1.苏州大学医学院生命科学学院教授、博士生导师。

2.苏州大学学术委员会委员，农业生物技术与生态研究院长，

3.中国蚕学会常务理事，中国蚕学会生理与病理学专业委员会主任委员，江苏省蚕学会副理事长。

4、江苏省生物学示范实验中心主任

1994年被评为苏州市劳动模范，

2001年入选为浙江省“151人才”第二层次培养对象、宁波市十佳科技创新青年，

2002年入选江苏省“333高层次人才培养工程”培养对象，

2007年江苏省“333高层次人才培养工程”首批中青年科学技术带头人“

2009年获江苏省“六大高峰人才”称号。

主要从事新型核酸分子（circRNA、eccDNAs）形成和分子机制，病毒与宿主分子互作、生物工厂设计，基于基因组编辑的分子聚合育种等研究。

2005年来，主持国家自然科学基金8项、主持国家重大研发项目子课题1项，国家“973”计划子课题1项、国家“863”计划子课题1项、省部级课题21项；以通讯作者发表SCI论文125余篇，以第一发明人获国家发明专利23项，主编教材3部，著书7部，获省部级二等奖2项（排名1）、三等奖1项（排名1）；培养博士研究生18人、硕士研究生65人、农业推广硕士研究生15人、教育学硕士研究生7人。

1、苏州大学学术委员会委员

2、苏州大学农业生物技术与生态研究院长

3、中国蚕学会常务理事

4、中国蚕学会生理与病理学专业委员会主任委员

5、江苏省蚕学会副理事长

6、农业部兽药评审专家

7、江苏省基础生物学示范实验中心主任

1、circRNA的形成与作用机制

2、新型环状DNA的形成与功能机制

3、生物工厂设计

4、病毒与宿主互作（融合RNA分子的形成机制与功能）

5、基于基因编辑的分子聚合育种

1、博士研究生招生学科、专业

071010生物学-生物化学与分子生物学

2、硕士研究生招生学科、专业

071010生物学-生物化学与分子生物学

3、专业硕士学位

095133农业硕士-畜牧

研究团队教师

王崇龙（教授）、胡小龙（教授）、朱敏（副教授）、张云山（副教授）

1、研究团队教师

薛仁宇（副教授）、曹广力（副教授）、王崇龙（副教授）、胡小龙（副教授）、朱敏（讲师）、张云山（讲师）、冯永杰（实验师）

2、在读博士研究生

畜牧学-特种经济动物饲养专业：沈泽恩、童新宇、邱群婻

3、在读硕士研究生

畜牧学-特种经济动物饲养科学：庞慧琳、李浏洋

4、在读专业硕士

畜牧：郭仕程、魏淑琳、郝欣悦、杜禹、殷梅、刘卓、刘哲、黄钰清、齐燕玲

一、发表论文（*通讯作者）

(1)Zhang Y, Zhu M, Zhang X, Dai K, Liang Z, Pan J, Zhang Z, Cao M, Xue R, Cao G, Hu X, Gong C*. Micropeptide vsp21 translated by Reovirus circular RNA 000048 attenuates viral replication. Int J Biol Macromol. 2022, 209(Pt A):1179-1187

(2)Zhang X, Zhang Y, Pan J, Gong C*, Hu X*. Identification and Characterization of BmNPV m6A Sites and Their Possible Roles During Viral Infection. Front Immunol. 2022,13:869313

(3)Zhang X, Liang Z, Wang C, Shen Z, Sun S, Gong C*, Hu X*. Viral Circular RNAs and Their Possible Roles in Virus-Host Interaction. Front Immunol. 2022 ,13:939768.

(4)Liang Z, Xue R, Zhang X, Cao M, Sun S, Zhang Y, Zhu M, Zhang Z, Dai K, Pan J, Cao G, Wang C, Hu X, Gong C*. β-Arrestin 2 acts an adaptor protein that facilitates viral replication in silkworm. Int J Biol Macromol. 2022,208:1009-1018

(5)Zhu M, Pan J, Tong X, Qiu Q, Zhang X, Zhang Y, Sun S, Feng Y, Xue R, Cao G, Hu X, Gong C*. BmCPV-Derived Circular DNA vcDNA-S7 Mediated by Bombyx mori Reverse Transcriptase (RT) Regulates BmCPV Infection. Front Immunol. 2022,13:861007

(6)Zhu M, Zhang Y, Pan J, Tong X, Zhang X, Hu X, Gong C*. Grass Carp Reovirus triggers autophagy enhancing virus replication via the Akt/mTOR pathway. Fish Shellfish Immunol. 2022,128:148-156.

(7)Zhu M, Dai Y, Tong X, Zhang Y, Zhou Y, Cheng J, Jiang Y, Yang R, Wang X, Cao G, Xue R, Hu X, Gong C*. Circ-Udg Derived from Cyprinid Herpesvirus 2 Promotes Viral Replication. Microbiol Spectr. 2022,10(4):e0094322.

(8)Zhang Y, Zhang X, Dai K, Zhu M, Liang Z, Pan J, Zhang Z, Xue R, Cao G, Hu X, Gong C*. Bombyx mori Akirin hijacks a viral peptide vSP27 encoded by BmCPV circRNA and activates the ROS-NF-κB pathway against viral infection. Int J Biol Macromol. 2022,194:223-232

(9)Zhu M, Pan J, Zhang M, Tong X, Zhang Y, Zhang Z, Liang Z, Zhang X, Hu X, Xue R, Cao G, Gong C*. Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40. Dev Comp Immunol. 2022,126:104244

(10)Zhang X, Zhang Y, Pan J, Zhu M, Liang Z, Shen Z, Dai K, Yan B, Dai Y, Xue R, Cao G, Hu X, Gong C*. Proteomic analysis of the exosomes secreted from Ctenopharyngodon idellus kidney cells infected with grass carp reovirus reveals their involvement in the cellular responses to viral infection. Fish Physiol Biochem. 2021, 47(4):857-867

(11)Zhang T, Gu Y, Liu X, Yuan R, Zhou Y, Dai Y, Fang P, Feng Y, Cao G, Chen H, Xue R, Hu X, Gong C*. Incidence of Carassius auratusGibelio Gill Hemorrhagic Disease Caused by CyHV-2 Infection Can Be Reduced by Vaccination with Polyhedra Incorporating Antigens. Vaccines (Basel). 2021,9(4):397

(12)Shen Z, Kumar D, Liu X, Yan B, Fang P, Gu Y, Li M, Xie M, Yuan R, Feng Y, Hu X, Cao G, Xue R, Chen H, Liu X, Gong C*. Metatranscriptomic Analysis Reveals an Imbalance of Hepatopancreatic Flora of Chinese Mitten Crab Eriocheir sinensis with Hepatopancreatic Necrosis Disease. Biology (Basel). 2021,10(6):462

(13)Shi X, Zhang Y, Zhu T, Li N, Sun S, Zhu M, Pan J, Shen Z, Hu X, Zhang X, Gong C*. Response to Bombyx mori nucleopolyhedrovirus infection in silkworm: Gut metabolites and microbiota. Dev Comp Immunol. 2021,125:104227

(14)Zhu M, Zhang X, Pan J, Zhu H, Zhang Z, Liang Z, Cao G, Hu X, Xue R, Gong C*. Tight junction protein claudin-2 promotes cell entry of Bombyx mori cypovirus. Appl Microbiol Biotechnol. 2021,105(14-15):6019-6031

(15)Yongjie Feng,Xing Zhang,Dhiraj Kumar,Sulan Kuang,BoLiu,Xiaolong Hu,Min Zhu,ZiLiang,Guangli Cao,Renyu Xue,Chengliang Gong*.Transient propagation of BmLV and dysregulation of gene expression in nontarget cells following BmLV infection.Journal of Asia-Pacific Entomology. 2021,24(893-902)

(16)Zhu M, Liang Z, Pan J, Zhang X, Xue R, Cao G, Hu X, Gong C*. Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK1. Mol Ther Nucleic Acids. 2021,25:668-682

(17)Zhang X, Zhang Y, Shi X, Dai K, Liang Z, Zhu M, Zhang Z, Shen Z, Pan J, Wang C, Hu X, Gong C*. Characterization of the lipidomic profile of BmN cells in response to Bombyx mori cytoplasmic polyhedrosis virus infection. Dev Comp Immunol. 2021,114:103822

(19)Yu L, Pan J, Cao G, Jiang M, Zhang Y, Zhu M, Liang Z, Zhang X, Hu X, Xue R, Gong C*. AIV polyantigen epitope expressed by recombinant baculovirus induces a systemic immune response in chicken and mouse models. Virol J. 2020,17(1):121

(20)Zhangyan Wang, Yunshan Zhang, Kun Dai, Zi Liang, Min Zha, Mingtian Zhana, Jun Pa, Xiaolong Hua, Xing Zhang, Renyu Xue, Guangli Cao, Chengliang Gong*.circEgg regulates histone H3K9me3 by sponging bmo-miR-3391–5p and encoding circEgg-P122 protein in the silkworm, Bombyx mori. Insect Biochemistry and Molecular Biology. 2020, 124: 103430

(21)Yongjie Feng, Dhiraj Kumar, Xiaolong Hu, Yiling Zhang, Min Zhu, Renyu Xue,Guangli Cao, Chengliang Gong*. Comparative transcriptome analysis of wing discs from Bombyx mori and Bombyx mandarina. Journal of Asia-Pacific Entomology. 2020,23:327-335

(22)Tingting Zhang, Rui Yuan, Xing Zhang, Bo Liu, Yang Zhou, Zi Liang, Min Zhu, Mingtian Zhang, Yunshan Zhang, Kun Dai, Ziyao Zhang, Manman Cao Yuchao Gu, Jun Pan, Bingyu Yan, Hanxue Zhu, Yuqun Zhou, Yongjie Feng, Renyu Xue, Guangli Cao, Hui Chen, Xiaolong Hu,Chengliang Gong*. De novo RNA-seq assembly and differential transcriptome analysis of Carassius auratus gibelio after Cyprinid herpesvirus 2 infection. Aquaculture, 2020, 519:734923

(23)Yunshan Zhang, Xing Zhang, Zi Liang, Min Zhu, Mingtian Zhang, Tingting Zhang, Ziyao Zhang, Manman Cao, Yuchao Gu, Jun Pan, Bingyu Yan, Hanxue Zhu, Renyu Xue, Guangli Cao, Yuan Gao,, Xiaolong Hu, Chengliang Gong*. Expression pattern and regulatory network of gibel carp (Carassius gibelio) miRNAs and their putative target genes in response to CyHV-2 infection. Aquaculture. 2020, 523: 735178

(24)Yunshan Zhang, Xing Zhang, Zi Liang, Kun Dai, Min Zhua, Mingtian Zhang, Jun Pan, Renyu Xue, Guangli Cao, Jian Tang, Xuehong Song, Xiaolong Hu, Chengliang Gong*. Interleukin-17 suppresses grass carp reovirus infection in Ctenopharyngodon idellus kidney cells by activating NF-κB signaling. Aquaculture. 2020, 520: 734969

(25)Xing Zhang, Yunshan Zhang, Kun Dai, Zi Liang, Min Zhu, Jun Pan, Mingtian Zhang, Bingyu Yan, Hanxue Zhu, Ziyao Zhang, Yaping Dai, Manman Cao, Yuchao Gu, Renyu Xue，Guangli Cao, Xiaolong Hu, Chengliang Gong*. N6-Methyladenosine Level in Silkworm Midgut/Ovary Cell Line Is Associated With Bombyx mori Nucleopolyhedrovirus Infection. Frontiers in Microbiology. 2020, 10:2988

(26)Zi Liang, Yahong Lu, Mengsheng Jiang, Ying Qian, Liyuan Zhu, Sulan Kuang, Fei Chen, Yongjie Feng, Xiaolong Hu, Guangli Cao, Renyu Xue, Chengliang Gong*. Alternative isoforms of BmYki have different transcriptional co-activator activity in the silkworm, Bombyx mori. International Journal of Biochemistry and Cell Biology. 2019, 116:105599

(27)Xiaolong Hua, Yaping Dai, Xing Zhang, Kun Dai, Bo Liu, Rui Yuan, Yongjie Feng, Zi Liang, Min Zhu, Mingtian Zhang, Yunshan Zhang, Ziyao Zhang, Manman Cao, Yuchao Gu, Jun Pan, Bingyu Yan, Hanxue Zhu, Renyu Xue, Guangli Cao, Hui Chen, Yujun Wang, Chengliang Gong*. Identification and characterization of novel type of RNAs, circRNAs in crucian carp Carassius auratus gibelio.Fish and Shellfish Immunology. 2019, 94: 50–57

(28)Bo Liu, Rui Yuan, Zi Liang, Tingting Zhang, Min Zhu, Xing Zhang, Wei Geng, Ping Fang, Mengsheng Jiang, Zhangyan Wang, Yongjie Feng, Xunmeng Liu, Yang Zhou, Renyu Xue, Guangli Cao, Hui Chen, Xiaolong Hu, Chengliang Gong*. Comprehensive analysis of circRNA expression pattern and circRNA–mRNA–miRNA network in Ctenopharyngodon idellus kidney (CIK) cells after grass carp reovirus (GCRV) infection. Aquaculture. 2019 258 :734349

(29)Min Zhu, Kun Li, Yinming Xuan, Zhenli Sun, Bo Liu , Dhiraj Kumar, Ming Jiang, Yunsheng Pan, Yiming Zhang, Yeping Gong, Xiaoping Lu, Deshan Yu, Xiaolong Hu, Guangli Cao, Renyu Xue, Chengliang Gong*. Host Range and Vertical Transmission of Cyprinid herpesvirus 2.Turk. J. Fish.& Aquat. Sci. 2019,19(8): 645-652

(30)Bingyu Yan, Xunmeng Liu, Yuqun Zhou, Mingtian Zhang, Ping Fang, Mengsheng Jiang, Rui Yuan, Xiaolong Hu, Guangli Cao, Renyu Xue, Hui Chen, Chengliang Gong*. Transcriptomic analysis reveals that hepatopancreatic necrosis disease in Eriocheir sinensis (Chinese mitten crabs) may be the result of autophagy and apoptosis.Aquaculture. 2020, 515:734579

(31)Xiaolong Hu, Fei Chen, Liyuan Zhu, Lei Yu, Min Zhu, ZiLiang, Xing Zhang, Renyu Xue, Guangli Cao, Chengliang Gong*. Bombyx mori cypovirus encoded small peptide inhibits viral multiplication. Developmental& Comparative Immunology. 2019，96:51-57

(32)Dhiraj Kumara, Zhenli Suna, Guangli Caoa, Renyu Xue, Xiaolong Hua, Chengliang Gong*.Study of gut bacterial diversity of Bombyx mandarina and Bombyx mori through 16S rRNA gene sequencing. Journal of Asia-Pacific Entomology,2019,22: 522–530

(33)Li K, Yuan R, Zhang M, Zhang T, Gu Y, Zhou Y, Dai Y, Fang P, Feng Y, Hu X, Cao G, Xue R, Chen H,Gong C*.Recombinant baculovirus BacCarassius-D4ORFs has potential as a live vector vaccine against CyHV-2.Fish Shellfish Immunol. 2019,92:101-110.

(34)Zhu M, Hu X, Liang Z, Jiang M, Xue R, Gong Y, Zhang X, Cao G, Gong C*. Functional characterization of BmOVOs in silkworm, Bombyx mori. BMC Genomics. 2019,20(1):342

(35)Zhang X, Xia L, Day BA, Harris TI, Oliveira P, Knittel C, Licon AL,Gong C, Dion G, Lewis RV, Jones JA.CRISPR/Cas9 Initiated Transgenic Silkworms as a Natural Spinner of Spider Silk. Biomacromolecules. 2019,20(6):2252-2264

(36)Zhang Y, Zhu L, Cao G, Sahib Zar M, Hu X, Wei Y, Xue R, Gong C*. Cell entry of BmCPV can be promoted by tyrosine-protein kinase Src64B-like protein. Enzyme Microb Technol. 2019,121:1-7.

(37)Kumar D, Sun Z, Cao G, Xue R, Hu X, Gong C*.Bombyx mori bidensovirus infection alters the intestinal microflora of fifth instar silkworm (Bombyx mori) larvae.J Invertebr Pathol. 2019,163:48-63

(38)Liang Z, Lu Y, Qian Y, Zhu L, Kuang S, Chen F, Feng Y, Hu X, Cao G, Xue R, Gong C*. Cultured cells and wing disc size of silkworm can be controlled by the Hippo pathway, Open Biol, 2018, 8(7). pii: 180029

(39)Zhu M, Hu X, Cao G, Xue R, Gong C*. Functions and impact of tal-like genes in animals with regard to applied aspects, Appl Microbiol Biotechnol, 2018,

(40)Cao G, Gong Y, Hu X, Zhu M, Liang Z, Huang L, Yu L, Xu J, Li K, Zar MS, Xue R, Gong C*. Identification of tarsal-less peptides from the silkworm Bombyx mori, Appl Microbiol Biotechnol, 2018, 102（4）:1809-1822

(41)Chen F, Zhu L, Zhang Y, Kumar D, Cao G, Hu X, Liang Z, Kuang S, Xue R, Gong C*. Clathrin-mediated endocytosis is a candidate entry sorting mechanism for Bombyx mori cypovirus, scientific reports, 2018, 8（1）：7268

(42)Zhu L, Hu X, Kumar D, Chen F, Feng Y, Zhu M, Liang Z, Huang L, Yu L, Xu J, Xue R, Cao G, Gong C*. Both ganglioside GM2 and cholesterol in the cell membrane are essential for Bombyx mori cypovirus cell entry, DEV COMP IMMUNOL, 2018, 88：161-168

(43)Hu X, Zhu M, Liu B, Liang Z, Huang L, Xu J, Yu L, Li K, Jiang M, Xue R, Cao G, Gong C*. Circular RNA alterations in the Bombyx mori midgut following B. mori nucleopolyhedrovirus infection, MOL IMMUNOL, 2018, 101：361-470

(44)Liu B, Zhou Y, Li K, Hu X, Wang C, Cao G, Xue R, Gong C*.The complete genome of Cyprinid herpesvirus 2, a new strain isolated from Allogynogenetic crucian carp, Virus, 2018, 256：6-10

(45)Rui Guo, Guangli Cao, Renyu Xue, Dhiraj Kumar, Fei Chen, Wei Liu,Yue Jiang,Yahong Lu, Liyuan Zhu, Zi Liang, Sulan Kuang, Xiaolong Hu,Chengliang Gong*.Exogenous gene can be expressed by a recombinant Bombyx mori cypovirus. Appl Microbiol Biotechnol. 2018,102(3):1367-1379

(46)Hu X, Zhu M, Zhang X, Liu B, Liang Z, Huang L, Xu J, Yu L, Li K, Zar MS, Xue R, Cao G, Gong C* .Identification and characterization of circular RNAs in the silkworm midgut following Bombyx mori cytoplasmic polyhedrosis virus infection.RNA Biol. 2018 15(2):292-301

(47)Sun Z, KumarD, Cao G, Zhu L, Liu B, Zhu M, Liang Z, Kuang S, Chen F, Feng Y, Hu X, Xue R, Gong C*. Effects of transienthigh temperature treatment on the intestinal flora of the silkworm Bombyx mori.Sci Rep. 2017, 7(1):3349

(48)Hu X, Zhu M,Liang Z, Kumar D, Chen F, Zhu L, Kuang S, Xue R, Cao G, Gong C*. Proteomic analysis of BmN cell lipid rafts revealsroles in Bombyx mori nucleopolyhedrovirus infection. Mol Genet Genomics, 2017,292(2):465-474

(49)Zhang Y, Cao G, Zhu L, Chen F, Zar MS, Wang S, Hu X, Wei Y, Xue R, Gong C*. Integrin beta and receptor for activated proteinkinase C are involved in the cell entry of Bombyx mori cypovirus. Appl Microbiol Biotechnol. 2017, 101(9):3703-3716

(50)Song X, Hu X,Sun B, Bo Y, Wu K, Xiao L, Gong C*.A transcriptome analysis focusing on inflammation-related genes of grass carpintestines following infection with Aeromonas hydrophila. Sci Rep. 2017,7:40777

(51)He L, Hu X,Zhu M, Liang Z, Chen F, Zhu L, Kuang S, Cao G, Xue R, Gong C*. Identification and characterization of vp7 gene inBombyx mori cytoplasmic polyhedrosis virus. Gene, 2017, 627:343-350

(52)Zhonghua Pan,Xuehong Song, Xiaolong Hu, Renyu Xue, Guangli Cao, Mian Sahib Zar, DhirajKumar, Yongjie Feng,Yuhong Wei, Weiye Zhang, Wei Zhang, Chengliang Gong*. Pathological Changes and Risk Factors ofHepatopancreas Necrosis Disease of Mitten Crab, Eriocheir Sinensis. Fisheries and Aquaculture Journal. 2017, 8(3): 1000220

(53)Guo R, Cao G,Zhu Y, Kumar D, Xue R, Lu Y, Hu X, GongC*. Novel Infection System of Recombinant BmBDV DNA into BmN Cells ofSilkworm, Bombyx mori. Curr Microbiol. 2016, 73(4):587-94

(54)Liu B, GongY, Li Z, Hu X, Cao G, Xue R, Gong C*.Baculovirus-mediated GCRV vp7 and vp6 genes expression in silkworm and grasscarp. Mol Biol Rep. 2016, 43(6):509-15

(55)Zheng X, GongY, Kumar D, Chen F, Kuan S, Liang Z, Hu X, Cao G, Xue R, Gong C*. Effect of BBX-B8 overexpression on development,body weight, silk protein synthesis and egg diapauses of Bombyx mori.Transgenic Res. 2016, 25(4):507-16

(56)Hao Zhang,Zhenli Sun, Bo Liu, Yinming Xuan, Ming Jiang, Yunsheng Pan, Yiming Zhang,Yeping Gong, Xiaoping Lu, Deshan Yu, Dhiraj Kumar, Xiaolong Hu, Guangli Cao,Renyu Xue, Chengliang Gong*.Dynamic changes of microbial communities in Litopenaeus vannamei cultures andthe effects of environmental factors. Aquaculture. 2016, 455: 97–108

(57)Sun Z, Lu Y,Zhang H, Kumar D, Liu B, Gong Y, Zhu M, Zhu L, Liang Z, Kuang S, Chen F, Hu X,Cao G, Xue R, Gong C*.Effects of BmCPV Infection on Silkworm Bombyx mori Intestinal Bacteria. PLoSOne. 2016, 11(1):e0146313

(58)Guo R, CaoG, Lu Y, Xue R, Kumar D, Hu X, GongC*. Exogenous gene can be integrated into Nosema bombycis genome bymediating with a non-transposon vector. Parasitol Res. 2016, 115(8):3093-8

(59)Zhang X, GuoR, Kumar D, Ma H, Liu J, Hu X, Cao G, Xue R, Gong C*. Identification, gene expression and immune functionof the novel Bm-STAT gene in virus-infected Bombyx mori. Gene. 2016, 577: 82–88

(60)Hu X, JiangY, Gong Y, Zhu M, Zhu L, Chen F, Liang Z, Kuang S, Zar MS, Kumar D, Cao G, XueR, Gong C*. Important rolesplayed by TGF- member of Bmdpp and Bmdaw in BmNPV infection. MolecularImmunology. 2016, 73:122–129

(61)Xue R, Hu X,Zhu L, Cao G, Huang M, Xue G, Song Z, Lu J, Chen X, Gong C*. Comparative transcriptomic analysis ofsilkwormBmovo-1 and wild type silkworm ovary. Sci rep. 2015, 5:17867

(62)Hu X, ShenY, Zheng Q, Wang G, Wu X, Gong C*.Bm59 is an early gene, but is unessential for the propagation and assembly ofBombyx mori nucleopolyhedrovirus. Mol Genet Genomics. 2016, 291(1):145-54

(63)Hu X, ZhangX, Wang J, Huang M, Xue R, Cao G, GongC*. Transcriptome analysis of BmN cells following over-expression ofBmSTAT. Mol Genet Genomics. 2015, 290(6):2137-46

(64).Hu X, Zhu M,Wang S, Zhu L, Xue R, Cao G, Gong C*.Proteomics analysis of digestive juice from silkworm during Bombyx morinucleopolyhedrovirus infection. Proteomics. 2015, (15):2691-700

(65)Guo R, WangS, Xue R, Cao G, Hu X, Huang M, Zhang Y, Lu Y, Zhu L, Chen F, Liang Z, Kuang S, Gong C*. The gene expressionprofile of resistant and susceptible Bombyx mori strains revealscypovirus-associated variations in host gene transcript levels. Appl MicrobiolBiotechnol. 2015, 99(12):5175-87

(66)Liu W, LiuJ, Lu Y, Gong Y, Zhu M, Chen F, Liang Z, Zhu L, Kuang S, Hu X, Cao G, Xue R, Gong C*. Immune signalingpathways activated in response to different pathogenic micro-organisms inBombyx mori. Molecular Immunology. 2015, 65(2):391-7

(67)Zhu M, LiuB, Cao G, Hu X, Wei Y, Yi J, Zhou Y, Pan G, Wang J, Xue R, Gong C*. Identification and rapid diagnosis of the pathogenresponsible for haemorrhagic disease of the gill of Allogynogenetic cruciancarp. Journal of Virological Methods. 2015, 219:67-74

(68)Li Z, JiangY, Cao G, Li J, Xue R, Gong C*.Construction of Transgenic Silkworm Spinning Antibacterial Silk withFluorescence. Molecular Biology Reports. 2015, 42(1):19-25.

(69)Zhang P,Zhong J, Cao G, Xue R, Gong C*.BmAly Is an Important Factor in Meiotic Progression and SpermatidDifferentiation in Bombyx mori (Lepidoptera: Bombycidae). Journal of InsectScience. 2014, 14:188

(70)Zhang YL,Xue RY, Cao GL, Meng XK, Zhu YX, Pan ZH, GongCL*. Nonvirus encoded proteins could be embedded into Bombyx moricypovirus polyhedral. Mol Biol Rep. 2014:2657-2666

(71)He L, Cao G,Huang M, Xue R, Hu X, Gong C*.Expression pattern of immunoglobulin superfamily members in the silkworm. Gene.2014,548(2):189-209

(72)XuehongSong, Jie Zhao, Yunxuan Bo, Zhaojun Liu, Kang Wu, Chengliang Gong*. Aeromonas hydrophila induces intestinalinflammation in grass carp (Ctenopharyngodon idella): An experimental model.Aquaculture.2014, 434:171-178

(73)Zhen Li,Guangli Cao, Renyu Xue, ChengliangGong*. Methods for transferring gene into silkworm and expression ofhGM-CSF in silk glands of transgenic silkworm. Journal of Chemical andPharmaceutical Research.2014,6(5): 118-129

(74)Xue R, HuX1, Cao G1, Huang M, Xue G, Qian Y, Song Z, Gong C*. Bmovo-1 Regulates Ovary Size in the Silkworm,Bombyx mori. PLOS ONE.2014,9(8): e104928

(75)Song Z,Zhang M, Xue R, Cao G, Gong C*.Reducing blood glucose levels in TIDM mice with an orally administered extractof sericin from hIGF-I-transgenic silkworm cocoons. Food and ChemicalToxicology.2014,67:249-254

(76)Yin Y, CaoG, Xue R, Gong C*.Construction of transformed, cultured silkworm cells and transgenic silkwormusing the site-specific integrase system from phage ?C31. Molecular BiologyReports. 2014, 41(10):6449-6456.

(77)Zhang P,Wang J, Lu Y, Hu Y, Xue R, Cao G, GongC*. Resistance of transgenic silkworm to BmNPV could be improved bysilencing ie-1 and lef-1 genes. Gene Ther. 2014, 21(1):81-88

(78)Zhang YL,Xue RY, Cao GL, Zhu YX, Pan ZH, GongCL*. Shotgun proteomic analysis of wing discs from the domesticatedsilkworm (Bombyx mori) during metamorphosis. Amino Acids. 2013,45(5):1231-1241

(79)Xue R, LiuL, Cao G, Xu S, Li J, Zou Y, Chen H, GongC*. Oral vaccination of BacFish-vp6 against grass carp reovirus evokingantibody response in grass carp. Fish & Shellfish Immunology. 2013, 34:348-355

(80)Ying Qian,Jiabin Liu, Guangli Cao, Renyu Xue, ChengliangGong*, Cloning and Sequence Analysis of Hippo Pathway Related MajorGenes of Silkworm (Bombyx mori), Advanced Materials Research,2013 ,796 : 48-56

(81)Jiabin Liu,Ying Qian, Renyu Xue, Guangli Cao, ChengliangGong*, Prediction of genes regulated by JAK-STAT signal pathway,Advanced Materials Research,2013 ,796 : 25-35

(82)Zhang P, CaoG, Sheng J, Xue R, Gong C*.BmTGIF, a Bombyx mori Homolog of Drosophila DmTGIF, Regulates Progression ofSpermatogenesis. Plos one. 2012,7(11):e47861

(83)Xue R, ChenH, Cui L, Cao G, Zhou W, Zheng X, GongC*.Expression of hGM-CSF in silk glands of transgenic silkworms usinggene targeting vector. Transgenic Res. 2012,21(1):101-111

(84)Cao,Guangli; Meng, Xiangkun; Xue, Renyu; Zhu, Yuexiong; Zhang, Xiaorong; Pan,Zhonghua; Zheng, Xiaojian; Gong,Chengliang*. Characterization of the complete genome segments fromBmCPV-SZ, a novel isolate Bombyx mori cypovirus 1 isolate, Canadian Journal ofMicrobiology. 2012 58(7):872-883

(85)Xue R, WangY, Cao G, Pan Z, Zheng X, Zhou W, GongC*. Lowering Blood Glucose of Diabetes Mellitus Mice by OralAdministration with Transgenic hIGF-I Silkworms，Journal of Agricultural and Food Chemistry,2012,60(12):6559-6564

(86)Hao-KunZhang, Guang-Li Cao, Xiao-Rong Zhang, Xiao-Juan Wang, Ren-Yu Xue, Cheng-Liang Gong*. Effects ofBmKIT3R Gene Transfer on Pupal Development of Bombyx mori Linnaeus Using aGal4/UAS Binary Transgenic System, Journal of Agricultural and Food Chemistry,2012，60(12):3173-3179

(87)XiaolinZhang, Shitang Ma, Meisong Qin, Guoliang Zhou, Lili Zhou, Yanxi Fang, Hao Yu, Chengliang Gong*. Oralimmunisation with silkworm pupae powder containing recombinant UreB of H.pylori affords prophylactic and therapeutic effects against H. pylori infectionin mice，AfricanJournal of Microbiology Research，2012，6(16)：3761-3767

(88)Zhang X, XueR, Cao G, Hu X, Wang X, Pan Z, Xie M, Yu X, Gong C*. Effects of egt Gene Transfer on Development ofBombyx mori. Gene. 2012,491(2):272-277

(89)Hu Xiaolong,Xue Renyu, Cao Guangli, Zhang Xing, Zhang Yilin, Yu Xiaohua, Zhang Yuqing, Gong Chengliang*. Elementary researchof the formation mechanism of sex-related fluorescent cocoon of silkworm,Bombyx mori. Mol Biol Rep. 2012,39(2):1395-1409

(90)Zheng XiaoJian, Lu Ye, Zhang Pen Jie, Zhang Xiao Li, Cao Guang Li, Xue Ren Yu, Gong Cheng Liang*. Effect ofinhibiting the expression of insulin-like peptide gene BBX-B8 on developmentand reproduction of silkworm, Bombyx mori. Afr. J. Biotechnol. 2012,11(10):2548-2554

(91)XiaoliZhang, Renyu Xue, Guangli Cao, Zhonghua Pan, Xiaojian Zheng, Chengliang Gong*. Silkworms canbe used as an animal model to screen and evaluate gouty therapeutic drugs.Journal of Insect Science.12:4

(92)HaokunZhang, Guangli Cao, Yanmei Li, Renyu Xue, ChengliangGong*. Expression of human Glanulocyte Marcophage colony stimulatingfactor in stably-transformed BmN cells and Sf-21 cells and silkworm by anon-transposon vector，JOURNALOF ANIMAL AND VETERINARY ADVANCES，2012(11)16:2890-2897

(93)Renyu Xue,Qin Zhang, Yuhong Wei, Yuexiong Zhu, Xiaoyan Zhou, Guangli Cao, Chengliang Gong*. Sequentialmethod for rapid early diagnosis of white spot syndrome virus in crayfish.African Journal of Biotechnology. 2012,11(58):12232-12239

(94)Cong L, CaoG, Renyu X, Zhonghua P, Xiaojian Z, Zhou W, Gong C*. Reducing blood glucose level in diabetes mellitusmice by orally administering the silk glands of transgenic hIGF-I silkworms.Biochem Biophys Res Commun. 2011, 410(4):721-725

(95)Li Y, Cao G,Wang Y, Xue R, Zhou W, Gong C*.Expressionof the hIGF-I gene driven by the Fhx/P25 promoter in the silk glands of germlinesilkworm and transformed BmN cells. Biotechnol Lett. 2011, 33(3):489-494

(96)Wang, X.;Cao, G.; Xue, R.; Xie, M.; Zhang, X.; Yu, X.; Gong, C*. Effects of BmKIT3R gene transfer on thedevelopment and survival of silkworm Bombyx mori. J Biosci Bioeng.. 2011,112(6)：523-528

(97)Lu Ye, ZhengXiao Jian, Xue Ren Yu, Cao Guang Li, Shen Wei De, Gong Cheng Liang*. Antiproliferative activity of recombinanthuman interferon-λ2 expressed in stably transformed BmN cells. Afr. J.Biotechnol. 2011,10(37): 7260-7266

(98)Zhang X,Shen W, Lu Y, Zheng X, Xue R, Cao G, Pan Z, Gong C*. Expression of UreB and HspA of Helicobacter pyloriin silkworm pupae and identification of its immunogenicity. Mol Biol Rep. 2011,38(5):3173-3180

(99)Cao G, ZhangY, Xue R, Zhu Y, Wei Y, Zheng X, GongC*. Alternative splicing, expression patterns and promoter charactersof vasa-like gene from the silkworm, Bombyx mori. Mol Biol Rep. 2012, 39(5):5967-5976

(100)Guangli Cao,Renyu Xue, Yuexiong Zhu, Yuhong Wei, ChengliangGong*. Nuclear mitochondrial DNA pseudogenes in the genome of thesilkworm, Bombyx mori. J Comp Biol Bioi Res. 2011, 3(7): 103-119

(101)CUI Lin-Lin,XUE Ren-Yu, LUYe, CAOGuang-Li, GONGCheng-Liang*. Expression of hIL-28A in Transgenic Silkworm Mediated byNon-transposon Vector. Progress in Biochemistry and Biophysics. 2011,38(8):724-729

(102)Hu XL, CaoGL, Xue RY, Zheng XJ, Zhang X, Duan HR, GongCL*. The complete mitogenome and phylogenetic analysis of Bombyxmandarina strain Qingzhou. Mol Biol Rep. Mol Biol Rep. 2010, 37(6):2599-2608

(103)Li Y, Cao G,Chen H, Jia H, Xue R, Gong C*.Expression of the hGM-CSF in the silk glands of germline of gene-targetedsilkworm. Biochem Biophys Res Commun. 2010,391(3):1427-1431

(104)MENGXiang-kun, GONG Cheng-liang, XUE Ren-yu, CAO Guang-li, ZHU Yueyong, GONG Chengliang*. Cloning andsequence analysis of lef-3 gene from Pieris rapae granulovirus. AgriculturalSciences In China. 2010,9(5)：681-689

(105)RY Xue, X.Li, Y. Zhao, XL Pan, XX Zhu, GL Cao, CLGong*. Elementary research into the transformation BmN cells mediatedby the piggyBac transposon vector. J Biotechnol. 2009,144(4):272-278

(106)Zhao Y, LiX, Cao G, Xue R, Gong C*.Expression of hIGF-I in the silk glands of transgenic silkworms and intransformed silkworm cells. Sci China C Life Sci. 2009, 52(12):1131-1139

(107)LU Yin-Song,XUE Ren-Yu, CAO Guang-Li, ZHANG Peng -Jie, LIU Bo, GONG Cheng-Liang*. Resistance to BmNPV of TransformationCells Expressing Short lef-1 dsRNA. Progress in Biochemistry and Biophysics.2009, 36(10): 1356-1363

(108)Wenlin Zhou, Chengliang Gong, Renyu Xue,Guangli Cao, Jinru Cao, Aihong Ye, Hongbiao, Weng,Yongqiang Wang. GermlineTransformation of the Silkworm Bombyx mori L. by Sperm-MediatedGeneTransfer. BIOLOGY OF REPRODUCTION,2012, 87(6):144, 1–5

二、专利（第一发明人）

(1)人表皮生长因子核酸序列及其应用，ZL 200410065878.x

(2)一种发育可控的家蚕的构建方法及发育控制方法，ZL200810243141.0

(3)一种提高原蚕产卵量的方法，ZL201310184009.8

(4)一种载有人胰岛素样生长因子-I基因的重组转基因载体及其应用，ZL201110142537.8

(5)一种草鱼出血病口服疫苗的制备方法，ZL201210116061.5

(6)一种家蚕生物反应器制备人白介素28A的方法及其制药用途，ZL201010161096.1

(7)一种构建转基因家蚕微孢子虫的方法，ZL201210242668.8

(8)改造重组家蚕核型多角体病毒的基因工程载体的构建方法，ZL200510037703.2

(9)制备转基因家蚕的方法及其制药用途，ZL200510037759.8

(10)一种控制家蚕蛹期发育的方法，ZL201110175284.4

(11)一种家蚕质型多角体的体外构建方法,ZL201510209183.2

(12)一种表达红色荧光蛋白的重组家蚕质型多角体病毒的构建方法,ZL201510209184.7

(13)基于杆状病毒表达系统制备包裹鲤疱疹病毒II型抗原的多角体方法， ZL201710109641.4

(14)一种基于DNA载体的家蚕质型多角体病毒的体外构建方法,ZL 201810 535576.6

(15)一种基于杆状病毒载体的鲤疱疹病毒II型DNA疫苗及其构建方法与应用.ZL201810534457.9

三、著书

(1)中国养蚕学（十三五国家重点图书出版规划项目），上海科学技术出版社，2020，贡成良（没有排名）。

(2)Trends in Insect Molecular Biology and Biotechnology,Kumar, Dhiraj; Gong, Chengliang (Eds.), Springer Nature, 2017, SBN 978-3-319-61342-0。

(3)Natural Materials and Products from Insects: Chemistry and Applications，Dhiraj Kumar, Sadhana Shrivastava, Chengliang Gong,and Sangeeta Shukla. Silk: An Amazing Biomaterial for Future Medication，39-50. 2020, SBN 978-3-030-36609-4/Springer Nature

(4)家蚕病理学（全国高等农业院校教材，全国高等农业院校教学指导委员会审定）。北京：中国农业出版社， 2001，主编：金伟；副主编：鲁兴萌：编者：万永继、贡成良、廖富萍。

(5)蚕病的发生与防治,南京，江苏科技出版社,1994年,编者：钱元骏、吴友良、郭锡杰、贡成良。

(6)蚕桑高新技术研究与进展，中国农业大学出版社，2012年，主编：鲁兴萌，编委：楼程富，谈建中，贡成良，缪云根，吴小锋，朱祥瑞，曹广力，薛仁宇

(7)生物化学与分子生物实验指导，苏州，苏州大学出版社，2010年，主编：贡成良，曲春香.

(8)家蚕饲养与良种繁育学（新世纪蚕学特色专业系列教材），北京，高等教育出版社，2015，主编：朱勇，编者:刘劲、许雅香、贡成良、李春峰、吴大洋、张高军、林英、林健荣、赵天福、潘中华

(9)蚕病的识别与防治, CCTV-7,1999,剧本主编:贡成良