纳米肿瘤学专业委员会青年委员。入选深圳市海外高层次人才、温州市“瓯越海智计划”青年人才。担任Nature Communications,Advanced Materials等期刊审稿人。
近五年发表论文（#共同第一作者，*共同通讯作者）
1.Zhaoxu Meng#, Zhen Zeng#, Zhaowenbin Zhang, Lefeng Su, Huili Li, Chunlong Zhang, Hanjiao Chen, Xinyi Wang, Jiang Chang, Yingbo Wang*, Kui Luo*, Chen Yang*. Osteogenic nanozymes for diabetic bone regeneration via synergistic antioxidant and osteoinductive functions. Advanced Materials, 2026, 0, e72833.
2.Bo Li#, Dandan Jin#, Fei Li, Jianliang Shen, Jiang Chang, Chen Yang*, Shixuan Chen*, Yi Zhang*. A “hot spring” mimetic aerogel loaded with multiple amino acids modulates the chronic inflammatory microenvironment through metabolic reprogramming. Advanced Science, 2026, 0, e22481.
3.Ruqi Wang#, Qishu Jin#, Zhaoxu Meng, Xiaodong Cao, Yihao Wu, Chen Yang*, Jiandong Yuan*. Baicalein-manganese nanoparticles for antioxidant and osteogenic therapy of bone injury. Colloids and Surfaces B: Biointerfaces, 2026, 260, 115400.
4.Chen Yang#*, Chenle Dong#, Lefeng Su#, Zhiqiang Liu#, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang*, Jiandong Yuan*. A universal metal-flavonoid coating strategy: Engineering biomaterials for diabetic bone regeneration. Advanced Science, 2026, 13, e22509.
5.Zhen Zeng#, Zhaowenbin Zhang#, Lan Chang, Hanjiao Chen, Long Reng, Zhiqiang Huang, Yiren Jiao, Hangbin Xia, Chen Yang*, Kui Luo*, Jiang Chang*. Therapeutic silicate biomaterials for sarcopenia treatment by inhibiting inflammation and enhancing muscle regeneration through regulation of Sarcolipin/SIRT signaling pathway. Bioactive Materials, 2025, 51, 787-806.
6.Ming Teng, Xiaomin Luo*, Jiang Chang*, Chen Yang, Xiaomeng Zhang, Liuying Li, Xudan Liu, Ruizhi Zhi, Xu Guo, Xinhua Liu*. Engineering encapsulated living bacteria for advanced healthcare management. Biotechnology Advances, 2025, 83, 108640.
7.Xuening Jin#, Yihao Wu#, Zheng Chen#, Fujin Zhou, Qishu Jin, Shuting Wu, Yanping Feng, Jianfeng Ma, Xiaohui Guo, Jiang Chang*, Chen Yang*, Botao Song*. Bioinspired nanofiber dressings with counter-transport of exudate and drug for treating heavily exuding wounds. Biomaterials, 2025,317, 123084.
8.Xianwen Lu, Sitong Hu, Zhaowenbin Zhang, Jing Bao, Bangping Cao, Jian Xie, Jiang Chang, Chen Yang*, Xiaohong Wang*, Jiansheng Su*. A pH-sensitive CuHP composite hydrogel featuring antibacterial, antioxidant, and osteogenic properties for treating diabetic periodontitis. Regenerative Biomaterials, 2025, 12, rbaf065.
9.Chengxiao Liu#, Bin Yu#, Zhaowenbin Zhang#, Lefeng Su, Ruiqing Wang, Yu Jin, Weiming Guo, Ruomei Li, Zhen Zeng, Peng Mei, Jiang Chang, Lunguo Xia*, Chen Yang*, Bing Fang*. LIPUS activated piezoelectric pPLLA/SrSiO3 composite scaffold promotes osteochondral regeneration through P2RX1 mediated Ca2+ signaling pathway. Biomaterials, 2025,317, 123084.
10.Ping Sun#, Zhaowenbin Zhang#, Fei Gao, Chen Yang, Ge Mang, Shuai Fu, Jiawei Tian*, Jiang Chang*. Silicate-based therapy for inflammatory dilated cardiomyopathy by inhibiting vicious cycle of immune inflammation via FOXO signaling. Science Advances, 2025, 11, eadr7208.
11.Jupei Zhang#, Hangbin Xia#, Xuerui Zhou#, Zhaoxu Meng, Qishu Jin, Dongmin Chen, Xiaojuan Xia, Yiren Jiao, Jiang Chang, Zhihong Dong*, Zhen Zeng*, Hongshi Ma*, Chen Yang*. 3D-Printed CoSi/PCL composite scaffold with NIR-II photothermal ability and enhanced adipogenic activity for breast reconstruction after mastectomy.Materials Today Bio, 2025, 31, 101577.
12.Dongmin Chen#, Xiaosheng Sheng#, Huili Li, Qishu Jin, Ruqi Wanga, Yuanzheng Qiu, Lefeng Su, Jinfeng Xu, Jiang Chang*, Yumei Que*, Chen Yang*. Biodegradable copper-containing mesoporous microspheres loaded with ginsenoside Rb1 for infarcted heart repair. Biomaterials Advances, 2025, 169, 214172.
13.Lian-Hua Fu#, Mengting Yin#, Xin Chen#, Chen Yang, Jing Lin, Xiansong Wang*, Baoguo Jiang*, and Peng Huang*. Targeted Management of Diabetic Osteoporosis by Biocatalytic Cascade Reaction Nanoplatform. Nano Letters, 2025, 25, 3075-3084.
14.Hangbin Xia#, Chen Yang#*, Huili Li#, Lingwei Huang, Zhen Zeng, Runrun Chi, Ziwei Yang, Yuzen Wang, Jiang Chang*, Yiren Jiao*, Wenzhong Li*. Combined magnesium and silicate ions synergistically promote functional regeneration of skeletal muscle by regulating satellite cell fate. Regenerative Biomaterials, 2025, 12, rbaf008.
15.Zizhao Chen#, Pingping Feng#, Ruqi Wang#, Dongmin Chen, Chunmei Feng, Qishu Jin, Chen Yang*, Botao Song*. Bioinspired shape-changing nanofiber dressings for intelligent wrapping and promoting healing of superficial wounds. Colloids and Surfaces B: Biointerfaces, 2025, 245, 114246.
16.Zhaowenbin Zhang#, Chen Fan#, Qing Xu#, Feng Guo#, Wenbo Li#, Zhen Zeng, Yuze Xu, Jing Yu, Hongping Ge, Chen Yang*, Jiang Chang*. A new strategy to inhibit scar formation by accelerating normal healing using silicate bioactive materials. Advanced Science, 2024, 11, 2407718.
17.Xiaomin Luo#*, Lufeng Ji, Fen Ao, Chen Yang, Jiang Chang, Changyu Yin, Huijun Ren, Ming Teng, Liuying Li, Xinhua Liu*. On-demand engineered double-network gelatin/silicate composited hydrogels with enhanced wet adhesion and stable release of bioactive ion for promoting wound healing. Collagen and Leather, 2024, 6, 18.
18.Pengli Wang#, Erji Gao#, Tao Wang#, Yanping Feng, Yong Xu, Lefeng Su, Wei Gao, Zheng Ci, Muhammad Rizwan Younis, Jiang Chang*, Chen Yang*, Liang Duan*.Copper hydrogen phosphate nanosheets functionalized hydrogel with tissue adhesive, antibacterial, and angiogenic capabilities for tracheal mucosal regeneration.Journal of Nanobiotechnology, 2024, 22, 652.
19.Lili Sheng#, Yanping Feng#, Shuting Wu#, Chen Wang#, Ruiyang Sun, Qishu Jin, Dongmin Chen, Zhaowenbin Zhang, He Xu*, Zhihong Dong*, Hong Zhu*, Chen Yang*, Jiang Chang. Biodegradable copper vanadate-based hydrogel with photocatalytic/photothermal therapy for infected diabetic wound healing. Materials & Design, 2024, 246, 113358.
20.Lingwei Huan#, Yiren Jiao#, Hangbin Xia, Huili Li, Jing Yu, Yumei Que, Zhen Zeng, Chen Fan, Chen Wang, Chen Yang*, Jiang Chang*. Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling. Journal of Orthopaedic Translation, 2024, 48, 146-155.
21.Zhaowenbin Zhang#, Di Chang#, Zhen Zeng, Yuze Xu, Jing Yu, Chen Fan, Chen Yang*, Jiang Chang*. CuCS/Cur composite wound dressings promote neuralized skin regeneration by rebuilding the nerve cell “factory” in deep skin burns. Materials Today Bio, 2024, 26, 101075.
22.Yumei Que#, Jiaxin Shi#, Zhaowenbin Zhang#, Lu Sun, Hairu Li, Xionghai Qin, Zhen Zeng, Xiao Yang, Yanxin Chen, Chong Liu, Chang Liu, Shijie Sun, Qishu Jin, Yanxin Zhang, Xin Li, Ming Lei, Chen Yang*, Hai Tian*, Jiawei Tian*, Jiang Chang*. Ion cocktail therapy for myocardial infarction by synergistic regulation of both structural and electrical remodeling. Exploration, 2024, 4, 20230067.
23.Lefeng Su#, Chenle Dong#, Lei Liu#, Yanping Feng, Jinfeng Xu, Qinfei Ke1, Jiang Chang*, Chen Yang*, He Xu*. Low-temperature trigger nitric oxide nanogenerators for antibiofilm and wound healing. Advanced Fiber Materials, 2024, 6, 512-528.
24.Yanping Feng#, Lefeng Su#, Zhaowenbin Zhang#, Yanxin Chen, Muhammad Rizwan Younis, Dongmin Chen, Jinfeng Xu, Chenle Dong, Yumei Que, Chen Fan, Yiren Jiao, Hong Zhu, Jiang Chang*, Zhihong Dong*, Chen Yang*. pH-responsive wound dressing based on biodegradable CuP nanozymes for treating infected and diabetic wounds. ACS Applied Materials & Interfaces, 2024, 16, 95-110.
25.Yu Wang#, Yiren Jiao#, Zhen Zeng, Jiang Chang, Chen Yang*, Zhihong Dong*. Three-dimensional printed Zn2SiO4/sodium alginate composite scaffold with multiple biological functions for tendon-to-bone repair. MedComm-Biomaterials and Applications, 2023, 2, 61.
26.Jing Yu#, Yuze Xu#, Zhaowenbin Zhang#, Zhen Zeng, Dongmin Chen, Ziqin Wei, Endian Wang, Yanling Zhou, Chen Yang*, Jiang Chang*. Strontium zinc silicate bioceramic composite electrospun fiber membrane for hair follicle regeneration in burn wounds. Composites Part B-Engineering, 2023, 266, 110953.
27.Yu Qiu#, Jun Tian#, Siyi Kong, Yanping Feng, Yangyu Lu, Lefeng Su, Yanling Cai, Mengjie Li, Jiang Chang*, Chen Yang*, and Xi Wei*. SrCuSi4O10/GelMA Composite hydrogel-mediated vital pulp therapy: Integrating antibacterial property and enhanced pulp regeneration activity. Advanced Healthcare Materials, 2023, 2300546.
28.Nanjian Xu#, Dezhi Lu#, Lei Qiang#, Yihao Liu, Dalin Yin, Zhiyong Wang, Yongxiang Luo, Chen Yang, Zhenjiang Ma*, Hui Ma*, Jinwu Wang*. 3D-printed composite bioceramic scaffolds for bone and cartilage integrated regeneration. ACS Omega, 2023, 8, 37918-37926.
29.Yanxin Zhang, Xin Li, Zhaowenbin Zhang, Huili Li, Dongmin Chen, Yiren Jiao, Chen Fan, Zhen Zeng, Jiang Chang, Yuhong Xu, Baowei Peng,* Chen Yang,* and Yumei Que*. Zn2SiO4 Bioceramic Attenuates Cardiac Remodeling after Myocardial Infarction. Advanced Healthcare Materials, 2023, 2203365.
30.Yumei Que, Zhaowenbin Zhang, Yanxin Zhang, Xin Li, Likai Chen, Peier Chen, Caiwen Ou, Chen Yang*, Jiang Chang*. Silicate ions as soluble form of bioactive ceramics alleviate aortic aneurysm and dissection. Bioactive Materials, 2023, 25, 716-731.
31.Zhaowenbin Zhang#, Wenbo Li#, Di Chang, Ziqin Wei, Endian Wang, Jing Yu, Yuze Xu, Yumei Que, Yanxin Chen, Chen Fan, Bing Ma, Yanling Zhou, Zhiguang Huan, Chen Yang*, Feng Guo*, Jiang Chang*. A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch. Bioactive Materials, 2023, 24, 81-95.
32.Cancan Zhao#, Chen Yang#, Qun Lou, Jiashu Yan, Xudong Wang*, and Jiang Chang*. The memory effect of micro/nano- structures activating osteogenic differentiation of BMSCs. Journal of Materials Chemistry B, 2023, 11, 3816-3822.
33.Yanping Feng#, Mingzhen Wu#, Haidong Zhang, He Xu, Huili Li, Dongmin Chen, Hongyi Jiang, Jiang Chang, Zhihong Dong* and Chen Yang*. Mild-temperature photothermal assisted CuSi nanowires for promoting infected wound healing.Frontiers in Bioengineering and Biotechnology, 2023, 11,1158007.
34.Li Deng#, Lingwei Huang#, Hao Pan#, Qi Zhang, Yumei Que, Chen Fan, Jiang Chang*, Siyu Ni*, Chen Yang*. 3D printed strontium-zinc-phosphate bioceramic scaffolds with multiple biological functions for bone tissue regeneration. Journal of Materials Chemistry B, 2023, 11, 5469-5482.
35.Ye Yuan#, Zhaowenbin Zhang#, Fandi Mo#, Chen Yang, Yiren Jiao, Enci Wang, Yuchong Zhang, Peng Lin, Chengkai Hu, Weiguo Fu*, Jiang Chang*, Lixin Wang*. A biomaterial-based therapy for lower limb ischemia using Sr/Si bioactive hydrogel that inhibits skeletal muscle necrosis and enhances angiogenesis. Bioactive Materials, 2023, 26, 264-278.
36.Jinfeng Xu#, Muhammad Rizwan Younis#, Zhaowenbin Zhang#, Yanping Feng, Lefeng Su, Yumei Que, Yiren Jiao, Chen Fan, Jiang Chang, Siyu Ni*, Chen Yang*. Mild heat-assisted polydopamine/alginate hydrogel containing low-dose nanoselenium for facilitating infected wound healing. ACS Applied Materials & Interfaces, 2023, 15, 7841-7854.
37.Xin Li, Yanxin Zhang, Qishu Jin, Qiaoyu Song, Chen Fan, Yiren Jiao, Chen Yang, Jiang Chang, Zhihong Dong*, Yumei Que*. Silicate ions derived from calcium silicate extract decelerate Ang II-induced cardiac remodeling. Tissue Engineering and Regenerative Medicine, 2023, 10.1007/s13770-023-00523-2.
38.Ruiqi Hao, Chun Wang, Chen Yang, Jiang Chang, Xiqiao Wang, Bo Yuan, Haiting Xu, Sen Zhou, Chen Fan*, Zhiming Li*. Transdermal delivery of Protocatechuic aldehyde using hyaluronic acid/ gelatin-based microneedles for the prevention and treatment of hypertrophic scars. European Journal of Pharmaceutics and Biopharmaceutics, 2023, 184, 202-213.
39.Jupei Zhang#, Zhen Zeng#, Yanxin Chen, Li Deng, Yanxin Zhang, Yumei Que, Yiren Jiao, Jiang Chang*, Zhihong Dong*, Chen Yang*. 3D-printed GelMA/CaSiO3 composite hydrogel scaffold for vascularized adipose tissue restoration. Regenerative Biomaterials, 2023, 10, rbad049.
40.Chen Fan, Qing Xu, Ruiqi Hao, Chun Wang, Yumei Que, Yanxin Chen, Chen Yang*, Jiang Chang*. Multi-functional wound dressings based on silicate bioactive materials. Biomaterials, 2022, 287, 121652.
41.Hongshi Ma#, Chen Yang#, Zhenjiang Ma#, Xiaoyue Wei, Muhammad Rizwan Younis, Hanbo Wang, Wentao Li, Zhiyong Wang, Wenhao Wanga, Yongxiang Luo*, Peng Huang*, Jinwu Wang*. Multiscale hierarchical architecture-based bioactive scaffolds for versatile tissue engineering. Advanced Healthcare Materials, 2022, 11, 2102837.
42.Chenle Dong#, Chen Yang#, Muhammad Rizwan Younis, Jing Zhang, Gang He, Xingdi Qiu, Lian-Hua Fu, Dong-Yang Zhang, Hao Wang, Wenli Hong, Jing Lin, Xueqing Wu*, Peng Huang*. Bioactive NIR-II light-responsive shape memory composite based on cuprorivaite nanosheets for endometrial regeneration. Advanced Science, 2022, 9, 2102220.
43.Qing Xu#, Feng Jiang#, Geyong Guo#, Endian Wang, MR Younis, Zhaowenbin Zhang, Feiyang Zhang, Zhiguang Huan, Chen Fan, Chen Yang*, Hao Shen*, Jiang Chang*. Targeted hot ion therapy of infected wound by glycol chitosan and polydopamine grafted Cu-SiO2 nanoparticles. Nano Today, 2021, 41, 101330.
44.Chen Yang#, Hongshi Ma#, Zhiyong Wang#, MR Younis, Chunyang Liu, Chengtie Wu*, Yongxiang Luo*, Peng Huang*. 3D printed wesselsite nanosheets functionalized scaffold facilitates NIR-II photothermal therapy and vascularized bone regeneration. Advanced Science, 2021, 8, 2100894.
45.Dong-Yang Zhang#, Hengke Liu#, Kathy S Zhu, Ting He, Muhammad Rizwan Younis, Chen Yang, Shan Lei, Jiayingzi Wu, Jing Lin, Junle Qu, Peng Huang*. Prussian blue-based theranostics for ameliorating acute kidney injury. Journal of Nanobiotechnology, 2021, 19, 266.
46.Dong-Yang Zhang#, Hengke Liu#, MR Younis, Shan Lei, Chen Yang, Jing Lin, Junle Qu, Peng Huang*. Ultrasmall platinum nanozymes as broad-spectrum antioxidants for theranostic application in acute kidney injury.Chemical Engineering Journal, 2021, 409, 127371.
47.Chen Yang#, Rui Zheng#, MR Younis, Jundong Shao, Lianhua Fu, Dongyang Zhang, Jing Lin, Zhiming Li*, Peng Huang*. NIR-II light-responsive biodegradable shape memory composites based on cuprorivaite nanosheets for enhanced tissue reconstruction. Chemical Engineering Journal, 2021, 419, 129437.
48.Chen Yang#, Zhiwei Zheng#, MR Younis, Chenle Dong, Yahong Chen, Shan Lei, Dongyang Zhang, Jiayingzi Wu, xueqing Wu, Jing Lin, Xiansong Wang*, Huang Peng*. 3D printed enzyme-functionalized scaffold facilitates diabetic bone regeneration. Advanced Functional Materials, 2021, 31, 2101372.
49.Chen Yang, Xiaoting Gao, MR Younis, TN Blum, Shan Lei, Dongyang Zhang, Yongxiang Luo, Peng Huang*, Lin Jing*. Non-invasive monitoring of in vivo bone regeneration based on alkaline phosphatase-responsive scaffolds. Chemical Engineering Journal, 2021, 408, 127959.
50.Lian-Hua Fu#, Yilin Wan#, Chao Qi#, Jin He, Chunying Li, Chen Yang, Han Xu, Jing Lin, Peng Huang*. Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy.Advanced Materials, 2021, 33, 2006892.
51.Dong-Yang Zhang#, Hengke Liu#, Chunying Li#, Muhammad Rizwan Younis, Shan Lei, Chen Yang, Jing Lin, Zhiming Li*, Peng Huang*. Ceria nanozymes with preferential renal uptake for acute kidney injury alleviation. ACS Applied Materials & Interfaces, 2020, 12, 51, 56830–56838.
52.Chen Yang, TN Blum, Jing Lin, Junle Qu, Peng Huang*.Biomaterial scaffold-based local drug delivery systems for cancer immunotherapy. Science Bulletin, 2020, 65(17), 1489-1504.
53.Dong-Yang Zhang#, Hengke Liu#, Ting He, MR Younis, Tianhui Tu, Chen Yang, Jing Zhang, Jing Lin, Junle Qu, Peng Huang*. Biodegradable Self-Assembled Ultrasmall Nanodots as Reactive Oxygen/Nitrogen Species Scavengers for Theranostic Application in Acute Kidney Injury. Small, 2020, 16, 2001518.
54.Chen Yang, MR Younis, Jing Zhang, Junle Qu, Jing Lin, Peng Huang*. Programmable NIR-II photothermal-enhanced starvation-primed chemodynamic therapy using glucose oxidase-functionalized ancient pigment nanosheets. Small, 2020, 16, 2001518.